Rabbit Medicine Flashcards
Name the symbiotic yeast found to line the stomach of rabbits
Cyniclomyce guttulatas (Saccharomycopsis guttulata)
Gastric pH juvenile (preweaned rabbits)
5.0-6.5
Gastric pH adult rabbit
1.0-2.0 (3.0 following ingestion cecotropes)
Common ear mite in rabbits
Psoroptes cuniculi
What comprises the GALT in rabbits
- Peyer’s patches (jejunum and distal ileum)
- Sacculus rotundus (ileocecal junction)
- Vermiform appendix (distal terminus of cecum)
Role of vermiform appendix
Secrete water and bicarbonate into cecum for fermentation
Four sections of LI
- ~10cm anterior (taeniae with three sacculated haustra)
- ~20cm single longitudinal taenia and haustrum
- separated by fusus coli which is unique to rabbits - ~4cm densely innervated and banded circumferentially with muscle and lacks taeniae and haustra with LOTS of goblet cells.
- Distal colon ~80-100cm from fusus coli to rectum. Short crypts and numerous goblet cells.
What connects the ileum, cecum, and proximal colon?
ampulla caecalis coli
What hormone mediates absorption of water, K+, and Na+ during digestion?
aldosterone
What do cecal goblet cells produce
Mucin
Digestible energy requirements in rabbits
400kJ/day^-1/kg^-1 x LW^0.75
Raising cecal pH in rabbits fed high protein diets causes what?
Overgrowth of Clostridia and Escherichia in cecum
What vitamins do cecotropes provide?
Vitamin K, Vitamin B
Congenital progressive and fatal disorder of sodium transport in cecum is found homozygous in what breeds?
spotted (English Spot) and Checkered GIant breeds.
Bacterial cause of enterotoxemia
Clostridium spiroforme
What age group of rabbits is most commonly affected by clostridium spiroforme?
Newly weaned (3-6 weeks)
Enterohemorrhagic E coli produces a shiga toxin that causes what clinical signs
hemorrhagic colitis with hemorrhagic diarrhea
Rabbits naturally infected with enterohemorrhagic E coli develop what hallmark sign of the shiga toxin
thrombotic microangiopathy
Subsequent litters of does infected with E coli may have passive immunity: T or F
True
What antibiotics are used to treat enteropathogenic E coli infections in rabbits?
Sulfatrim or Baytril
Obligate intracellular pathogen reported as a cause of enterocolitis in rabbits and in association with E. coli
Lawsonia intracellularis
Cause of proliferative ileitis characterized by epithelial hyperplasia nad mucosal inflammation
Lawsonia intracellularis
Disease in pigs and ferrets caused by this bacteria, which has similar signs as Lawsonia intracellularis
Desulfovibrio desulfuricans
Antibiotics used to treat Lawsonia
Macrolides (tylocin, erythromycin, lincomycin) in non-rabbits.
Chloramphenicol BID x 7-14 days in rabbits.
What bacteria causes Tyzzer’s disease
Clostridium piliforme
Clinical signs of Tyzzer’s disease
watery diarrhea, depression, death.
Causes of Tyzzer’s disease
Stress (overcrowding, unsanitary conditions, high temperatures, breeding)
Pathology findings of Tyzzer’s disease
Characteristic foci of necrosis in the liver and degenerative lesions of the myocardium. Edematous intestinal wall.
What common cleaner kills Clostridial spores
0.3% sodium hypochlorite solution (bleach), or heating to 173 degrees F for 30 minutes.
What antibiotics are Campylobactor bacteria susceptible to?
Chloramphenicol.
Resistant to fluoroquinolones and macrolides.
What virus (genus) causes rabbit hemorrhagic disease virus (RHDV)?
Lagovirus (genus)
Caliciviridae (family)
How is RHDV spread?
urine, feces, respiratory via direct contact, with carcasses, or fur from affected rabbits, or contact with fomites (water, feed, utensils, clothing, cages), and flies, and insects are vectors.
What pathologic signs are seen with RHDV?
Severe hepatic necrosis and death from DIC. Splenomegaly (dark and thickened). Congestion and hemorrhage of the lungs. Pale, reticulated pattern in liver.
Hematology or RHDV
lymphopenia and gradual thrombocyotpenia. prolonged PT and APTT times.
Clinical signs of RHDV
May also cause febrile, lethargic, anorexic, constipated, or diarrhea signs. Tachypnea, cyanosis, foamy nasal discharge.
