HWFGA

Question 1

Polymyositis + dermatomyositis.
What blood tests are significantly raised?

Answer 1

Creatine kinase
(can be up to 50x the normal amount)

Question 2

Antibodies present in Graves’ disease ?

Answer 2

TSH-receptor antibodies

Question 3

MOA of Alendronate (for osteoporosis)

Answer 3

Inhibits osteoclasts

Question 4

Most common mechanism of visual loss in Giant Cell arteritis =

Answer 4

Anterior ischaemic optic neuropathy

causes a swollen, chalky-white optic disc

Question 5

Winged scapula caused by which nerve?

Answer 5

Long thoracic nerve

Question 6

Typical cause of a fat embolism

Answer 6

Fracture of long bone e.g. femur

Question 7

SLE: What autoantibody is most likely to be present?

Answer 7

ANA

Question 8

Most specific antibodies (2) for rheumatoid arthritis

Answer 8

Anti-CCP (95%)
Rheumatoid Factor (85%)

Question 9

Ongoing rheumatoid arthritis despite combination DMARD therapy. What medication?

Answer 9

Anti-TNFa ‘biologic’ therapy

Question 10

Ophthalmic complication of ankylosing spondylitis

Answer 10

Anterior uveitis

Question 11

Test for refractive error

Answer 11

Pinhole-aided visual acuity

Question 12

Corneal graft rejection symptoms

Answer 12

Oedema, iritis, redness, pain and visual loss following corneal graft