GI Flashcards

0
Q

characterized by increased tone and pressure at the lower esophageal sphincter (LES), diminished to absent peristalsis in the distal portion of the esophagus and lack of a coordinated LES relaxation in response to swallowing.

A

Achalasia

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1
Q

4 esophageal motility disorders

A

Achalasia, diffuse esophageal spasm, nutcracker esophagus and hypertensive lower esophageal spasm

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2
Q

lymphocytic infiltration of Auerbach’s plexus and destruction of ganglion cells is likely the underlying pathophysiology that results in this condition.

A

Achalasia

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3
Q

contractions are uncoordinated and several segments of the esophagus contract simultaneously

A

Diffuse esophageal spasm

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4
Q

contractions proceed in a coordinated manner but the amplitude is excessive.

A

Nutcracker esophagus

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5
Q

bleeding from tears in the mucosa at the junction of the stomach and esophagus

A

Mallory-Weiss syndrome

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6
Q

The tear involves mucosa and submucosa but not the muscular layer.
Usually caused by severe coughing, retching or vomiting.

A

Mallory-Weiss tear

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7
Q

full thickness tear or rupture of the esophageal wall that can occur as a consequence of severe retching or vomiting.

A

Boerhaave’s Syndrome

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8
Q

condition characterized by mucosal damage to the esophageal lining due to stomach acid reaching the esophagus.

A

GERD

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9
Q

autoimmune disorder of the small intestine caused by a reaction to gliadin, a gluten protein found in wheat and other common grains such as barley and rye.

A

Celiac dz

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10
Q

leads to villous atrophy (shortening of the villi lining the small intestine).

A

celiac dz

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11
Q

can affect any part of the gastrointestinal tract from mouth to anus (skip lesions), although a majority of the cases start in the terminal ileum.

A

Crohn’s

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12
Q

is restricted to the colon and the rectum.

A

ulcerative colitis

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13
Q

Microscopically, … is restricted to the mucosa while …. affects the whole bowel wall (“transmural lesions”).

A

ulcerative colitis / crohn’s

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14
Q

Most common cause of viral enteritis

A

Norwalk virus

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15
Q

Most common cause of severe diarrhea in infants and young children

A

rotovirus

16
Q

picnic food poisoning

A

staph aureus

17
Q

chinese restaurant food poisoning

A

b. cereus

18
Q

food poisoning from salt water crabs and shrimp

A

vibrio

19
Q

canned fruits and veggies food poisoning

A

botulism

20
Q

an autosomal dominant disorder characterized by mucocutaneous pigmentation (i.e. lesions on the face, lips, and buccal mucosa) and benign GI hamartomas.

A

Peutz-Jeghers syndrome

21
Q

Histologically, the lesions seen in …. feature a distinctive frond-like appearance with a stromal/smooth muscle core that is covered by acinar glands and normal mucosa. Nuclear atypia is absent.

A

puetz-jeghers

22
Q

(benign/pre-malignant/malignant) hyperplastic polyp

A

benign

23
Q

(benign/pre-malignant/malignant) tubular adenoma

A

pre-malignant

24
Q

(benign/pre-malignant/malignant) colorectal adenocarcinoma

A

malignant

25
Q

Most common type of poyp in the colon

A

hyperplastic

26
Q

glands that are more irregular and contain darker and more crowded nuclei. This neoplasm is benign and well-differentiated, as it still closely resembles the normal colonic structure.

A

adenomatous polyp

27
Q

polyp that is stalk-like

A

adenomatous polyp

28
Q

sessile polyp

A

villouos adenoma

29
Q

tubular adenoma

A

adenomatous polyp

30
Q

characterized by the appearance of multiple polyps in the gastrointestinal tract, usually in a child, adolescent or young adult.

A

Juvenile polyposis syndrome

31
Q

While the majority of the polyps found in … are non-neoplastic, hamartomatous, self-limiting and benign, there is an increased risk of developing adenocarcinoma.

A

Juvenile Polyposis Syndrome

32
Q

an inherited condition in which hundreds to thousands of polyps form mainly in the epithelium of the large intestine.

A

Familial adenomatous polyposis

33
Q

While these polyps start out benign, malignant transformation into colon cancer occurs when not treated

A

Familial adenomatous polyposis

34
Q

The combination of polyposis, osteomas, fibromas and sebaceous cysts is termed

A

Gardner’s Syndrome