RHDV2 major capsid protein
VP60
Clinical signs of rabbit coronavirus and diagnosis
lethargy, diarrhea, abdominal swelling, death.
Pleural effusion and cardiomyopathy. High mortality within 24 hours.
The virus causes hemagglutination in feces- needed for dx.
Common age of coronavirus outbreaks
3-10 weeks old, but also found in clinically normal adults.
Rotavirus attacks which portions of intestine
Differentiated enterocytes lining tips of villi in jejunum and ileum
Affects infant rabbits.
Human enzyme-linked immunosorbent assay test kits will detect rotavirus group A in rabbits: T of F
True
Pathology findings of rotavirus
severe billus blunting, villus fusion, and submucosal edema of small intestines, and fluid cecal contents
Eimeria stiedae infects what organ of the rabbit
Liver. The rest are in the intestines
Cause of hepatic coccidiosis
Eimeria stiedae
Most common intestinal coccidia
Eimeria perforans #1.
E. magna, E media, E irresidua.
Cecotrophs eaten from anus can spread coccidia: T or F
False
Treatment for coccidiosis
sulfadimethoxine for 7 days, amprolium in drinking water. Treatment is to limit multiplication until immunity develops.
Cause of discrete and transitory diarrhea in young rabits peaking at 30-40 day ages
Cryptosporidium parvum- no effective treatment
Nonpathogenic flaggelates and locations in rabbits
Giardia duodenalis (anterior region of small intestine)
Monocercomonas cuniculi and Retortamonas cunicula (cecum)
Entamoeba cuniculi (cecum and colon)
Large ciliated protozoa such as those of the genus Isotricha in ruminants
Common pinworm of rabbits
Passalurus ambiguus (cecum and colon). Nonpathogenic.
Via ingestion cecotrophs.
Treatment: Thiabendazole q 10-14 days
Gastrointestinal neoplasia of rabbits and location
Stomach (leiomyoscarcoma and adenocarcinoma)
Intestine (leiomyomaand leiomyosarcoma)
Sacculus rotundus and rectal squamous columnar junction (papilloma)
Bile duct (adenoma and carcinoma)
Metastatic uterine adenocarcinoma
Most common liver lobe to torse.
Caudate lobe #1
Right lobe, quadrate an dposterile lobule of left lobe also possible.
Two common aflatoxins
Aspergillus flavus and A parasiticus.
Rabbits have lowest LD50.
Pathology findings of aflatoxin ingestion
Death 3-4 days.
COngested and icteric livers, and distended gall bladder with inspissated bile.
Pneumonia is generalized in rabbit due to the lack of septa to divide the lungs into lobules: T or F
True
Rabbits are a common research model for rhinitis and sinusitis: T or F
True
What bacteria causes crusting of the mucocutaneous borders of the nose, lips, and eyelids. Crusting of nares.
T. cuniculi (rabbit syphilis) is not a primary respiratory pathogen.
Treat once weekly with procaine/benzathine penicillin for 3 weeks.
Cause of nasal granulomas in rabbits
Mycobacterium spp
Bacteria commonly isolated for rabbits with pyometra or metritis
P multocida and S aureus
Cylindrical blood clots molded with uterine horns indicate which condition
Endometrial Venous Aneurysms
Bacterial cause of late term (>21d) abortions
Listeria spp.
Abortion with fetal resorption can be induced by administering this drug once daily on days 15 and 16 after mating
aglepristone
Bacterial cause of epididymitis or orchitis
P multocida.
Cause of vesicle formation, ulcerations and scabs on vents.
T. paraluiscuniculi (rabbit syphilis or vent disease)
Treatment of T paraluiscuniculi
Parenteral (never oral) Pen G IM SID x 5-7d
Intestinal calcium absorption is independent of Vit D3 levels in rabbits: T or F
True
Sedative drug that relaxes urethral sphincter
Midazolam
What is Masugi nephritis?
Inflammatory nephritis induced by continuous immunization with large doses of antigen.
Treatment for Masugi neprhitis
Tea polyphenols
When rabbits ar eplaced on a low-calium, high-phosphorous diet, uremic rabbits (renal failure) will develop what condition?
Secondary hyperparathyroidism
What low level of Vit D may cause toxicity?
