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QUESMED LEARNING > QQ > Flashcards

QQ Flashcards

1
Q

Antibiotic that reacts dangerously with methotrexate

A

Trimethoprim

Potentiates folate inhibition

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2
Q

Electrolyte disturbances in Addison’s disease

A

Hyponatraemia
Hyperkalaemia

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3
Q

Initial treatment of Raynaud’s disease (beyond gloves)

A

Calcium channel blockers e.g. Nifedipine

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4
Q

Surgical technique to remove basal cell carcinoma in cosmetically sensitive areas

A

Mohs micrographic surgery

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5
Q

Positive light bulb sign

A

Posterior dislocation of shoulder

(can be caused by electrocution)

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6
Q

Systemic sclerosis antibody

A

Scl-70 (Anti-toiposomerase 1)
Anti-centromere
Anti-RNA polymerase III

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7
Q

Rheumatoid arthritis affects which hand joints?

A

PIPs and MCPs

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8
Q

Bilateral proximal muscle pain in older patients + sometimes low grade fever, no rise in CK levels

A

Polymyalgia rheumatica

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9
Q

Screening test for primary hyperaldosteronism

A

Aldosterone:renin ratio

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10
Q

Low gonadotrophins (LH and FSH) resulting in low testosterone production (can cause gynaecomastia)

A

Hypogonadotrophic hypogonadism

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11
Q

MOA of carbimazole

A

Inhibits iodine and TPO

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12
Q

Pathogen that causes acne

A

Propionobacterium acnes

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13
Q

Most common cause of hypothyroidism worldwide

A

Iodine deficiency

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14
Q

CREST syndrome a.k.a. ________

A

LImited cutaneous systemic sclerosis

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15
Q

CREST syndrome stands for…

A

Calcinosis
Raynaud’s phenomenon
oEsophageal dysmotility
Sclerodactyly
Telangectasia

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16
Q

Methotrexate + increasing tiredness =

A

Folic acid deficiency

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17
Q

Cranial DI water deprivation test results:

A

Low after water deprivation, normal after desmopressin

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18
Q

Nephrogenic DI water deprivation test results:

A

Low after water deprivation, low after desmopressin

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19
Q

Finklestein’s test tests for ________

A

De Quervain’s tenosynovitis

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20
Q

Condition that often presents with Giant cell arteritis

A

Polymyalgia rheumatica

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21
Q

Waterhouse-Friedrichsen syndrome most common cause

A

Meningitis

Also associated with other bacterial pathogens and splenectomy

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22
Q

Medication contraindicated with methotrexate

A

Trimethoprim

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23
Q

Commonest cause of anovulation in women?

A

Polycystic ovarian syndrome (PCOS)

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24
Q

Definitive test for Giant Cell Arteritis

A

Temporal artery biopsy

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25
Q

Cause of foot drop

A

Damage to common peroneal nerve

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26
Q

Treatment for poly/dermatomyositis

A

High dose corticosteroids which are then tapered down according to CK levels

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27
Q

Clinical test for axillary nerve damage

A

Test sensation over lower half of deltoid muscle

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28
Q

Lichen planus 6 Ps

A

Purple
Pruritic (itchy)
Polygonal (multiple sides)
Planar (flat-topped)
Papules or
Plaques

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29
Q

Tests to monitor methotrexate toxicity

A

LFTs, renal function, FBC, chest X-ray (to check for pneumonitis)

30
Q

Bedside test needed for patients with SLE

A

Urine dipstick to check for lupus glomerulonephritis

31
Q

Tennis elbow =

A

Lateral epicondylitis

32
Q

Golfer’s elbow =

A

Medial epicondylitis

33
Q

Initial management of DKA

A

IV 0.9% sodium chloride (saline)

34
Q

MOA of alendronate (a bisphosphonate)

A

Inhibits osteoclasts

(responsible for bone resorption)

35
Q

Positive lupus anticoagulant assay =

A

Antiphospholipid syndrome

(can occur secondary to SLE)

36
Q

Antiphospholipid syndrome - which drug should be avoided?

