Question Flashcards

1
Q

What is the oldest pharmacy science s?

A

Pharmacognosy

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2
Q

Crude drug

A

Raw drug

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3
Q

What are carbohydrates?

A

Compound composed of C, H and O
Polysaccharides

(Carbon surround with H2O)

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4
Q

Primary metabolites

A

Compounds that are essential of growth and development of plants
(Plants can’t live without them)
Eg: sugars, amino acids , nucleotides and lipids

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5
Q

Secondary metabolites

A

Compounds that don’t function in growth and development of plants
* Play important role in defense against pathogens
* Attraction for pollination

Eg : tannins, alkaloids, waxes , glycosides , volatile oil and carbohydrates (pectin , gums and mucilage)

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6
Q

Gums

A

Natural plant hydrocolloids classified as polysaccharides or their salts (adhesive and viscous solution in H2O)

*They contain Mg and Ca salts of uronic acids
* T A substance produced for protection as result of injury

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7
Q

T and A

A

Colorless and Amorphous

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8
Q

Uronic acids

A

Glucose or sugar that has been oxidized

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9
Q

What is Mucilage ?

A

Sugars and uronic acids units deposited in plant cells

  • Form viscous colloidal solution in H2O non-adhesive
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10
Q

Types of mucilage?

A

Acidic mucilage: red color with ruthenium Red
Neutral mucilage: blue color with methylene blue (مفهوش uronic acids)

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11
Q

Pectin

A

The dilute acid extract of the inner of citrus fruit (🍊🍋) and apple pomace

  • Soluble in water to give a viscous, colloidal and acidic solution
    Uses : suspending agent - anti_diarrhoel formulation
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12
Q

Glycosides

A

They are composed of two parts : sugar part ( glycone )
Non- sugar part (aglycone= genin)

  • They soluble in water (the higher the sugar content, the less the solubility in organic solvent)
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13
Q

Which part of glycolysides have the therapeutic activity ?

A

Aglycone part
(Glycone is transportation of aglycone to site of action )

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14
Q

Classification of glycosides

A

Phenolic Glycosides
Thiglycosides
Cyanophore Glycosides
Steroidal Cardio active Glycosides
Saponins

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15
Q

Thiglycosides

A

Thiocyanate found widely in cruciferous plants and black mustard

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16
Q

Steroidal Cardio active Glycosides

A

They increase tone excitability of cardiac muscles
High dose cause death

17
Q

Tannins

A

Have sharp astringent taste and high MWt (1000-5000)

*Condensed tannins green color with FeCl3
* Hydrolysable tannins give blue color with FeCl3

They cause precipitation of gelatin, proteins as well as alkaloids

18
Q

What are the Uses of drug containing tannins ? 8

A
  1. Astingent for Hemorrhoids and skin abrasion
  2. Antidote for heavy metals and alkaloids poisoning
  3. Treatment of burns
  4. Leather tanning
  5. Ink preparation
  6. Antioxidant
  7. Anticancer
19
Q

Alkaloids

A

Are basic nitrogenous compounds, they occur in form salts of organic and inorganic acids (water soluble )

20
Q

Narcotic and Analgesic alkaloids

A

Morphine
Codeine

21
Q

Central stimulant alkaloids

A

Caffeine

22
Q

Mydriatic action alkaloids

A

Atropine

23
Q

Smooth muscle relaxant

A

Papaverine

24
Q

Skeleton muscle relaxant

A

Tubocurarine

25
Q

Chemical test for alkaloids

A

Mayer reagent give creamy white ppt
Dragendorff reagent give orange color

26
Q

What are waxes

A

They are esters of fatty acids
Contain large amount of free acids, hydrocarbon and sterols

27
Q

Waxes uses and origin

A

Animal: beeswax
Vegetables: carnuba wax
Used widely in industry polish and cosmetics

28
Q

Resins

A

They soft and melt on heating , insoluble in H2O but soluble in alcohol

29
Q

Volatile oil

A

Enhancing physiological conditions