5x normal
Hypervitaminosis D causes what clinical signs
In weeks to months- mineral deposition in tissues, aorta, kidneys.
Kidneys multifocal, tan-gray throughout cortices.
What vitamin protects kidneys during aminoglycocide therapy
Vit B6
Tiletamine in Telazol causes what condition?
Nephrotoxicity- nephrosis at low doses and severe irreversible nephrosis at high doses.
Long term NSAIDs (diclofenac) causes what condition?
Significant ultrastructural renal alterations, increased renal artery vasoconstrictor activity
What breed of rabbits has a high incidence of autosomal rescessive mutations leading to renal agenesis (only 1 kidney)?
Havana breed
In males, the ipsilateral testicle is often missing
What condition causes nonsuppurative, granulomatous nephritis?
Encephalitozoonosis (nosematosis) by E. cuniculi
E cuniculi spores have a predilection for which tissues?
kidneys (31 days), brain, spinal tissue
How long are E cuniculi spores excreted in the urine
up to 3 months
How often is diethylstilbestrol given to spayed females in hormone-responsive urinary incontinence
1-2x weekly PO
What does the IRE (isolated rabbit eye) test?
irritation or corrosion to teh corneal surface by scoring swelling and corneal opaicity, and area of corneal involvement + fluoroscein penetration.
What are the cons of IRE tests
Lack of tear film causes higher false positives
Iridal damge from inflammatory or neuromusclar components cannot be assessed
What are cons of ICE (isolated chicken eye) test?
surfactants and alcohols results in false negative and false positives
When is BCOP (bovine corenal opacity and permeability) not acceptable?
When assessing mild irritancy. BCOP suitable for moderate, severe, and very severe eye irritants
Cons of ex vivo non-ocular organotypic models
Do not address conjunctival and iridial responses, inflammation and corneal recovery, or reversibility of lesions
What is the Anton test?
Used to identify Listeria monocytongenes; culture specimen is injected into rabbit conjunctiva to determine pathogenicity.
Anton discovered Listeria causes hemolysis in blood agar
Which rabbit is NOT a specific genetic model for atherosclerosis?
Saint Thomas Hospital Rabbit
Watanabe heritable hyperlipidemic rabbit
Flemish giant rabbit
Kurosawa-Kusanagi hypercholesterolemic rabbit
Flemish Giant
Why are Watanabe heritable hyperlipidemic rabbits (WHHR) used for atherosclerosis testing?
Analogous to human familial hypercholesterolemia due to genetic deficiency of LDL receptors
Vitamin A deficiency causes?
Hydrocephalus, cerebellar herniation in neonates
Keratitis progresses to iridocyclitis in adults
What is palatochisis
Cleft Palate
Palatochisis commonly occurs with what conditions?
Spina bifida
Hydrocephalus
Dwarfism
(NOT Chordoma)
What compound topically induces sensitization and when applied to rectum causes ulcerative colitis
DNCB (Dinitrochlorobenzene)
WHHL model of atherosclerosis
Decreased LDL concentration in WHHL
Hypercholesterolemia
KHC (Kusanagi Hypercholesterolemic) model of athersclerosis
Decreased HDL concentration in KHC High serum cholesterol High Triglycerides High phospholipid 12 base pair deletion of LDL on mRNA Hypercholesterolemia High coronary xanthoma
What is the homozygous (partial dominant trait) Pelger-Huet anomaly?
IFailure of nuclei of neutrophils (an eos) to mature to normal segmented form. PHA occurs secondary to mutation in the lamin B receptor and a left shift always appears to be precent.
RITARD technique is used to produce a rabbit model of what human dz?
Campylobacter enteritis, E coli, and aeromonas origin
What does RITARD stand for?
Rabbit intestinatl tie-adult rabbit diarrhea
What drug induces acute respiratory distress syndrome?
Phorbol myristate acetate (given daily IV)
Osteopetrosis (os/os) occurs in what rabbit breed?
Autosomal recessive (os) Dutch Belted
Most common cause of clostridial enterotoxemia rabbits
Clostridum spiroforme
Congenital buphthalmia pressures are normal until what age?
3 mos
Name two genera pinworms found in rabbits
Passalurus ambiguus and Passalurus nonanulatus;
Syphacia
Definitive host for taenia psiformis and taenia serialis?
