LESGOO

Question 1

Giant cell arteritis =

Answer 1

Temporal arteritis

Temporal arteries inflamed > unable to brush hair as scalp is so sensitive, vision in one eye is blurred

Question 2

Tests for Sjögren’s syndrome (including antibodies)

Answer 2

Schirmer’s test - ocular dryness (tears)

Bloods: Anti-Ro and Anti-La

Lymphocytic infiltrates on a lip gland biopsy

Question 3

SLE symptoms

Answer 3

General: Fever, fatigue, weight loss

Cutaneous: Malar rash, alopecia, oral/nasal ulcers, Raynaud’s, Discoid lupus erythematosus

MSK: Arthritis, arthralgia, myalgia, Jaccoud’s arthropathy

Renal - lupus nephritis
Neurological - seizures, delirium, psychosis, headache, cranial nerve disorder
Serositis - pleural/pericardial effusion, acute pericarditis
Haematological - leukaemia, thrombocytopenia, hemolytic anaemia, lymphadenopathy

Question 4

Anterior knee pain at the inferior pile of the patella - chronic

Answer 4

Patellar tendinitis / Jumper’s knee

Exacerbated by exercise - moderate pain present all the time

Question 5

Rheumatoid arthritis, splenomegaly, neutropenia

Answer 5

Felty’s syndrome triad

Question 6

Paediatric fracture where the cortex surface breaks but the bone itself doesn’t

Answer 6

Greenstick fracture

Question 7

What does CREST syndrome stand for?

Answer 7

Calcinosis
Raynaud’s phenomenon
Esophageal dysmotility
Sclerodactyly
Telangectasia

Question 8

Test for giant cell arteritis

Answer 8

ESR
(often levels greater than 50mm/hr)

Question 9

Most concerning side effect of Carbimazole

Answer 9

Sore throat
(Also fever and throat/mouth ulcers)
Shows bone marrow suppression which could lead to agranulocytosis which could then lead to life-threatening sepsis

Question 10

Granulomatosis with polyangiitis triad

Answer 10

Upper respiratory tract involvement
Lower respiratory tract involvement
Renal involvement

Question 11

What class of drug are -gliflozins?

Answer 11

SGLT2 inhibitors

Question 12

Antiphospholipid antibodies:
(3 of them)

Answer 12

Anticardiolipin
Anti-B2 glycoprotein I
Lupus anticoagulant

Question 13

Acromegaly common features

Answer 13

Coarse facial features, oily skin, carpal tunnel syndrome, joint pain, snoring, erectile problems, irregular periods, large hands and feet, abnormally tall

Question 14

SIADH symptoms

Answer 14

Hyponatraemia, water retention, low mood, nausea, vomiting, cramps, tremors

Question 15

Garden classification is used for ?

Answer 15

Intra-capsular fractures of the femoral neck

(Grades 3 and 4 require open surgery)

Question 16

First line for mild acne vulgaris

Answer 16

Topical benzoyl peroxide + adapalene

Question 17

Graves disease patient. What in the main risk factor for thyroid eye disease?

Answer 17

Smoking !

Question 18

Drugs that can cause medication-induced diabetes

Answer 18

Steroids
Atypical neuroleptics
Thiazides
Beta-blockers

Question 19

Dermatomyositis presentation

Answer 19

Heliotrope rash
Gottron’s papules
Macular erythematous rash on head, neck, trunk, hands
Periungual erythema

(Can be a paraneoplastic phenomenon)

Question 20

First line management of Type 1 diabetes

Answer 20

Basal-bolus insulin

Question 21

Results to diagnose impaired fasting glucose:

Answer 21

Fasting glucose 6.8mmol/L on two occasions

Question 22

Treatment for acute flame of rheumatoid arthritis

Answer 22

Intramuscular steroids e.g. methylprednisolone

Question 23

T2DM + Cardiovascular disease
What class of drug should be added?

Answer 23

SGLT2 inhibitors
e.g. Empagliflozin

Question 24

Fat embolism main risk factor

Answer 24

Long bone fracture e.g. femur

Question 25

Garden classification is used to grade what type of fractures?

Answer 25

Intra-capsular fractures of the femoral neck