Quiz 4: Endocrine System Flashcards
What is the endocrine system?
- A complex network of glands that produce and secrete hormones directly into the circulatory system (blood stream)
- Hormones act as chemical messengers that regular a vast array of physiological functions, from metabolism and growth to mood and reproductive system
- Operates in conjunction with nervous system
Comparison between the endocrine and nervous system
- The nervous system is quicker, but the endocrine system effects last longer
Negative Feedback system
- Most prevalent feedback mechanism
- Once a particular process reaches its desired end, it sends a signal to halt or reduce the production of the initiating hormone
Example: When blood glucose levels rise, the pancreas secrets insulin. As glucose is taken up by cells and blood glucose levels decline, insulin secretion diminishes.
Positive Feedback
- Amplify initiating stimulus which is less common
Example: LH leading to ovulation in menstrual cycle.
Hypothalamic-Pituitary-Thyroid Axis (HPT)
- Negative feedback loop that regulates metabolic rate, energy production, and overall growth
- Hypothalamus Released TRH -> Signals Pituitary gland to release TSH -> Stimulates the thyroid gland to produce T3 and T4 -> Inhibits release of TRH and TSH creating a negative feedback loop.
Hypothalamic-Pituitary-Gonadal axis
Hypothalamic-Pituitary-Adrenal Axis
Regulates digestion, immune response, energy storage, and stress response
Renin Angiotensin system
Regulates BP and fluid balance. When BP drops, the kidneys release renin
What are synergistic Interactions
- When two or more hormones producing a combined effect that is greater than their individual effect
What are Antagonistic Interactions?
When hormones counteract each other
What are permissive interactions?
A hormone facilitates the action of another hormone by creating an environment where the latter can exert its effects more effectively
What are Tropic hormones?
- Primary function is to regulate the secretion of other hormones
What are Hormonal cascades?
- Secretion of one hormone is the result of a series of hormonal interactions
What is the hypothalamus?
- Located in the brain, this gland controls many of the body’s hormonal functions by regulating pituitary gland.
- links endocrine and nervous system to work in synergy.
What is the pituitary gland?
•” master gland”
-secretes hormones that influence other endocrine glands,
-roles in growth,
What is the thyroid gland?
• Situated in the neck
- regulates metabolism, energy production and calcium balance.
- secretes T4 and T3
What is the adrenal gland?
•positioned atop the kidneys
- produces cortisol and aldosterone
What is the pancreas?
•vital for glucose regulation secreting insulin and glucagon
What are the gonads?
- Testes in males
-ovaries in females
-responsible for sex hormones
What is the thymus?
Responsible for maturation of T lymphocytes
What is the pineal gland?
Regulates sleep and circadian rhythm.
Hormones that play a crucial role in bone metabolism
1) Parathyroid
2) Calcitonin
3) Growth Hormone
Hormones that are crucial for muscle function and growth
1) Testosterone
2) Growth Hormone
3) Insulin
Hormones responsible for energy and fatigue
1) Thyroid hormones