Quiz3 Flashcards
what are GABA and glutamate
- amino acids/ neurotransmitters that act all over the brain and nervous system
- likely the first developed or the first that evolved
what is the difference between GABA and glutamate
GABA is inhibitory
glutamate is excitatory (linked to epilepsy)
what is the cholinergic pathway
- main neurotransmitter is acetylcholine (its disfunction implicated in Alzheimers, attention and circadian rhythm)
- located in the basal forebrain projecting into the pons
what is the dopaminergic pathway
three different subsystems
1) nigrostriatial: movement/motor control
2) mesolimbic: reward
3) mesocortical: working memory/ planning
main neurotransmitter is dopamine
what is the noradrenergic pathway
- main neurotransmitter is noradrenaline
- deals with arousal, sympathetic nervous system
- located in locus coeruleus and hypothalamus
what is the serotonergic pathway
- main neurotransmitter is serotonin
- basic needs: mood, appetite, sexual behavior
- located in raphe nuclei
what can cognitive neuroscience methods accomplish
- learning brain structure
- learning where brain functioning is
- learning when processes occur
- learning how brain regions are connected/work together
- learn consequences of brain damage and how brain adapts
what are the categories of cognitive neuroscience methods
- anatomical imaging
- recording blood flow
- recording electrical activity
- observing behavior following lesion/disruption
- computational modeling of processes
what is anatomical imaging
assess brain structure/anatomy; is used in diagnosing disease and understanding individual and group anatomy
what is CAT
- computerized axial tomography
- x-rays that provide images of tissue based on density of tissue
- can determine age of legion (recent=bright, older=dark)
- can be used on all patients and is inexpensive compared to everything else
what is MRI
- magnetic resonance imaging
- uses magnetic fields to distort behaviors of protons
- gives detailed picture of brain
- great for distinguishing gray and white matter
why is MRI better than CAT
- does not use ionizing radiation
- better spatial resolution (ex. folds of gyri)
- better discrimination between white and grey matter
- adapted for use in fMRI