Quiz 4-5 Flashcards
4 changes that constitute toxic change
Dohle Bodies
Basophilia
Azuorphilic Granules
Cytoplasmic Vacuoles
A degenerative left shift means there is a ___ to normal WBC count with ___% band neutrophils
low
> or equal to 10%
Neutrophils that are right shift are ____. They are characterized by having ___ or more lobes. List one cause of right shift neutrophils
Hypersegmented
5
not doing a blood film in an appropriate amount of time
The defining cell in inflammation is the
Band neutrophil
Mott cells are a common finding in dogs (T/F)
False
List 2 things that are commonly seen in monocytles in dogs that have IMHA
Hemosiden
Erythrophagocytosis
A lymphocyte with basophilic cytoplasm and a perinuclear halo would be a _____ lymphocyte
Reactive
Platelets are Cytoplamic fragments of what cell?
Megakaryocyte
2 Mechanisms of platelet formation are
Budding
Cytoplasmic Demarcation
Whatis the hormone that stimulates the production of platelets
Free TPO
What cell in birds has an eccentric nucleus, basophilic cytoplasm, and a perinuclear halo?
Plasma Cell
Neovascularization
Platelet derived growth factor
Stimulated by traumatic venipuncture
tissue thromboplasin
Factors of extrinsic
tissue thromboplasin, VII
Vit. K dependent factors
II, VII, IX, X
Substances of common pathway
Prothrombin, Thrombin, Fibrin, Fibrinogen
Produced by endothelial cells and platelets
VWF, VIII
Factors fo intrinsic
VIII, IX, XI, XII
End product of extrinsic and intrinsic
Prothrombinase
Active substance that breaks down clots
Plasmin
Aggregation
TXA
Blocks thrombin and inhibits platelets
FDPs
Stimulates and amplifies secondary hemostasis
PF3
3 Sub parts of the platelet plug
Adhesion
Aggregation
Secretion
What organ produces most of the coagulation factors
liver
What are the 3 componenets of hemostasis & which one forms the platelet plug
Primary*
Secondary
Fibrolysis
What 2 substances are made by endothelial cells and platelets
VWB Factor
Factor 8
Inflammatory
Bacterial Products ^-Neutros ^-Bands N-Lymphs ^-Monos N-Eos N-Basos
Stress
Glucocorticoids ^-Neutrophils N-Bands v-Lymphs ^-Monos v-Eos N-Basos
Physiologic
Epinephrine ^-Neutros N-Bands ^-Lymphs ^-Monos ^-Eos ^-Basos
