Qualitative and Quantitative WBC disorders Flashcards

1
Q

Which of the following is an unusual complication
that may occur in infectious mononucleosis?
A. Splenic infarctions
B. Dactylitis
C. Hemolytic anemia
D. Giant platelets

A

C

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2
Q

In a patient with human immunodeficiency virus
(HIV) infection, one should expect to see:
A. Shift to the left in WBCs
B. Target cells
C. Reactive lymphocytes
D. Pelgeroid cells

A

C

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3
Q

Which inclusions may be seen in leukocytes?
A. Döhle bodies
B. Basophilic stippling
C. Malarial parasites
D. Howell–Jolly bodies

A

A

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4
Q

Which of the following is contained in the primary
granules of the neutrophil?
A. Lactoferrin
B. Myeloperoxidase
C. Histamine
D. Alkaline phosphatase

A

B

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5
Q

What is the typical range of relative lymphocyte
percentage in the peripheral blood smear of a
1-year-old child?
A. 1%–6%
B. 27%–33%
C. 35%–58%
D. 50%–70%

A

D

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6
Q

Qualitative and quantitative neutrophil changes
noted in response to infection include all of the
following except:
A. Neutrophilia
B. Pelgeroid hyposegmentation
C. Toxic granulation
D. Vacuolization

A

B

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7
Q

Neutropenia is present in patients with which
absolute neutrophil counts?
A. <1.5 × 109/L
B. <5.0 × 109/L
C. <10.0 × 109/L
D. <15.0 × 109/L

A

A

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8
Q

The morphological characteristic(s) associated
with the Chédiak–Higashi syndrome is (are):
A. Pale blue cytoplasmic inclusions
B. Giant lysosomal granules
C. Small, dark-staining granules and condensed nuclei
D. Nuclear hyposegmentation

A

B

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9
Q

The morphological characteristic(s) associated
with the Chédiak–Higashi syndrome is (are):
A. Pale blue cytoplasmic inclusions
B. Giant lysosomal granules
C. Small, dark-staining granules and condensed
nuclei
D. Nuclear hyposegmentation

A

C

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10
Q

SITUATION: A differential shows reactive
lymphocytes, and the physician suspects a viral
infection is the cause. What is the expected
laboratory finding in a patient with a
cytomegalovirus (CMV) infection?
A. Heterophile antibody: positive
B. Epstein–Barr virus (EBV)–immunoglobulin
(IgM): positive
C. Direct antiglobulin test (DAT): positive
D. CMV–IgM: positive

A

D

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11
Q

Neutrophil phagocytosis and particle ingestion are
associated with an increase in oxygen utilization
called respiratory burst. What are the two most
important products of this biochemical reaction?
A. Hydrogen peroxide and superoxide anion
B. Lactoferrin and NADPH oxidase
C. Cytochrome b and collagenase
D. Alkaline phosphatase and ascorbic acid

A

A

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12
Q

Which of the morphological findings are
characteristic of reactive lymphocytes?
A. High nuclear:cytoplasmic ratio
B. Prominent nucleoli
C. Basophilic cytoplasm
D. All of these options

A

D

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