Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

HEMATOLOGY (HARR) > Basic concepts and laboratory procedure > Flashcards

Basic concepts and laboratory procedure Flashcards

1
Q

Insufficient centrifugation will result in:
A. A false increase in hematocrit (Hct) value
B. A false decrease in Hct value
C. No effect on Hct value
D. All of these options, depending on the patient

A

A. Insufficient centrifugation does not pack down the red blood cells; therefore, the Hct, which is the
volume of packed cells, will increase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Variation in red cell size observed on the
peripheral smear is described as:
A. Anisocytosis
B. Hypochromia
C. Poikilocytosis
D. Pleocytosis

A

A. A mature erythrocyte is approximately 7–8 μm in
diameter. Variation in normal size is denoted by the
term anisocytosis. Hypochromia is a term that
indicates increased central pallor in erythrocytes, and poikilocytosis denotes variation in red cell shape.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Which of the following is the preferable site for
bone marrow aspiration and biopsy in an adult?
A. Iliac crest
B. Sternum
C. Tibia
D. Spinous processes of a vertebra

A

A. The iliac crest is the most frequently used site for
bone marrow aspiration and biopsy. This site is the
safest and most easily accessible, with the bone just beneath the skin, and neither blood vessels nor
nerves are in the vicinity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Mean cell volume (MCV) is calculated using the
following formula:
A. (Hgb ÷ RBC) × 10
B. (Hct ÷ RBC) × 10
C. (Hct ÷ Hgb) × 100
D. (Hgb ÷ RBC) × 100

A

B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What term describes the change in shape of
erythrocytes seen on a Wright’s-stained peripheral
blood smear?
A. Poikilocytosis
B. Anisocytosis
C. Hypochromia
D. Polychromasia

A

A. Variation in shape of the erythrocytes on a peripheral blood smear is poikilocytosis. Anisocytosis refers to a change in size. Hypochromia is an increase in central pallor in erythrocytes. Polychromasia describes the bluish tinge of the immature erythrocytes (reticulocytes) circulating in the peripheral blood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

When an erythrocyte containing iron granules is
stained with Prussian blue, the cell is called a:
A. Spherocyte
B. Leptocyte
C. Schistocyte
D. Siderocyte

A

D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

A 7.0-mL ethylenediaminetetraacetic acid (EDTA)
tube is received in the laboratory containing only
2.0 mL of blood. If the laboratory is using manual
techniques, which of the following tests will most
likely be erroneous?
A. RBC count
B. Hemoglobin (Hgb)
C. Hct
D. WBC count

A

C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

A decreased osmotic fragility test would be
associated with which of the following conditions?
A. Sickle cell anemia
B. Hereditary spherocytosis
C. Hemolytic disease of the newborn
D. Acquired hemolytic anemia

A

A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What effect would using a buffer at pH 6.0 have
on a Wright’s-stained smear?
A. Red cells would be stained too pink
B. White cell cytoplasm would be stained too blue
C. Red cells would be stained too blue
D. Red cells would lyse on the slide

A

A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which of the following erythrocyte inclusions can
be visualized with supravital stain but cannot be
detected on a Wright’s-stained blood smear?
A. Basophilic stippling
B. Heinz bodies
C. Howell–Jolly bodies

A

B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

A falsely elevated Hct is obtained. Which of the
following calculated values will not be affected?
A. MCV
B. MCH
C. MCHC
D. Red cell distribution width (RDW)

A

B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

A Miller disk is an ocular device used to facilitate
counting of:
A. Platelets
B. Reticulocytes
C. Sickle cells
D. Nucleated red blood cells (NRBCs)

A

B

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

SITUATION: RBC indices obtained on an anemic
patient are as follows: MCV 88 μm3 (fL); MCH
30 pg; MCHC 34% (.340). The RBCs on the
peripheral smear would appear:
A. Microcytic, hypochromic
B. Microcytic, normochromic
C. Normocytic, normochromic
D. Normocytic, hypochromic

A

C

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

All of the following factors may influence the
erythrocyte sedimentation rate (ESR) except:
A. Blood drawn into a sodium citrate tube
B. Anisocytosis, poikilocytosis
C. Plasma proteins
D. Caliber of the tube

A

A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

All of the following factors may influence the
erythrocyte sedimentation rate (ESR) except:
A. Blood drawn into a sodium citrate tube
B. Anisocytosis, poikilocytosis
C. Plasma proteins
D. Caliber of the tube