A

Combined oral contraceptive pill (COCP)

37
Q

Swan neck and Boutonniere’s deformities

A

Rheumatoid arthritis

38
Q

Ophthalmic complication of Giant Cell Arteritis

A

Anterior ischaemic optic neuropathy

39
Q

Patients on long-term steroids can develop a ‘cushingoid’ appearance, with features such as…

A

Moon face, buffalo hump, central obesity

40
Q

Antiphospholipid syndrome autoantibodies (3 of them)

A

Anti-cardiolipin
Anti-beta2-GPI
Positive lupus anticoagulant assay

41
Q

Fractures of the humeral shaft damage which nerve?

A

Radial nerve

42
Q

Contraindication for alendronic acid

A

Oesophageal stricture

43
Q

What test needs to be done at baseline as part of the monitoring protocol for Hydroxychloroquine?

A

Eye assessment

(due to risk of hydroxychloroquine-induced retinopathy

44
Q

Bilateral phaeochromocytomas can be caused by which condition?

A

MEN 2B

45
Q

Why does an urticarial rash occur?

A

After an allergic reaction

46
Q

Common rash which often occurs after an upper respiratory tract infection

A

Pityriasis rosea

47
Q

Wickham’s striae (lacy white lines) on mucosal surfaces

A

Lichen planus

(6 Ps
Purple, Pruritic, Papular, Polygonal, Planar)

48
Q

Which anti-hyperglycaemic drug is most likely to cause a hypoglycaemic event?

A

Sulphonylureas
(e.g. gliclazide)

49
Q

Notable feature of De Quervain’s

A

Painful thyroid

50
Q

Before starting biologics, what condition must be screened for?

A

TB

51
Q

1st and 2nd line eczema treatment

A
  1. Topical emollient
  2. Topical corticosteroid
52
Q

Reactive overgrowth of capillaries due to minor trauma to fingers. A benign lesion.

A

Pyogenic granuloma

53
Q

Abdominal pain + dermatitis herpetiformis (itchy, blistering rash)

A

Coeliac disease

54
Q

Dermatomyositis antibodies

A

Anti-Jo1

55
Q

Iamotrigine (epilepsy drug) major side effect

A

Stevens-Johnson Syndrome

Presents with systemic upset, mucocutaneous ulceration with skin sloughing.
Occurs within 8 weeks drug initiation.

56
Q

Itchy, red rash with pustules within his pubic hair. STD

A

Folliculitis

57
Q

Diagnostic test for dermatomyositis

A

Muscle biopsy

58
Q

What is Koebner’s phenomenon?

A

Formation of a skin lesion at a previous injury site

59
Q

What is Russell’s sign?

A

Scarring of the knuckles.
Suggests bulimia

60
Q

What is Leser-Trelat sign?

A

Sudden rapid increase in seborrheoic keratoses

Commonly caused by malignancy
such as gastric adenocarcinoma

61
Q

First line treatment for seborrheoic keratosis

A

Removal by cryotherapy, excision, curettage or laser ablation

62
Q

Staphylococcal Scalded Skin Syndrome affects the oral mucosa. T/F?

A

False.
Toxic Epidermal Necrolysis does.

63
Q

First line treatment for SSSS

A

IV flucloxacillin + topical fusidic acid (to target the underlying staph. infection)

64
Q

Treatment for scabies

A

Topical permethrin

65
Q

Skin complication of sarcoidosis

A

Erythema nodosum

66
Q

Molluscum contagiosum treatment

A

Watch and wait
(self resolves after 3 months)

If removing for cosmetic reasons, perform cryotherapy

67
Q

Penicillin use + acute skin problems + mouth involvement

A

Toxic Epidermal Necrolysis

68
Q

Strep. throat leads to what skin condition?

A

Guttate psoriasis

69
Q

Viral infection can lead to what skin condition?

A

Pityriasis rosea

70
Q

Dermatophyte fungal skin infections can trigger what skin condition?

A

Pityriasis versicolor

71
Q

Treatment for keloid scarring

A

Intralesional steroids

72
Q

Treatment for lichen planus

A

Potent topical steroids e.g. betamethasone

QUESMED LEARNING (18 decks)

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