quiz 2 Flashcards
immune response that does not involve memory; nonspecific manner; not confer long-lasting or protective immunity to host; immediate defense against infection
innate response
foreign substances- proteins, often microorganisms and their toxins; human cells that have been transformed- tumor cells or cells infected with viruses; organ transplants
antigen
tissues from the persons own body becomes an antigen
autoimmune disease
what are the primary wbcs involved in immune response
lymphocytes
cellular involvement in the immune response
b, t lymphocytes, macrophages, cytokines
cells that are able to recognize and respond to an antigen; derived from precursor cells in bone marrow(stem cells)
lymphocytes; constitute 20 to 25% of the wbc population
two main types of lymphocytes
b and T
can destroy cells recognized as foreign without recognizing specific antigens(innate immunity)
natural killer cells
develop and reside in lymphoid tissue; travel to the site of injury when stimulated by antigen
b lymphocytes
two main types of B lymphocytes
plasma cells and b memory cells
produce specific antibodies that are categorized into 5 classes of immunoglobulines, which are carried in blood serum
plasma cells
retains the memory of previously encountered antigen and will clone itself in the presence of antigen
b memory cell
antigen combined with antibody
immune complex
travel to thymus and mature; thymus is large in infant and shrinks as the child matures
t lymphocytes
similar to B memory cells
memory cells
increase functioning of b lymphocytes (enhance the antibody response) t4 cell marker
t helper cell
directly attacks virally infected cells or tumor cells/ t8 cell marker
t cytotoxic cells
active in phagocytosis of foreign material; can act as antigen presenting cells. can stimulate the lymphocytes to travel from lymphoid tissue to the injury site. links inflammatory response and the immune response together; produce cytokines called monokines
macrophages