Dogs
Monckeberg dz characterized by what?
medial calcific sclerosis/vessel hardening, where calcium deposits are found in the muscular middle layer of the walls of arteries
Rabbit ear mite
Psoroptes cuniculi
What separates the proximal and distal colon
Fusus coli
Normal finding with rabbit RBCs
anisocytosis
The Guide recommendation for rabbit room temperature
61-72 F
What makes the rabbit kidney unique?
The renal tubules can be separated from kidney slices with the basement membrane intact!
What enzyme do rabbits lack that is necessary for liquefying pus?
Myeloperoxidase in rabbit heterophils
Common bacterial cause of moist dermatitis
Pseudomonas aeruginosa
What type of pigment causes blue-green discoloration caused by P aeruginosa?
Pyocyanin pigment
The superficial digital flexor is kept under tension (T or F)
True
Bacterial cause of rabbit syphilis
Treponema paraluis cuniculi
Treponema paraluis cuniculi is transmitted by?
Sexual tranmission,
direct contact, or contact of young with infected dam at birth
Rabbit syphilis is zoonotic. T or F
False
List the clinical signs of rabbit syphilis.
redness, swelling, and ulceration of skin around anogenital region. Then secondary scabs and ulcers around eyes and nose from cecotrophy and grooming.
Incubation period of rabbit syphilis
10-16 weeks
Serologic testing of rabbit syphilis must occur after 8-12 weeks. T or F
True
What is the treatment of rabbit syphilis
Benzathine penicillin G/procaine penicillin G SC q7 days for 3 weeks.
What causes the skin infection necrobacillosis?
Fusobacterium necrophorum (gram negative anaerobe)
How do rabbits develop necrobacillosis?
Fecal contamination of wounds.
Common dermatophytes of pet rabbits.
Microsporum canis or M. gypseum
Common dermatophytes of laboratory rabbits.
Trichophyton mentagrophytes
Common anatomical location for dermatophytosis
Nasal planum, eyelids, and pinnae. Then legs, feet, nailbeds. Erythema and dry, yellow crusting.
What is the only dermatophyte to fluoresce under a Wood’s lamp?
M. canis
How to diagnose T. mentagrophytes?
indirect ELISA, dermatophyte culture,
What special stains are used to identify dermatophytes?
Periodic-acid Schiff, Gridley, or Gomori’s methenamine silver stain
Common ear mite in rabbits
Psoroptes cuniculi
Lifecycle of psoroptes cuniculi
21-day cycle on animal, but can live weeks off host in normal environmental temperatures
Common early sign of ear mites in rabbits
Dry grayish-white tan crusty exudate
Common fur mite in rabbits
Cheyletiella parasitorvorax (non-burrowing)
Life cycle of Cheyletiella parasitorvorax
14-21 days. Eggs survive 10 days off host.
Chyletiella is zoonotic T or F
True
Skin biopsies if conducted on rabbits with chyletiella reveal what?
hyperkeratosis with mixed inflammatory cell infiltrate
Name a non-burrowing, non-pathogenic mite
Leporacarus (Listrophorus) gibbus
Brown in color, laterally compressed with short legs
Eggs smaller, stick more distally, less firmly attached than Cheyletiella.
Highly contagious burrowing mites in rabbits
Sarcoptes scabiei var. cuniculi (head, neck, trunk, genitalia) and Notoedres cati var. cuniculi (head only)
Clinical signs of burrowing mites
Yellow, crusty dermatitis
Thin, elongated mite, obligate host-specific parasite of rabbits
Demodex cuniculi
Blood-feeding ectoparasite where only protonymphs and adults found on host.
