Macrocytic and normochromic anemias Flashcards
Which morphological classification is
characteristic of megaloblastic anemia?
A. Normocytic, normochromic
B. Microcytic, normochromic
C. Macrocytic, hypochromic
D. Macrocytic, normochromic
D
Which anemia is characterized by a lack of
intrinsic factor that prevents B12 absorption?
A. Tropical sprue
B. Transcobalamin deficiency
C. Blind loop syndrome
D. Pernicious anemia
D
All of the following are characteristics of
megaloblastic anemia except:
A. Pancytopenia
B. Elevated reticulocyte count
C. Hypersegmented neutrophils
D. Macrocytic erythrocyte indices
B
A patient with a vitamin B12 anemia is given a
high dosage of folate. Which of the following is
expected as a result of this treatment?
A. An improvement in neurological problems
B. An improvement in hematological abnormalities
C. No expected improvement
D. Toxicity of the liver and kidneys
B
Which of the following disorders is associated with
ineffective erythropoiesis?
A. G6PD deficiency
B. Liver disease
C. Hgb C disease
D. Megaloblastic anemia
D
A 50-year-old patient is suffering from pernicious
anemia. Which of the following laboratory data
are most likely for this patient?
A. RBC = 2.5 × 1012/L; WBC =12,500/μL (12.5 ×
109/L); PLT = 250,000/μL (250 × 109/L)
B. RBC = 4.5 × 1012/L; WBC = 6,500/μL (6.5 ×
109/L); PLT = 150,000/μL (150 × 109/L)
C. RBC = 3.0 × 1012/L; WBC = 5,000/μL (5.0 ×
109/L); PLT = 750,000/μL (750 × 109/L)
D. RBC = 2.5 × 1012/L; WBC = 2,500/μL (2.5 ×
109/L); PLT = 50,000/μL (50 × 109/L)
D
Which of the following may be seen in the
peripheral blood smear of a patient with
obstructive liver disease?
A. Schistocytes
B. Macrocytes
C. Howell–Jolly bodies
D. Microcytes
B
The macrocytes typically seen in megaloblastic
processes are:
A. Crescent-shaped
B. Teardrop-shaped
C. Ovalocytic
D. Pencil-shaped
C
. Which of the following are most characteristic of
the red cell indices associated with megaloblastic
anemias?
A. MCV 99 fl, MCH 28 pg, MCHC 31%
B. MCV 62 fL, MCH 27 pg, MCHC 30%
C. MCV 125 fL, MCH 36 pg, MCHC 34%
D. MCV 78 fL, MCH 23 pg, MCHC 30%
C
A patient has 80 nucleated red blood cells per 100
leukocytes. In addition to increased polychromasia
on the peripheral smear, what other finding may
be present on the CBC?
A. Increased platelets
B. Increased MCV
C. Increased Hct
D. Increased red blood cell count
B
