Quiz 7 - Neural Tissue/Brain & Cranial Nerves Flashcards
Wave of depolarization that is propagated across and entire cell membrane
Action Potential
The properties of the nation potential are independent of the relative strength of the depolarizing stimulus as long as that stimulus exceeds the threshold potential.
All-or-None Principle
Generation of action potential
- Depolarize membrane to threshold potential
- Activate sodium channels/Sodium ions enter cell and membrane is depolarized
- Sodium channels close/potassium channels reopen. Membrane polarizes again
- Resting potential is re-established and normal ion permeability is restored.
Junction between a neuron and another cell
Synapse
Transmission of neural impulse from one cell to another.
Synaptic Transmission
Signal jumping between myelin.
Saltation
Signals travel faster with myelin.
Space between the two cells
Synaptic cleft
Synaptic Transmission: _______ _______ of the synaptic terminal releases neurotransmitter into the synaptic cleft.
Presynaptic Membrane
Synaptic Transmission: ____________ diffuses across the synaptic cleft and reacts with the _________ membrane
Neurotransmitter
Postsynaptic
Postsynaptic membrane may be ________, GENERATING propagation of an action potential in the postsynaptic membrane.
Depolarized
Postsynaptic membrane may become __________, INHIBITING propagation of an action potential in the postsynaptic membrane.
Hyperpolarized
The effect of a neurotransmitter on the postsynaptic membrane depends on the properties of the _______, not on the nature of the _________.
Receptor
Neurotransmitter
End formation by which the axon of a motor neuron establishes synaptic contact with a skeletal muscle fiber
Motor End Plate
The ________ is modified around the motor end plate.
Sarcolemma
A single motor neuron, plus those muscle fibers controlled by it.
The motor unit
Autoimmune disease causing muscle weakness.
Myasthenia Gravis
Antibodies bind to the receptors and both the neurotransmitters.
More common and earlier onset in _________ (men/women).
Myasthenia Gravis
Women
Symptom: Trouble blinkning, swallowing, tracking with eyes.
Myasthenia Gravis
Neurotoxin prevents muscle contraction by preventing release of neurotransmitter from motor neuron.
Botulism
Mis-canned food is a prime source for ______.
Botulism
Neurotoxin causes excessive stimulation of target muscle, which results in severe muscle spasms and sustained muscle contractions.
Tetanus
Open wounds are susceptible to ______.
Tetanus
Potential at which sodium-channels open, allowing sodium ions to readily enter the cell; depolarization to -60 to -55mV (small kids opening fire door… once that threshold is reached, it doesn’t matter if it is barely reached or 10x what’s necessary)
Threshold Potential
Local changes in membrane potential can be additive if they occur close together in time or space (multiple signals close together in time or space)
Summation
Amount of change is directly proportional to the size of the stimulus.
Graded Potential
Resting potential becomes more negative vs. resting potential becomes less negative
Hyperpolarizing vs. Depolarizing
Myelinate axons of the PNS
Schwann Cells
A cluster of neuron cell bodies
Ganglion
Surround and provide support for neuron cell bodies within a ganglion
Satellite Cells
The multi-layered membranous wrapping formed by the oligodendrocyte; increases the speed of action potential propagation along the axon.
Myelin
Process wrap around axons of the CNS, INSULATING them
Oligodendrocyte
The “immune system” cells of the CNS
Microglia
Support cell for neurons in the CNS; a component of the “blood-brain barrier” (gate-keepers for what comes out of blood vessels)
Astrocyte
Epithelial cells, lining the ventricles of the brain and the central canal of the spinal cord; some specialized ependymal cells secrete cerebrospinal fluid.
Ependymal Cell
Support cells of the nervous system
Neuroglia
Cells of the afferent division of the PNS (internal & external senses)
Sensory neurons
Cells of the efferent division of the PNS
Motor Neurons
May act as connectors between sensory and motor neurons; located entirely within the CNS
Interneurons
Small, with a short axon not easily distinguished from the dendrites; primarily found in the brain and in special sense organs
Anaxonic
Has one long axon and many dendrites; most common type of neuron in the CNS
Multipolar
Appears to have one process which bifurcates into an axon and a single dendrite; most sensory neurons are _________.
Unipolar
Has one long axon and only one dendrite, positioned at opposite ends of the soma; occurs in special sense organs
Bipolar
Junction between a neuron and another cell
Synapse