A

A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

All of the following factors may influence the
erythrocyte sedimentation rate (ESR) except:
A. Blood drawn into a sodium citrate tube
B. Anisocytosis, poikilocytosis
C. Plasma proteins
D. Caliber of the tube

A

B

17
Q

The Coulter principle for counting of cells is based
upon the fact that:
A. Isotonic solutions conduct electricity better than
cells do
B. Conductivity varies proportionally to the number
of cells
C. Cells conduct electricity better than saline does
D. Isotonic solutions cannot conduct electricity

A

A

17
Q

The Coulter principle for counting of cells is based
upon the fact that:
A. Isotonic solutions conduct electricity better than
cells do
B. Conductivity varies proportionally to the number
of cells
C. Cells conduct electricity better than saline does
D. Isotonic solutions cannot conduct electricity

A

A

18
Q

A correction is necessary for WBC counts when
nucleated RBCs are seen on the peripheral smear
because:
A. The WBC count would be falsely lower
B. The RBC count is too low
C. Nucleated RBCs are counted as leukocytes
D. Nucleated RBCs are confused with giant
platelets

A

B

19
Q

Given the following values, which set of red blood
cell indices suggests spherocytosis?
A. MCV 76 μm3 MCH 19.9 pg MCHC 28.5%
B. MCV 90 μm3 MCH 30.5 pg MCHC 32.5%
C. MCV 80 μm3 MCH 36.5 pg MCHC 39.0%
D. MCV 81 μm3 MCH 29.0 pg MCHC 34.8%

A

C Spherocytes have a decreased cell diameter and
volume, which results in loss of central pallor and
discoid shape. The index most affected is the MCHC, usually being in excess of 36%

20
Q

Which of the following statistical terms reflects
the best index of precision when comparing two
CBC parameters?
A. Mean
B. Median
C. Coefficient of variation
D. Standard deviation

A

C

21
Q

Which of the following is considered a normal
hemoglobin?
A. Carboxyhemoglobin
B. Methemoglobin
C. Sulfhemoglobin
D. Deoxyhemoglobin

A

D

22
Q

Which condition will shift the oxyhemoglobin
dissociation curve to the right?
A. Acidosis
B. Alkalosis
C. Multiple blood transfusions
D. Increased quantities of hemoglobin S or C

A

A

23
Q

Which condition will shift the oxyhemoglobin
dissociation curve to the right?
A. Acidosis
B. Alkalosis
C. Multiple blood transfusions
D. Increased quantities of hemoglobin S or C

A

A

24
Q

What is the major type of leukocyte seen in
the peripheral smear of a patient with aplastic
anemia?
A. Segmented neutrophil
B. Lymphocyte
C. Monocyte
D. Eosinophil

A
25
Q

What is the major type of leukocyte seen in
the peripheral smear of a patient with aplastic
anemia?
A. Segmented neutrophil
B. Lymphocyte
C. Monocyte
D. Eosinophil

A

B

26
Q

What is the major type of leukocyte seen in
the peripheral smear of a patient with aplastic
anemia?
A. Segmented neutrophil
B. Lymphocyte
C. Monocyte
D. Eosinophil

A

B

27
Q

What is the normal WBC differential lymphocyte
percentage (range) in the adult population?
A. 5%–10%
B. 10%–20%
C. 20%–44%
D. 50%–70%

A

C

28
Q

In which age group would 60% lymphocytes be a
normal finding?
A. 6 months–2 years
B. 4–6 years
C. 11–15 years
D. 40–60 years

A

A

29
Q

Which of the following results on an automated
differential suggests that a peripheral smear should
be reviewed manually?
A. Segs = 70%
B. Band = 6%
C. Mono = 15%
D. Eos = 2%

A

C

30
Q

Which is the first stage of erythrocytic maturation
in which the cytoplasm is pink due to the
formation of hemoglobin?
A. Reticulocyte
B. Pronormoblast
C. Basophilic normoblast
D. Polychromatic normoblast

A

D

31
Q

Which of the following can shift the hemoglobin
oxygen dissociation curve to the right?
A. Increases in 2,3 DPG
B. Acidosis
C. Hypoxia
D. All of these options

A

D

32
Q

Which of the following Hgb configurations is
characteristic of Hgb H?
A. γ4
B. α2-γ2
C. β4
D. α2-β2

A

C

33
Q

Autoagglutination of red cells at room temperature
can cause which of the following abnormal test
results?
A. Low RBC count
B. High MCV
C. Low hematocrit
D. All of these options

A

D

HEMATOLOGY (HARR) (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions