Quiz 8

Question 1

___ regulates the growth and maturation of megakaryotes

Answer 1

thrombopoietin

Question 2

In normal adults, red blood cells are formed in

Answer 2

red bone marrow

Question 3

a hemoglobin molecule is composed of

Answer 3

four protein chains and four heme groups

Question 4

heme production relies on the presence of ___ and the enzyme ___

Answer 4

iron, ALA synthase

Question 5

under normal circumstances, aged and damaged erythrocytes are broken down by the…

Answer 5

spleen

Question 6

If you have this blood type you can accept blood from just about anyone

Answer 6

AB+

Question 7

A dead human body has been discovered in the woods near your home. You are a hematologists and the body is still warm. The adult corpse has no gender cues. How can you determine the gender?

Answer 7

Females have a lower RBC count, higher hematocrit in males

Question 8

what type of hemoglobin exists now sickle cell blood and what causes it?

Answer 8

Sickle cell anemia is a blood disease that affects red blood cells. Normal red blood cells are round. In people with sickle cell anemia, hemoglobin – a substance in red blood cells – becomes defective and causes the red blood cells to change shape. The faulty hemoglobin is called hemoglobin S, (HgbS) and it replaces normal hemoglobin called: hemoglobin A (HgbA). Over time, the red blood cells become rigid and shaped like crescent moons or sickles.

Question 9

Destruction of RBC’s can lead to bilirubin toxicity and jaundice. Based on this knowledge, why are newborns in particular susceptible to jaundice?

Answer 9

This is because when new born alpha gamma hemoglobin changes to alpha beta they produce excess bilirubin, if the liver does not get rid of it they will become jaundice

Question 10

the average life span of a red blood cell is

Answer 10

4 months

Question 11

Describe 2 major categories of pharmacological agents that can be used to treat hypertension

Answer 11

Angiotensin II Receptor Blockers and Calcium Channel Blockers