Quiz 4: Pancreas Flashcards
What is a possible complication of pancreatitis?
Abscess formation
Single most common etiology of chronic pancreatitis
alcohol
What are the elevated serum enzymes in pancreatitis?
amylase and lipase
related to chelation of calcium salts with fatty acids liberated by the pancreatic enzymes
saponification
peri-pancreatic fluid collection containing high concentrations of pancreatic enzymes within a defined fibrous wall and lacking an epithelial lining
pancreatic pseudocyst
Usually unilocular, intra- or peri-pancreatic cyst containing heterogeneous material including old blood.
Pancreaticc pseudocyst
no epithelial lining and contains cholesterol clefts, blood both fresh and clotted and hemosiderin laden macs
pancreatic pseudocyst
collection of pus resulting from tissue necrosis, liquefaction, and infection, usu develop in pts with pancreatic pseduocysts that become infected
pancreatic absess
Most likely pathogen in pancreatic abscess
E. coli, klebsiella pneumoniae, enterococcus faecalis, staph aureus, pseudomonas, proteus mirabilis, strep
bacterial contamination of necrotic pancreatic tissue in the absence of abscess formation
infected necrosis
most typical organisms isolated from infected necrosis and abscesses are
enteric bacteria and candida species
3 benign tumors of the pancreas
pseudopapillary tumor, serous cystadenoma, mucinous cystadenoma
2 malignant tumors of the exocrine pancreas
pancreatic adenocarcinoma and mucinous cystadenocarcinoma
cystic epithelial neoplasms that occur almost exclusively in women
mucinous cystic neoplasm
Most frequent cystic tumors of the pancreas
mucinous cystadenomas
typically round, well-demarcated, avg 8cm, with solid and cystic areas, often with hemorrhage noted on cut sections
solid pseudopapillary tumors
sheets of cells which usu have uniform nuclei and eosinophilic or clear cytoplasm with PAS pos eosinophilic cytoplasmic inclusions
solid pseduopapillary tumors
Second most common cystic tumor of the pancreas
serous cystadenoma
tumors with a honeycombed appearance
serous cystadenoma
Associated with Von Hippel-Lindau syndrome
serous cystadenoma
small cysts which are lined by ciliated cuboidal epithelium
serous cystadenoma
most common type of pancreatic cancer
pancreatic ductal adenocarcinoma
second most common pancreatic cancer
mucinous