epi 1:1000 (adrenaline)

Question 1

What is epi 1:1000 (adrenaline)

Answer 1

stimulates sympathetic receptor (sympathomimetic)

Question 2

What is epinephrine 1:1000 mechanism of action

Answer 2

alpha1 agonist (vasoconstriction)
beta1 agonist (increases HR, contractions force, electrical conduction speed) 
Beta2 agonist (dilates bronchial smooth muscle) 
block histamine receptor

Question 3

Why give it (ADRENALINE)?

Answer 3

bronchospasm
COPD/asthma (open up bronchioles)
allergic reaction

Question 4

Why NOT give it (adrenaline)? `

Answer 4

none in emergencies

relative- hen, pulmonary edema, myocardial ischemia

Question 5

Side effects of epi ?

Answer 5

headache, restlessness,anxiety,pulmonary edema, dysrhythmia, chest pain, tachycardia

Question 6

what if we mix with other drugs?

Answer 6

potentiates (enhances) other sympathomimetic drugs

Question 7

Dose for epi 1:1000

Answer 7

0.3-0.5mg IM may repeat 15-30 min

Pedi- 0.01 mg/kg

Question 8

what pregnancy class is epi?

Answer 8

C - do not give during active labor

NOTE: it increases myocardial oxygen demand