Ornithonyssus bacoti (tropical rat mite)
Common rabbit flea
Spilopsyllus cuniculi (rabbit flea) - affects face and ears
Eastern rabbit flea
Cediopsylla simplex
Giant eastern rabbit flea
Odontopsyllus multispinosus
Stick tight flea
Echidnophaga gallinacea
Fleas rabbits most commonly affected by:
Ctenocephalides felis (cat flea) Ctenocephalides canis (dog flea) Affects dorsum and tail
Disease fleas can transmit to rabbit
Myxoma virus
Sucking rabbit louse (lice)
Haemodipsus ventricuosus - Pediculosis
Disease lice can transmit to rabbit
Tularemia
Disease black flies (Simuliidae) can spread
Myxoma virus
Obligate secondary blowfly that lays eggs in wounds or body orifices of rabbits
Wohlfahrtia vigil (grey flesh fly)
Primary fly strike attracted to soiled skin
Calliphoridae
First stage larve that enter body through nasal or oral openings
Cuterebra
Rabbit pinworm
Passalurus ambiguus (oxyuriasis) - nonpathogenic
Rabbit tapeworm
Rabbits are intermediate host- causes 4-5cm cyst (coenurus) in connective tissue
Sylvilagus spp rabbits do not develop systemic disease of myxoma visurs. T or F
True
Sylvilagus brasiliensis
Jungle rabbit
Sylvilagus bachmanni
Brush rabbit
Myxomatosis incubation
8-21 days
Causes of myxomatosis
biting arthropods or direct contact (uncommon)
Clinical signs of myxomatosis (poxvirus)
Swollen eyelids and ear margins, genital swelling, ocular discharge and peri-ocular edema, skin nodules up to 1cm, and death from septicemia in 10-14 days. Acute death can occur in 5-7. No treatment
Shope fibroma affects which species of rabbit
Sylvilagus - fibromas occur on feet, legs, and offasionally face and back and regress over time.
Shope papilloma virus is caused by?
biting insects.
Shope pappilloma virus experimentally causes what in Oryctolagus species?
malignant transformation to squamous cell carcinoma.
Oral papillomavirus undergoes carcinomatous transformation. T or F
False
What immunoreaction causes sebaceous adenitis
T-cell-mediated autoimmune rxn at sebaceous glands and hair follicles.
Sebaceous adenitis has been linked to what condition in rabbits
Thymoma and autimmune hepatitis
Clinical signs of sebaceous adenitis
nonpruritic, chronic exfoliative dermatitis. Hair epilaes easily with keratin debris around hair shaft (follicular casts)
What is used to treat sebaceous adenitis?
cyclosporine and miglyol
What condition causes joint laxity, skin hyperextensibility, and skin fragility
Ehlers-Danlos-like syndrome (cutaneous asthenia)
Most common disease affecting the external pinna
ear mites (P. cuniculi)
Microsporidium, obligate intraceullar pathogen
Encephalitozoan cuniculi
Clinical signs of E cuniculi
head tilt, nystagmus, ataxia, circling, rolling (vestibular disease)
Components of E cuniculi spore
Polar filament, nucleus, electron-dense sporoplasm
Spore wall, endospore, and plasma membrane
Rabbits suffering from otitis interna may have signs of upper respiratory disease. T or F
True
What neurologic condition may cause unilateral facial spasm or hemifacial dysfunction
Upper respiratory infection (not E. cuniculi)
Portion of the brain most affected by E cuniculi
Cerebrum, followed by leptomeninges
What stain is more sensitive at detecting E cuniculi spores than acid fast trichrome stain?
Ziehl-Neelsen stain
Serologic testing is a means for monitoring E cuniculi infection in rabbits. T or F
True
What immunoglobulin is used for determining early disease of E cuniculi (prior to day 35)?
IgM
Treatment for E cuniculi in rabbits
Fenbendazole 20 mg/kg PO SID for 28 days.
Side effect of Benzimidazoles?
Bone marrow aplasia and intestinal tract crypt epithelial necrosis.
What parasite causes malacic tracks in affected CNS tissue
Baylisascaris species
What condition causes granulomatous meningoencephalitis, but also tachyzoits in multiple organs?
Toxoplasmosis
Treatment of toxoplasmosis in rabbits should be clindamycin (like cats). T or F
False
Treatment of toxoplasmosis in rabbits
Pyrimethamine, Bactrim, or doxycycline
What toxicosis causes CNS edema, blindness, and anemia
Lead
What is used to treat lead toxicosis
Calcium disodium ethyleneiamine tetraacetate (chelation)
What vitamin deficiency causes muscular dystropphy and degeneration of skeletal muscle myofibers causes paresis.
Hypovitaminosis E
Old feed will become deficient in what vitamin
Vitamin E
What vitamin deficiency causes hydrocephalus with stenosis of cerebral aqueduct leading to increased CNS pressure
Hypovitaminosis A
Excess of this vitamin causes resorption of bones and calcification of soft tissues, such as the aorta
Vitamin D
What vitamin deficiency causes ataxia, paralysis, and death
Hypovitaminosis D
What vitamin deficiency causes enlarged joints, crooked legs, arched backs, and enlarged rib costochondral junctions
Hypocalcemia or Hypovitaminosis D.
