Quiz 3 Flashcards
What is the extracellular component of blood called?
plasma
3 types of cells in blood
Erythocytes, Leukocytes, platelets
What kind of tissue is blood
connective tissue
water, protein, and other solutes individually make up what percentage of blood plasma?
blood-92 protein 7 other solutes 1
Normal Hematocrit Range
35-49%
Hemoglobin
13.5-17.5 gm/100mL
Na+
135-145 mEq/L
K+
3.5-5.1 mEq.L
HCO3-
22-29 mEq/L
Cl-
98-106 mEq/L
Ca++
8.4-10.2 mg/100ml (dL)
Fasting Glucose
75-115 mg/100 ml (dL)
Normal Erythrocyte range for Male
4.3-5.7 *(10^6)
Normal Erythrocyte range for Female
3.9-5.0 * (10^6)
Leukocyte range
4-10*(10^3)
what percentage of leukocytes are Neutrophils
50-70%
what percentage of leukocytes are Eosinophils
2-5%
what percentage of leukocytes are Basophils
0-1%
what percentage of leukocytes are Lymphocytes
20-50%
what percentage of leukocytes are Monocytes
3-8%
What is normal platelet range
150-450*(10^3)
all sensory axons are derived from
neural crest cells
all Schwann cells are derived from
neural crest cells
Brain receives what percentage of total cardiac output
20%
Brain contains how many neurons
100 billion
Are there more glial cells or neurons?
glial cells
How many spinal nerves
31
How many cranial nerves
12
cranial and dorsal root ganglia are cell bodies of what kind of nerves?
sensory
What are autonomic ganglia
cell bodies of autonomic postganglionic nerve fibers
Where do all of the postganglionic autonomic nerves derive from
neural crest cells
What are motor nerve fibers derived from?
the neural tube
What are all preganglionic autonomic nerve fibers derived from
the neural tube
What is the perikaryon
cell body of neuron
What is Nissl
large amount of rough ER and polyribosomes
What is soma
cell body of neuron
How does the cytoplasm of a neuron stain? basoophilic or eosinophilic and why
basophilic lots of ER and polyribosomes
Most neurons are unipolar, multipolar, bi polar, pseudounipolar?
multipolar
What does multipolar mean
lots of dendrites with one single axon
Slow axonal transport is what speed
0.2-4 mm/day
fast axonal transport is what speed
20-400 mm/day
What are the tree kinds of synapses
axodendritic axosomatic axoaxonic
What are the two main types of neuron receptors
ligand-gated ion channels Metabotropic receptors
What are the tree ways that neurotransmiter action is terminated by?
enzymatic degradation diffusion reuptake into terminal
are sensory neurons multipolar, unipolar, pseudounipolar, bipolar?
pseudounipolar
What kind of cells make myelin in the CNS and PNS
oligodendrocytes schwann cells
What is rate of axon regeneration
1-2 mm per day
speed of an axon is dependent on what two things
diameter and thickness of myelin sheath
What do Meissner’s corpuscle do?
sensory specializations that transduce touch
What are Pacinian corpuscles?
specialized receptor with a sensory nerve fiber at it’s core that is specialized to detect deep pressure and vibration
Nerve free endings sense what two things
pain, temperature
how are nerve free endings stained?
immunohistological techniques
All of the central nervous system deveopes from the sigle layer of __ __ that make up the neural tube
neuroepithelial cells
around how many neurons
100 billion
how many synapses
10^15
How many glia per neuron?
10
Glia are categorized into what two major divisions
-macroglia -microglia
macroglia arise from: microglea arise from:
-neuroeptithelium of neural tube -mesodermal, macrophage monocyte system/ myeloid precursor
What are 3 types of macroglia
astrocytes, oligodendroctes, and ependymal cells
What do astrocytes do 4
1) maintain normal interstitial environment, 2) remove excess ions and neurotransmitters, 3)make growth factors, 4) induce formation of blood brain barrier.
Waht do oligodendrocytes do?
make myelin in CNS
What do ependymal cells do?
line brain ventricles and central canal of spinal cord
What does choroid plexus do?
modified ependymal cells that produce CSF
What do microglia do?
phagocytic properteis
What are the two appearances of astorcyte processes
protoplasmic (fleshy) and fibrous (thin)
formation of the blood brain barrier is induced by what?
astrocytes
t/f one oligodendrocyte can myelinate many axons
T
one oligodendrocyte can myelinate segments of __ to ___ axons in the regions
8 to 10
multiple sclerosis identifies what kind of myelin–CNS/PNS
CNS
What controls the composition of CSF
choroid plexus epithelial cells
for choroid epithelial cells microvillare are on what side?
CSF side
do ependymal cells in central canal of spinal cord have microvilli or cilia?
cilia
blood csf barrier is made up of
choroid epithelial cells
capillaries are separated from ventricle lumenbut what shape/classification of epithelial cells
cuboidal epithelium
choroid plexus cells manufacture spinal fulid via ___ ___ from the capillaries
selective transport
t/f microglia are antigen present cells
t
Dura is made up what kind of connective tissue
dense irregular collagenous
Arachnoid is made up what kind of connective tissue
Loose CT b/w 2 layers of simple squamous
Pia is made up what kind of connective tissue
layer of simple squamos, loose CT
What are the two major categories of anemia
red cell morphology and hemolysis/hemorrhage
What is a reticulocyte
final sate of red cell maturation
What are hte 5 types of leukocytes
neutrophils eosinophils basophils lymphocutes monocytes
What are leukocytes that are granulocytes
neutrophils eosinophils basophils
What are agranulocytes
lymphocytes monocytes
What is the difference between granulocytes and agranulocytes
agranulocytes do not have specific granules , but both have azurophilic granules
What is this?
neutrophil
What is this?
Eosinophil
What is this?
basophil
What is this
lymphocyte
What is this?
monocyte
Which leukocyte produces major basic protein
eosinophil
What responses is major basic protein a part of
allergic and parasitic
What two important molecules do basophils contain
heparin and histamine
major job of neutrophils
phagocytosis
which leukocyte is the largest
monocyte
When monocytes leave hte blood stream and enter the tissues they become
macrophages
What are platelets derived from?
the cytoplasm of the megakaryocytes
Which leukocyte contains cat eye like granules
eosinophils
what is the platelet’s source of energy?
glycogen
What is size of erythrocyte?
7-8 microns
platelets are what size?
2-3 microns
Which leukocyte is least prevalent in blood
basophils
tunic intima contains what 2 things ?
endothelum and internal elastic lamina
tunic media contains what 2 things ?
smooth muscle and external elastic lamina
adventitia is outside of
external elastic lamina
What is the largest portion of an artery
tunica media
Between the arterioles and the capillaries there are ____which ha eonly one layer of ___ ____ which is often _____.
metarterioles
smooth muscle
discontinuous
size of capillary
9-12 microns
3 types of capillaries
continuous
fenestrated
discontinuous
Where are continuous caps found?
muscle,brain, lung, bone
Where are fenestrated caps found?
gut, endocrine, kidney
Where are discontinuous caps found?
liver, bone marrow, spleen
What is another name for a discontinuous cap?
sinusoid
What are 2 functions of pericytes
regenterative/stem cell and contractile
What is dominant layer in veins?
adventita
T/flymphatics have a complete basement membrane
f