Hypochromic and microcytic anemias Flashcards
The osmotic fragility test result in a patient with
thalassemia major would most likely be:
A. Increased
B. Decreased
C. Normal
D. Decreased after incubation at 37°C
B
All of the following are characteristic findings in a
patient with iron deficiency anemia except:
A. Microcytic, hypochromic red cell morphology
B. Decreased serum iron and ferritin levels
C. Decreased total iron-binding capacity (TIBC)
D. Increased RBC protoporphyrin
C
Iron deficiency anemia may be distinguished from
anemia of chronic infection by:
A. Serum iron level
B. Red cell morphology
C. Red cell indices
D. Total iron-binding capacity
D
Which anemia has red cell morphology similar to
that seen in iron deficiency anemia?
A. Sickle cell anemia
B. Thalassemia syndrome
C. Pernicious anemia
D. Hereditary spherocytosis
B
Iron deficiency anemia is characterized by:
A. Decreased plasma iron, decreased % saturation,
increased total iron-binding capacity (TIBC)
B. Decreased plasma iron, decreased plasma ferritin, normal RBC porphyrin
C. Decreased plasma iron, decreased % saturation,
decreased TIBC
D. Decreased plasma iron, increased % saturation,
decreased TIBC
A
Storage iron is usually best determined by:
A. Serum transferrin levels
B. Hgb values
C. Myoglobin values
D. Serum ferritin levels
D
All of the following are associated with
sideroblastic anemia except:
A. Increased serum iron
B. Ringed sideroblasts
C. Dimorphic blood picture
D. Increased RBC protoporphyrin
D
What is the basic hematological defect seen in
patients with thalassemia major?
A. DNA synthetic defect
B. Hgb structure
C. β-Chain synthesis
D. Hgb phosphorylation
C
Which of the following is the primary Hgb in
patients with thalassemia major?
A. Hgb D
B. Hgb A
C. Hgb C
D. Hgb F
D
A patient has an Hct of 30%, a hemoglobin of
8 g/dL, and an RBC count of 4.0 × 1012/L. What
is the morphological classification of this anemia?
A. Normocytic normochromic
B. Macrocytic hypochromic
C. Microcytic hypochromic
D. Normocytic hyperchromic
C
In which of the following conditions is Hgb A2
elevated?
A. Hgb H
B. Hgb SC disease
C. β-Thalassemia minor
D. Hgb S trait
C
In which of the following conditions is Hgb A2
elevated?
A. Hgb H
B. Hgb SC disease
C. β-Thalassemia minor
D. Hgb S trait
C
. Which of the following parameters may be similar
for the anemia of inflammation and iron deficiency
anemia?
A. Normocytic indices
B. Decreased serum iron concentration
C. Ringed sideroblasts
D. Pappenheimer bodies
B
