extra point quiz Flashcards

1
Q

oral cancer is the __ most common type in men and the __ most common type in women

A

8th;14th

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2
Q

the death rate of oral cancer is approximately __ death every hour, every day

A

one

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3
Q

_______ accounts for 40% of all cancers in india

A

squamous cell carcinoma

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4
Q

in india, approx __ people die every hour of oral cancer alone

A

14

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5
Q

____ per year will die

A

9,000

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6
Q

the average survival rate at 5 years is ____%(blacks 39% vs whites___%)

A

59%; 61%

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7
Q

oral cancer has the ____ lowest survival rate of any cancer. and survival rates alone are not improving

A

5th lowest

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8
Q

____ new cases of oral and oropharyngeal cancer diagnosed in the US in 2010

A

36,540(more in men than women)

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9
Q

the cdc states that the 5-year survival rate for patients with localized disease is ___%`

A

81

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10
Q

however, the 5-year survival rate for patients with oral cancer spread to other sites is only ___%

A

30

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11
Q

_______ makes up over 90% of all oral and oropharyngeal cancers

A

squamous cell carcinoma

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12
Q

peak age is 50-70 yrs old; no age is immune; male prediction 3-1; oral cancer has been found in 2 yr olds; risk factors correlate with incidence in the >40 year old group

A

squamous cell carcinoma

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13
Q

____men have the highest overall incidence rate of oral squamous cell carcinoma and blacks and whites have higher oral cancer rates than do hispanics or asians

A

black men

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14
Q

___ is the most common site of oscc for all ethniticites

A

tongue

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15
Q

there has been a fourfold increase in occurrence in men in their 30’s as compared to 10 years ago in what cancer

A

oscc

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16
Q
risk factors: 
tobacco
alcohol
genetic defects
immune defects
environmental defects
betel quid, areca nut, narcotics, and cannabis use
hpv
A

squamous cell carcinoma

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17
Q

how much percent of those with oral cancer were/is a smoker

A

90%

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18
Q

smokers are __ times more likely to develop oral cancers than nonsmokers

A

6

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19
Q

cigarette smoke destroys the antioxidants in the saliva and turns the saliva into a chemical mixture that could

A

accelerate the development of mouth cancer

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20
Q

is smokeless tobacco a huge risk factor as previously though?

A

no

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21
Q

moist or dry leaf is worse?(smokeless tobacco)

A

dry

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22
Q

in sweden, there is an ___ in smokeless tobacco usage but a decrease in the incidence of oral cancer

A

increase

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23
Q

oral cancer will usually appear about ____ years after smokeless tobacco use

A

20-40 years

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24
Q

it truly takes ___ weeks for tobacco pouch keratosis to resolve

A

2-6 weeks

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25
Q

biopsy if lesion persists after __ weeks without contact with tobacco

A

6

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26
Q

pacific islanders and asians are bringing a dangerous habit with them to the us; treating it like smokeless tobacco

A

betal nut quid

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27
Q

an addictive stimulant that can cause an aggressive form of oral cancer

A

betel leaf

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28
Q

swedish style, steam-pasteurized, moist smokeless tobacco; not dry or fire-cured like snuff; not a good idea; if these carcinogens are swallowed, , will it increase the numbers of esophageal and stomach cancers?

A

snus

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29
Q

defined as drinking 6 equivalents or more per day of : 1.5 oz hard liquor(shot)
6oz. wine
12oz beer

A

alcohol abuse

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30
Q

you are at greater risk of oral cancer if you abuse__ than if you are smoking 2 packs per day

A

alcohol

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31
Q

six drinks/day=__ times increase risk of cancer

A

3.3

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32
Q

6-9 drinks/day= ___ times increase risk

A

15

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33
Q

aging
chronic nutritional deficiency
disease states
therapeutic intervention

A

immune system deficits

34
Q

low consumption of fruits and veggies ___ an oral cancer risk factor

A

is

35
Q

can result in gradual accumulation of genetic defects which alters the cell’s ability to regulate normal cell function; aids, chronic candida, hpv, some types of herpes virus(herpes cofactor with tobacco)

A

disease states

36
Q

some studies suggest oral cancers at the base of the ___ and ____ are associated with high risk hpv types oropharyngeal cancers

A

tongue; tonsils

37
Q

how do some hpvs promote malignant transformation?

