Quiz 4 Flashcards
_________: ⇓ WBC, due to viral infection; most commonly ________ or ________
leukopenia
neutrophils
lymphocytes
__________: ⇑ WBC, Dohle bodies: pale blue, cytoplasmic inclusion due to infection.
May be associated with ________reaction where WBS count is greater than 50,000 per ul
leukocytosis
leukomoid
__________: malignant tumor of hematopoetic stem cells in the bone marrow; mainly in the vertebrae, ribs, sternum and pelvis.
leukemia
_____: Children age 1-10; MC in children, has good prognosis with children between 2 - 10 years of age.
Has the best prognosis
ALL (Acute lymphocytic leukemia)
_____: age 40-60; 40-60 year old presence of Philadelphia chromosome in the bone marrow
CML (Chronic myelocytic leukemia)
______: age 15-40 MC in adult age, blast cells, Auer bodies, very poor prognosis, most common acute leukemia in adults, chloroma in the head, neck and bowel.
The worst kind
AML (Acute myelocytic leukemia)
_____: over 60 of age; MC in old people, 100% mature lymphocyte cells in blood smear. there’s an increase in the likelihood of hemolytic anemia.
CLL (Chronic lymphocytic leukemia)
Common features of ________:
• diffuse WBC masses in bone marrow causes pain in
vertebra, sternum, ribs & pelvis
• hepatosplenomegaly, lymphadenopathy
• anemia, ⇓ platelets, susceptibility to infection
• Acute: MC, progressive, more blast cells > 30%
• Chronic: mix with mature & immature cells
leukemia
Hodgkin’s lymphoma (________ fever)
(disease): malignant, has Reed Sternberg cells (neoplastic cells, owl-eye appearance, ⇑# with ⇑age) White > black people; inflamatory response, spreads by ________
Pel-Ebstein
contiguity
____________ lymphoma:
• Unassociated with Reed Sternberg cells
• lymphadenopathy
• hepatosplenomegaly
Non-Hodgkin’s
________ lymphoma: due to EBV (Epstein Barr virus), activates B- cells, in Africa (mandible or maxilla), in the US (abdominal), in Asia (nasopharyngeal carcinoma); “starry sky” appearance
Burkitt’s
MULTIPLE MYELOMA
• It is the MC type of primary tumor of the _____ and most common malignant plasma cell disorder
• leads to ⇑ ⇑ immunoglobulin (_____)
• MC in male (3:2), blacks & peak age of 50-70 years
bone
IgG
Multiple myeloma:
Path: punched out defect in the bone such as skull, vertebra
Nervous: vertebral compression fractures leads to neuropathy
Clinical & lab: anemia, bone pain & fracture, ⇑ Ca, __________protein (M- protein) in urine & blood, RBC stacking in _______
Bence-Jones
rouleaux
- All of the following are clinical features of multiple myeloma EXCEPT:
A. Increase serum calcium
B. Bence-Jones proteinuria
C. Circular (punched out) osteolytic lesions commonly seen in skull X-ray
D. Bone marrow smears containing decreased plasma cell numbers
E. Recurrent infection
D. Bone marrow smears containing decreased plasma cell numbers
66. The most common type of leukemia found in children under the age of 15 years is: A. Acute myelocytic leukemia B. Acute lymphocytic leukemia C. Chronic lymphocytic leukemia D. Chronic myelocytic leukemia E. Hairy cell leukemia
B. Acute lymphocytic leukemia
