Quiz Flashcards
Affects children
ALL
Affects ages 40-60
AML and CML
Affects the Elderly
CLL and CML
Down syndrome increases the risk
AML and ALL
Is defined by less than 20% blast cells
Myelodysplastic syndrome
Defined by greater than 20% blast cells
Acute Leukemias
AML and ALL
Tear drop cells
Myelofibrosis
Associated with Renal Cell Carcinoma
Polycythaemia Vera
Presents with Basophilia
CML
Has increased risk of clotting
Essential Thrombocytopenia
polycythaemia Vera
Characterized as positive for TdT, CD10, CD19, and CD20
B-ALL
t(12:21) indicates a good prognosis
B-ALL
t(9:22) indicates a poor prognosis
B-ALL
Stains positive for TRAP
Hairy Cell Leukemia
Associated with HTLV-1 (Japan/Carribean)
Adult T cell Leukemia/Lymphoma
100% have the BCL:ABL (9:22 translocation)
CML
Stain positive for MPO
AML
Present with a mediastinal mass
T-ALL
t(15:17)
Acute Promyelocytic Leukemia
treated with ATRA and Arsenic
Acute Promyelocytic Leukemia
ringed sideroblasts
Myelodysplastic syndrome
Caused by JAK2 mutations
Polycythaemia Vera
Essential Thrombocytopenia
Myelofibrosis
Auer Rods
AML
Cyclin D1 mutation
Hairy Cell Leukemia
Mantle Cell Leukemia
Smudge Cells
CLL
Peptic ulcer Disease is a risk factor
Non-Hodgkin’s Lymphoma
-Marginal Zone Lymphoma
Epstein-Barr Virus
Non-Hodgkin’s Lymphomas
- Burkitt
- Diffuse Large B cell
C-myc mutation
Burkitt’s Lymphoma
Starry Sky Histology
Burkitt’’s Lymphoma
Reed-Sternberg Cells
Hodgkin’s Lymphoma
Lacunar Cells
Hodgkin’s Lymphoma
-Nodular Sclerosis subtype
CD15+ and CD30+
Hodgkin’s Lymphoma