Quiz 10 Questions Flashcards
The deletion of 2 consecutive nucleotides in a DNA sequence would result in which type of mutation?
Question 1 options:
Transversion
Transition
Insertion
A frameshift mutation
Frameshift
The following DNA sequence 5’-TGCGATCC-3’ is mutated to 5’-TGCAATCC-3’.
This is an example of which type of mutation?
Question 2 options:
Transversion
Insertion
Tautomeric shift
Transition
Transition
Because tautomeric shifts are transient, they do not cause permanent mutations.
Question 3 options:
True
False
False
The movement of a hydrogen atom from one position on an organic molecule to another position on the same molecule is called a:
Question 4 options:
Transition
Frame shift
Tautomeric shift
Transversion
Tautomeric Shift
Tautomeric shifts cause mutations by:
Question 5 options:
Altering the reading frame of the DNA sequence
Rearranging the DNA sequence
Removing nucleotides
Altering the base-pairing abilities of the “shifted” nucleotide
Altering the base-pairing abilities of the “shifted” nucleotide
Which of the following is an example of a tri-nucleotide repeat expansion disease?
Question 6 options:
Huntington’s disease
Cystic fibrosis
Albinism
Xeroderma pigmentosum
More than one response is correct
Huntington’s Disease
Which of the following pieces of evidence/statements supports the concept that “Mutation is non-adaptive”?
Question 7 options:
Mutations conferring antibiotic resistance in bacteria are present before exposure to the antibiotic.
Mutations can be spontaneous or induced.
A small proportion of colonies exposed to antibiotic will survive due to the presence of an antibiotic resistance mutation.
Mutations can be inherited if they occur in germ-line cells.
Mutations conferring antibiotic resistance in bacteria are present before exposure to the antibiotic.
Which of the following is true about UV radiation and it’s ability to cause DNA mutations? Select all that apply:
Question 8 options:
It leads to the hydrolysis of cytosine
It leads the formation of thymine dimers
It causes breaks in DNA
It induces mutations through excitation
It leads the formation of thymine dimers
It causes breaks in DNA
It induces mutations through excitation
If the following fragment of a non-template (coding) DNA strand 5’-ATGCCTGAG-3’ was mutated to produce 5’-ATGCCAGAG-3’ it would result in which of the following?
Question 10 options:
A mis-sense mutation
A silent mutation
A non-sense mutation
A frameshift mutation
A silent mutation
