Quiz 2 Flashcards

1
Q

What is TRUE regarding the biochemical uses of B1:
Question 1 Answer

a.
It works in a redox capacity and plugs into the electron transport chain (ETC)

b.
It transfers CoA to various molecules involved in energy production

c.
It works with B2, B3 and B5 in the pyruvate dehydrogenase reaction

d.
It is a coenzyme for transaldolase in the pentose phosphate shunt

A

c.
It works with B2, B3 and B5 in the pyruvate dehydrogenase reaction

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2
Q

Which of the following is TRUE of B-vitamins:
Question 2 Answer

a.
They may use phosphatases to help facilitate absorption

b.
They are typically stored in significant amounts prior to urinary excretion

c.
They require frequent dosing of small amounts to reduce chance of toxicity

d.
They may undergo cleavage to release the active coenzyme form

A

a.
They may use phosphatases to help facilitate absorption

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3
Q

Which of the following is TRUE regarding thiamin deficiency:
Question 3 Answer

a.
It predominantly affects the brain and liver, potentially causing Wernicke-Korsakoff syndrome

b.
It can be precipitated by a diet high in corn that has not been soaked in an alkaline solution

c.
It can adversely affect nerve conduction through decreased production of acetylcholine

d.
It can be caused by decreased B1 absorption due to polyphenols found in raw red meat

A

c.
It can adversely affect nerve conduction through decreased production of acetylcholine

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4
Q

Which of the following vitamin coenzyme forms are based on a nucleotide structure?
Question 4 Answer

a.
CoA, TDP, NAD+

b.
FADH2, FMN, CoA

c.
NADPH, FADH2, FMN

d.
NADPH, FADH2, TDP

A

c.
NADPH, FADH2, FMN

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5
Q

Which of the following correctly matches a synthesis pathway with the correct vitamin coenzymes:
Question 5 Answer

a.
Heme synthesis: B6, B7

b.
Synthesis of cys from ser: B5, B6

c.
Fatty acid synthesis: B2, B5

d.
Synthesis of ketones and cholesterol: B5, B6

A

a.
Heme synthesis: B6, B7

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6
Q

Which of the following would be true of a tryptophan load test done on a B6 deficient patient:
Question 6 Answer

a.
Increased production of NAD+ resulting in decreased excretion of xanthurenic acid

b.
Decreased production of NAD+ resulting in decreased excretion of xanthurenic acid

c.
Decreased production of NAD+ resulting in increased excretion of xanthurenic acid

d.
Increased production of NAD+ resulting in increased excretion of xanthurenic acid

A

c.
Decreased production of NAD+ resulting in increased excretion of xanthurenic acid

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7
Q

B6 is used to make all of the following neurotransmitters EXCEPT:
Question 7 Answer

a.
Acetylcholine

b.
Serotonin

c.
Dopamine

d.
GABA

A

a.
Acetylcholine

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8
Q

Which of the following is true regarding IF (intrinsic factor):
Question 8 Answer

a.
IF bound to B12 is internalized via receptor-mediated endocytosis

b.
IF is made in the stomach and carries B12 to the duodenum

c.
IF helps release B12 from food during the digestive process

d.
IF is made in the duodenum and protects B12 from degradation

A

a.
IF bound to B12 is internalized via receptor-mediated endocytosis

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9
Q

A Meckel diverticulum develops because ______________
Question 9 Answer

a.
the vitelline duct fails to be obliterated.

b.
the foregut fails to re-canalize.

c.
the intestines fail to return to the body cavity.

d.
the ventral body wall fails to close.

A

a.
the vitelline duct fails to be obliterated

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10
Q

Which of the following congenital malformations is associated with polyhydramnios during pregnancy?
Question 10 Answer

a.
Meckel diverticulum

b.
Congenital biliary atresia

c.
Esophageal atresia

d.
Gastroschisis

A

c.
Esophageal atresia

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11
Q

Which of the following structures is NOT derived from the foregut?
Question 11 Answer

a.
The spleen

b.
The liver

c.
The lungs

d.
The pancreas

A

a.
The spleen

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12
Q

Which of the following structures is supplied by a branch of the celiac trunk?
Question 12 Answer

a.
The first part of the jejunum

b.
The stomach

c.
The lungs

d.
The appendix

A

b.
The stomach

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