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Systemic Pathology > Quiz 1 > Flashcards

Quiz 1 Flashcards

1
Q

Multifocal, granulomatous inflammation of the temporal
artery and/or external carotid arteries in female patients over 50 years old, the granuloma contains multinucleated giant cells sometimes accompanied by Polymyalgia rheumatica (pain & stiffness of the neck & shoulders)

A

Temporal arteritis (giant cell arteritis)

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2
Q

“Pulseless disease” cell mediated allergy (type4) causing
granulomatous inflammation of the aortic arch and HLA
•leading to fibrosis of the tunica media and weak pulse especially in the upper extremities.
•Weak pulse and low BP

A

Takayasu’s arteritis

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3
Q

necrotizing inflammation of small & medium arteries due to immune complex deposition (type 3 allergy)
•Male middle age.
•Causing irregular aneurysmal dilatation, nodular swelling of the vessels of some organs (kidney, heart, EXCEPT lungs), leading to vascular obstruction & organ infarction
•Most common cause of death is renal failure

A

Polyarteritis Nodosa (PAN)

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4
Q

•Necrotizing granulomatous inflammation of the small to medium sized arteries (veins or capillaries) of the lungs & kidneys
•Male middle age
•Due to immune complex (Type … allergy)
•hemoptysis & hematuria
•Lab: anti- neutrophil cytoplasmic antibodies
(ANCA) or (C-ANA)

A

Wegener’s granulomatosis

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5
Q

•Inflammation of the small vessels, affects mainly the skin.
•2 types:
•1. Henoch-Schonlein purpura: palpable bleeding under the skin, hematuria, arthritis of the children
**2. Churg-Strauss syndrome : asthma in young person, vasculitis, & eosinophilia

A

Hypersensitivity angitis

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6
Q

Henoch-Schonlein purpura

A

palpable bleeding under the skin, hematuria, arthritis of the children

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7
Q

Churg-Strauss syndrome

A

asthma in young person, vasculitis, & eosinophilia

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8
Q

Broken capillaries that elevate the skin are called _________.

A

Purpura

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9
Q
  • YOUNG , MALE, SMOKERS, certain area (India, Japan…)
  • vasculitis of tibial & radial arteries
  • may cause gangrene
A

Thromboangiitis Obliterans (Buerger’s disease)

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10
Q
  • Vasospasm of small arteries in hands & feet
  • MC in young Female
  • very rare causes gangrene
A

Raynaud’s disease

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11
Q
  • A febrile illness (arteritis) often the coronary arteries
  • MC in children younger than 4 years old
  • It is the leading cause of acquired heart disease in children in the US
A

Kawasaki’s disease

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12
Q
  • MC in veins (legs)

* Varicose veins

A

Thrombophlebitis

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13
Q

•dilated, tortuous veins, MC female, family history, pain, bleeding,…lead to stasis dermatitis

A

Varicose veins

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14
Q
  • cellulitis with red streak to the lymph nodes

* severe pain

A

Acute lymphangitis

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15
Q

Interstitial fluid accumulation due to lymphatic obstruction, non- pitting edema MC after surgery

A

Lymphedema

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16
Q

Atheroma= fibrofatty plaques in the tunica intima (endothelium) Most common Cause: Age, Family, increase in LDL, hypertension, smoking, diabetes, obese, stress

A

Atherosclerosis

17
Q

•affects intima & media of small arteries with old age,
diabetes, hypertension
•mainly renal arterioles causes narrowing of the
lumen
•is under the umbrella of Arteriolosclerosis

A

Hyaline arteriolosclerosis

18
Q
  • is under the umbrella of Arteriolosclerosis
  • with severe hypertension Diastolic >120 mmHg
  • affects small arteries of kidney, intestine & ..
  • affects intima causes concentric laminated (onion ring) thickness of the wall
A

Hperplastic arteriolosclerosis

19
Q
  • Affects T. media of small & medium sized a. causes hard like a rock & tortuous
  • Elderly Male
  • X-ray = calcifications
A

Monckeberg’s medial calcific sclerosis

20
Q

• Abnormal dilatation that can be Atherosclerotic

A

Aneurysm

21
Q
  • endarteritis obliterans
  • Aortic regurgitation
  • Water Hammer pulse
A

Syphilitic aneurysm

22
Q
  • most likely in the Circle of Willis
  • young age
  • Due to congenital disease
  • associated with:polycystic, coarctation,
  • subarachnoid hemorrhage
A

Berry aneurysm

23
Q

a vascular tumor that is:
•benign, uncapsulated (not capsulated) tumor
•bright red, mainly cosmetic disturbance

A

Capillary hemangioma

24
Q

benign, uncapsulated tumor of large cavernous blood

spaces. red-blue,if it affects the cerebellum, called: Lindau- Von Hippel disease

A

Cavernous hemangioma

25
Q

•abnormal dilatation of small vessels (arterioles or capillaries)
• 2 types:
a. spider naevi: arterioles, associated with pregnancy or liver cirrhosis
b. Nevus flammus (birth markers): at birth & fade away.

A

Vascular ectasis (telangiectasis)

26
Q

malignant vascular tumor that affects the skin, breast & liver

A

Angiosarcomas

27
Q
  • Dilated vascular spaces causing petichae
  • nodular lesions
  • associated with AIDS & aggressive
A

Kaposi’s sarcoma

Systemic Pathology (11 decks)

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