A

by inactivation of certain oncosuppressor genes

38
Q

hpv vaccines cover teh hpv___ found most commonly in the oral mucosa, but their protective effect against oral cancer remains to be elucidated

A

genotypes

39
Q

oral and oropharyngeal scc has been linked to high-risk ___ strains

A

hpv

40
Q

oral hpv infection may be transmitted

A

sexually
mouth to mouth
vertically from an infected mother to her newborn during delivary

41
Q

if your immune systems surveillance is removed this can increase the risk for

A

cancer

42
Q

is family history of cancer a risk factor for squamous cell carcinoma

A

no

43
Q

is consumption of hot beverages and spicy foods a risk factor

A

no

44
Q

south carolina has the __ highest oral cancer mortality rate in the US

A

4th

45
Q

persons with chronic gum disease were __ times more likely to have tongue cancer with every millimeter of alveolar bone loss than those without gum disease

A

5.2 times

46
Q
red plaque-like(or mixed)
white plaque
ulcer
exophytic mass(can be endophytic)
irregular, nodular mass
unexplained radiolucency
A

squamous cell carcinoma

47
Q

a red lesion of the oral mucosa with no apparent cause; also should be carefully evaluated especially if there is history of tobacco usage

A

erythroplasia

48
Q

caused by epithelial dysplasia, cis, or scc; middle-aged; risk factors important; floor of mouth, lateral and ventral tongue, soft palate; biopsy mandatory if lesion persists after removal of suspected predisposing factors

A

erythroplakia

49
Q

__ are already dysplasia, cis, or scc

A

91% of erythroplakia

50
Q

what is the most common precancerous lesions of the oral mucosa

A

leukoplakia and erythroplasia

51
Q

heterogeneous and homo

A

leukoplakia

52
Q

lack of uniformity

A

hetero

53
Q

uniform appearance

A

homo

54
Q

clinical diagnosis, not microscopic; asses rf; increased risk for malignant transformation; biopsy mandatory if lesion persists after removal of suspected predisposing factors

A

leukoplakia

55
Q

leukoplakia: dysplasia in about __% of cases, invasive scc in __ % of cases

A

10;5

56
Q

red lesion with focal areas of white plaques; biopsy mandatory if lesion persists after removal of suspected predisposing factor; high incidence of premalignancy or malignancy with this type

A

speckled leukoplakia

57
Q

what kind of feature is pain

A

late feature

58
Q

unusual sites of scc

A

dorsum of tongue and rugae

59
Q

hard, nonmovable lesions, irregular borders, nonhealing ulcer, pain

A

advanced lesions scc

60
Q

sites at greater risk for scc

A

posterior lateral border of tongue, floor of mouth-epithelium is thin/occurs in males mostly; tonsillar pillars

61
Q

5 year survival rate of oral cancer

A

> 80% for early stage

20% with advanced stage

62
Q

stage 1

A

77-85%

63
Q

stage 2

A

66-76%

64
Q

stage 3

A

41-44%

65
Q

stage 4

A

9-20%

66
Q

is histological differentiation of importance to prognosis of scc

A

least importance

67
Q

there is an increased incidence of scc in young

A

adults; poor survival rate; deficit in immune system or related to marijuana use

68
Q

light-emitting diode(led light that provides blue-white illumination of lesions after applying 1% acetic acid wash. examples: microlux/dl and orascoptic dk. abnormal squamous epithelium appears distinctly white

A

tissue-reflectance devices

69
Q

uses blue light to distinguish healthy mucosa from malignant oral tissue. example: velscope, abnormal tissue appears darker than the pale green background of normal tissue

A

autofluorescence device detector

70
Q

one product combines the technologies of tissue reflectance and autofluorescence with a white light source. ex: identafi 3000

A

autofluorescence-tissue reflectance device

71
Q

using toluene blue stain, brush-cytology sampling provides a full-thickness sample of cells from the lesion. helps the practitioner assess the need for surgical biopsy and tissue diagnosis. ex: cytobrush plus gt

A

lesion-sampling device

72
Q

an aggressive form of oral leukoplakia: persistent, often multifocal, refractory of treatment, high risk of recurrence and high risk of malignant transformation

A

pvl

73
Q

has a higher risk of malignant transfromation than the most common non-verrucous leukoplakis

A

pvl

74
Q

females middle-aged-eldery; hard palate and gingiva; could develop into verrucous carcinoma or well-diff scc

A

pvl

75
Q

___ % of patients will die with pvl associated cancers

A

40%

76
Q

even with aggressive surgical excision, __% of lesions pvl will be cancerous in 10 yrs

A

70%

77
Q

shaggy and raised; slow growing and low metastatic rate. 74% survival rate

A

verrucous carcinoma

78
Q

every patient 18 yrs of age or older shoul dbe

A

screened 1x/year

79
Q

high risk patients should be screened every

A

6 months

80
Q

__% of incidence of oral scc found among patients who had never smoked according to one study

A

33%