Quizzes - all Flashcards

1
Q

Which specimen handling technique below is best for preserving the integrity of plasma glucose values?
a) Collect specimen in NaF
b) Refrigerate whole blood specimens
c) Remove plasma from RBCs within 2 hours of collection
d) Collect specimen in gel barrier tube and spin 30 minutes after collection

A

d) collect specimen in gel barrier tube and spin 30 mins after collection

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2
Q

Which of the following best describes handling CSF for glucose analysis?
a) Collect in tube containing NaF and place in ice after collection
b) Collect in plain tube and place on ice after collection
c) Collect in tube containing NaF, spin and test supernatant ASAP
d) Collect in plain tube, spin, and test supernatant ASAP

A

d)

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3
Q

Identify the correct statement(s) below.
a) A person with iron deficiency anemia and a hemoglobin A1c of 6.3% can be reliably diagnosed with DM
b) Hexokinase is generally considered the most reliable way to measure glucose in a clinical lab.
c) A glycated hgb of 8% suggests that a hgb variant is present
d) All of the above

A

b)

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4
Q

Choose the correct statement(s) related to the measurement of glycohemoglobin.
a) The heme portion of all hemoglobin binds glucose irreversibly where it will remain bound over the course of the red cell’s lifespan
b) As long as only hgb a1c is being measured, there is rarely interference from variant (non-A) hgb in the measurement.
c) Glycohemoglobin provides a valuable method for estimating average whole blood glucose level for the past 7 days
d) Hemolytic anemias can falsely decrease hemoglobin A1c
e) all of the above

A

d)

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5
Q

IN patients with a hematologic disorder, long term assessment of glycemic control may be best accomplished measuring:
a) total glycated hgb
b) hgb a1c
c) glycated albumin
d) fructose

A

c)

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6
Q

Of those below, which method for detecting glucose is most unreliable?
a) copper reduction
b) hexokinase
c) glucose oxidase
d) although the false positives and false negatives are due to different causes, the methods are about equal

A

a)

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7
Q

An increase in ketone bodies is most associated with
a) liver associated hypoglycemia
b) consumption of glucose in excess of the body’s needs
c) insufficient glucose in cells to meet metabolic needs
d) glucagon deficiency

A

c)

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8
Q

Which of the following is a storage mechanism of glucose?
a) Adipose tissue stores glucose as glycogen
b) liver stores glucose as glycogen
c) adipose tissue stores glucose as ketone bodies
d) Liver stores glucose as ketone bodies

A

b)

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9
Q

A patient has a blood glucose of 200 mg/dL. which result(s) below would correlate this value?
a) CSF glucose 130 mg/dL
b) Glucose detectable in urine
c) Hgb a1c >6%
d) all of the above

A

d)

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10
Q

All of the following are reducing sugars except:
a) Fructose
b) Sucrose
c) Maltose
d) Galactose

A

b)

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11
Q

In times of crisis, which of the following would you expect to occur to help you survive this threat?
a) Insulin released
b) Glycogenesis would occur
c) Epinephrine and glucagon would be released
d) Lipogenesis would occur

A

c)

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12
Q

Which of the following is TRUE regarding DKA?
a) Life threatening
b) Elevated beta-OH butyrate
c) Low blood pH
d) Dehydration
e) All of the above

A

e)

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13
Q

Patients with which conditions below are most likely to have hypoglycemia?
a) Neonate born to diabetic mother
b) Alcoholic with cirrhosis of the liver
c) Patient with intestinal malabsorption syndrome
d) All of the above

A

d)

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14
Q

Which of the following can lead to hypoglycemia?
a) insulinoma
b) cushings disease
c) pheochromocytoma
d) all of the above

A

a)

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15
Q

What is the cause of lactose intolerance?
a) Defect in the intestinal mucosa that inhibits the transfer of lactose into the body
b) defect in the liver that inhibits the transfer of lactose into the body
c) deficiency of the enzyme lactase
d) deficiency of the enzyme galactokinase

A

c)

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16
Q

Each test result below is paired correctly with a disease which would cause it EXCEPT
a) reducing substance in urine/ galactosemia
b) microalbuminnuria/prolonged poor diabetic control
c) falsely increased total glycated hemoglobin/non A1 hgb present
d) Low C peptide/insulinoma

A

d)

17
Q

Hypoglycemia associated low serum C-peptide and high serum insulin is most likely caused by

A

Overinjection of artificial insulin

18
Q

Which of the following do you usually associated with Type 2 diabetes?
a) requires insulin for survival
b) A complication includes DKA
c) if blood pH decreases, it is usually due to ketoacid production
d) has a slow onset, occurring frequently in older or obese individuals

A

d)

19
Q

Which measurement below is most reproducible within the same individual?
a) plasma glucose
b) 2 hour post prandial
c) hgb a1c
d) ketone bodies
e) OGTT

A

c)

20
Q

Which form of diabetes is associated with pancreatic autoantibodies

A

Type 1

21
Q

Each of the following is a medical decision level for plasma glucose except
a) 50
b) 126
c) 140
d) 200

A

c)

22
Q

What enzyme is used in glucose strips?

A

Glucose oxidase

23
Q

According to CLIA, what is the acceptable allowable error for a glucose specimen with a value of 300mg/dL?

A

270-330 mg/dL
(±6mg/dL or ±10%)

24
Q

If measurements on your glucometer are not linear, you will be able to tell because
a) the line will not visually look straight
b) values of controls calculated from regression line, their difference from the stated value will exceed allowable error
c) The slope of the line may be far less than 1.0
d) All of the above

A

d)

25
Q

If the SD is too high, there is a problem with too much
a) constant error
b) proportional error
c) random error
d) systemic error

A

c) random

26
Q

In your glucometer procedure, glucose concentration is proportional to
a) oxygen consumption
b) electron flow
c) color change
d) UV absorption

A

b)

27
Q

Which technique below is correct?
a) count the number of specimens you need to test and remove that number of strips from the cannister
b) remove strips immediately before needing it and tightly closing the vial immediately
c) squire sample directly from the control vial to the glucose strip which the picture doing so is shown
d) enter the exact date that you perform the test when you set up the meter

A

b)

28
Q

glucose levels in WB will decrease __ % per hour

A

5-7%

29
Q

What effect can very high hct have on WB glucose levels

A

false decrease

30
Q

What is the purpose of glucometer verification
a) establish how well the glucometer can perform
b) identify interfering substances
c) identify the cause of out of range controls
d) verify the performance is consistent with the performance observed when he method was validated.

A

d)