Quiz Review Flashcards

1
Q

ecn of alp:

A

3.1.3.1

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2
Q

-activators of alp:

A

mg&zn

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3
Q

-fastest factor isoenzyme

A

Liver

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4
Q

-most heat stable:

A

placental alp

Or REGAN??

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5
Q

-neoplastic isoenzyme for
lung, breast, ovarian, colon
cancers:

A

regan isoenzyme

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6
Q

Bone Disorders:

Highest elevations in

A

Paget’s disease (Osteitis deformans)

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7
Q

-optimal pH sa ACP:

A

5.0

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8
Q

-best method to detect isoenzymes:

most useful technique for isoenzyme analysis

A

electrophoresis

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9
Q

-: Richest source, highest activity ACP:

A

Prostate

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10
Q

-nkalimot ko sa question basta ang answer kay:

Historically used for detecting metastatic carcinoma of the prostate Less sensitive than newer markers like Prostate-Specific Antigen (PSA)

A

Prostatic Carcinoma Detection

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11
Q

Chemical inhibition

Uses substrates like thymolphthalein monophosphate

Differentiates_______ using tartrate inhibition Equation: Total ACP - ACP after tartrate inhibition =_____

A

prostatic ACP

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12
Q

Chemical Inhibition:

Uses substrates like______

Differentiates prostatic ACP using_____

A

thymolphthalein monophosphate

tartrate inhibition

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13
Q

Formula

= Prostatic ACP

A

Total ACP - ACP after tartrate inhibition

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14
Q

Not entirely specific, as lysosomal ACP is also inhibited by tartrate

A

Tartrate inhibition

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15
Q

Roy and Hillman (Quantitative Endpoint)

Substrate:

A

Thymolphthalein monophosphate

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16
Q

Babson, Read & Phillips (Continuous Monitoring)

Substrate:

A

Alpha-naphthyl phosphate

17
Q

-ref range, men 30degrees celcius:

A

5.0 u/l

18
Q

ACP

MEN

A

3.6
5.0
6.5

19
Q

WOMEN ACP

A

3.0
4.2
5.5