GI Flashcards
characterized by increased tone and pressure at the lower esophageal sphincter (LES), diminished to absent peristalsis in the distal portion of the esophagus and lack of a coordinated LES relaxation in response to swallowing.
Achalasia
4 esophageal motility disorders
Achalasia, diffuse esophageal spasm, nutcracker esophagus and hypertensive lower esophageal spasm
lymphocytic infiltration of Auerbach’s plexus and destruction of ganglion cells is likely the underlying pathophysiology that results in this condition.
Achalasia
contractions are uncoordinated and several segments of the esophagus contract simultaneously
Diffuse esophageal spasm
contractions proceed in a coordinated manner but the amplitude is excessive.
Nutcracker esophagus
bleeding from tears in the mucosa at the junction of the stomach and esophagus
Mallory-Weiss syndrome
The tear involves mucosa and submucosa but not the muscular layer.
Usually caused by severe coughing, retching or vomiting.
Mallory-Weiss tear
full thickness tear or rupture of the esophageal wall that can occur as a consequence of severe retching or vomiting.
Boerhaave’s Syndrome
condition characterized by mucosal damage to the esophageal lining due to stomach acid reaching the esophagus.
GERD
autoimmune disorder of the small intestine caused by a reaction to gliadin, a gluten protein found in wheat and other common grains such as barley and rye.
Celiac dz
leads to villous atrophy (shortening of the villi lining the small intestine).
celiac dz
can affect any part of the gastrointestinal tract from mouth to anus (skip lesions), although a majority of the cases start in the terminal ileum.
Crohn’s
is restricted to the colon and the rectum.
ulcerative colitis
Microscopically, … is restricted to the mucosa while …. affects the whole bowel wall (“transmural lesions”).
ulcerative colitis / crohn’s
Most common cause of viral enteritis
Norwalk virus