Finals Quiz 2 Flashcards
(De Quervain’s thyroiditis)
Hyper
• Subacute granulomatous / Subacute nonsuppurative thyroiditis
Hyper
• Graves’ disease (diffuse toxic goiter)
Hyper
• Thyrotoxicosis
Hyper
• goiter.
• Fine tremor of outstretched hands.
• Brisk reflexes.
Hyper
• Tachycardia, wide pulse pressure.
• Warm, moist skin.
• Eyeila, maybe present.
Hyper
• Weight loss despite increased appetite.
• Hyperdefecation (not diarrhea).
Hyper
• Anxiety, “hyperkinesis.”
• Sleep disturbances.
Hyper
• Heat intolerance, excessive sweating.
Hyper
- most common cause of thyrotoxicosis
- autoimmune disease
Graves’ disease (toxic diffuse goiter)
- 6x more common in women than in men
Graves’ disease
T3 thyrotoxicosis
Plummer’s disease
Subacute granulomatous / Subacute nonsuppurative thyroiditis
De Quervain’s thyroiditis
- neck pain, low-grade fever, thyroid fxn swings
De Quervain’s thyroiditis
- TPO Ab absent; ESR and Tg levels are high
De Quervain’s thyroiditis
What is primary hypothyroidism
primary- deficiency of elemental iodine; high TSH
What is secondary hypothyroidism
secondary- pituitary destruction of pituitary ademoma; low TSH
What is tertiary hypothyroidism
tertiary- hypothalamic disease; low TSH
Hashimoto’s disease
Hypo
Myxedema
Hypo
Cretinism
Hypo
Retarded skeletal growth.
Hypo
muscle weakness
Hypo
bradycardia
Hypo
constipation
Hypo
dry skin
Hypo
cold sensitivity
Hypo
hoarseness
Hypo
• tend to have low TSH results during their acute illness
Nonthyroidal Illness (NTI)
- is associated with low T4 and T3
syndrome (euthyroid sick syndrome)
NIT
• TSH rises to within or above the reference range with resolution of the underlying illness, ultimately returning to normal once the acute illness has resolved
Nonthyroidal Illness (NTI)
Thyroid Autoanitibodies
- TPOAb ( Thyroid peroxidase antibodies )
- anti-Tg Ab ( anti-thyroglobulin antibodies )
- TSH receptor Ab (TRAbs) ( thyroid stimulating hormone receptor antibodies)
Urinary lodine
- = normal
- = mild deficiency
- = moderate deficiency
- = severe deficiency
> 100 mg/L
50-99 g/L
20-49 pg/L
<20 mg/L