What vitamin deficiency causes poor bone consistency leading to brittle bones and limb problems
Manganese
What vitamin deficiency causes seizures
Magnesium
What vitamin deficiency causes muscle weakness and paralysis
Potassium
What is the most common cause of CNS neoplasia in rabbits
Lymphoma
How many valves are in the rabbit triscupid valve
2
The aortic nerve is associated with chemoreceptors. T or F
False. (Baroreceptors)
The pulmonary artery is poorly muscular. T or F
False - heavily muscular
The rabbit has a persistent left cranial vena cava that drains into the coronary sinus. T or F
True
What settings should be used for rabbit ECGs
vertical calibration: 2cm/mV
horizontal paper speed of 40 mm/s.
Rabbits have a normal respiratory sinus arrhythmia. T or F
False
What is the systolic blood pressure of rabbits
120-180 mmHg
What is the most common type of lymphoma
B-cell
Thymic lymphoma is what origin
T-cell
What is the most common cutaneous neoplasm in rabbits
Trichoblastomas basal cell tumors)
Recommended room temperature for rabbits
61-72 F (16-22 C)
Rabbits <2kg require what housing dimensions
1.5 ft2 x 16”
Rabbits up to 4kg require what housing dimensions
3.0 ft2 x 16”
Rabbits >5.4kg require what housing dimensions
> 5 ft2 x 16”
Rabbits up to 5.4kg require what housing dimensions
4 ft2 x 16”
What does it mean to have a merangiotic fundus?
Vessels run horizontally.
Common bacterial cause of conjunctivitis, epiphora, nasolacrimal duct obstruction, and dacryocystitis
P multocida
Spontaneous development of corneal dystrophy (accumulation of cholesterol or lipid crystals in cornea) occurs in which breed?
American Dutch belted rabbits
Name the breed of rabbits with heritable hypercholesterolemia which causes yellow-white granules to develop along corneal-scleral junction and the iris.
Watanabe rabbits
What condition causes phacooclastic uveitis (and cataract), often seen in young or dwarf rabbits?
E cuniculi (granulomatrous encephalitis and renal lesions too)
What bacteria can cause abscess of the iris?
P multocida
Keratitis of the cornea can be caused by which condition?
Shope fibroma virus
What is the mode of inheritance for congenital glaucoma?
Autosomal recessive
Treatment of buphthalmos?
Dorzolomide or Timolol maleate
Laser cycloablation can be used in albino rabbits. T or F
False, only pigmented rabbits
What is the name of the deep gland to the third eyelid?
Harderian gland (two lobes- dorsal white and ventral pink)
The laboratory rabbit belongs to what family?
Leporidae
What is the muscular architecture of the rabbit esophagus?
3 layers, all striated
The capacity of the rabbit cecum is what percent of the total digestive tract capacity?
40%
Volume of bile a rabbit produces per day
~250ml (~100-150 ml/kg)
Describe the right AV valve in the normal rabbit heart.
Two cusps, one large, one small
Rabbit skeleton is what percent of body weight?
8%
Neonatal rabbit is ectothermic until what age?
7 days
Architecture of reproductive tract of rabbits?
2 cervix, 2 uterine horns
Which of the following condition is not associated with a cleft palate? Spina bifida, Chordoma, Hydrocephalus, Dwarfism
Chordoma
What compound is applied topically to induce sensitization and subsequently applied of rectum of rabbit model for ulcerative colitis?
Dinitrochlorobenzene (DNCB)
The Pelger-Huet anomaly affects what blood component of rabbits?
Heterophils
The development of B-cell leukemias in rabbits with the E mu-myc transgene contrasts with the development of B-cell lymphomas in mice carrying a similar transgene. T or F
True
The RITARD technique is used to produce a rabbit model of what human disease?
Campylobacter enteritis
Daily intravenous injection of phorbol myristate acetate induced what model?
Acute respiratory distress syndrome
Osteopetrosis (os/os) occurs in rabbits of what strain?
Dutch belted
What test is not an alternative to the Draize test of ocular toxicity? Sperm motility Limus amebocyte lysate assay Water flea assay Tetrahymena thermophila assay Chorioallantoic membrane assay
Limus amebocyte lysate assay
Name the rabbit ear mite
Psoroptes cuniculi
What is considered normal for rabbit red blood cells?
Anisocytosis
Guide recommendation for rabbit room temps
61-72