Purpura Flashcards

1
Q

Quels sont les signes de gravités du purpura thrombopenique?

A
Extensif
Necrotique
Thrompenie<20 000
Hemorr spontané
Bulles hemorr endobuccales
Hemorr digestive
Hemorr retine : FO+++
Hemo cerebro meningé ( cephalee, sd meningée, conscience)
T°C
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2
Q

Faire dg biologique de CIVD

A
Nfs
Plaquettes
Tq
Fibrinogene
Pdf dd
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3
Q

Quels sont les 3 sortes de pirpura et leurs caracteristiques

A

1/ THROMBOPENIQUE
patechial, ecchymotique, non infiltre, diffus, atteinte muqueses, hemorr visceres, gingivorragie buccale

2/VASCULAIRE
infiltré et necrotique, predominance MI, declive, pas miquese

3/PURPURA THROMBOTIQUE
Infiltre, et necrotique et liseré purpurique autour

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4
Q

Etiologies des purpura thromboembolique

A
CIVD
Necrose induite par haparine ac apf4
Diminution prt C et S post AVK
SAPL : livedo
Cryoglobu
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5
Q

Etiologie purpura vasculaires

A
1/ vascularite
Pan
Anca
Cic : cryo, medocs, purpura rhum
Connectivites : les. Gj, cryo, sapl
2/ INFECTIEUX
virales : vhb, vhc, ebv, cmv, vih, pb19
Endocardite : purpura ss clav et conjonctival,bact. Ricckettiose :
Paludisme
Fulminans
3/ fragilité capillaire
Alylose
P senile batman
Cortico
Diabete
Ehlers danlos
Xanthome elastique
Idiopathique femme jeune
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6
Q

Purpura thrombopathique

A
Iatrogene ; aspirine, aap, ains, isrs, penivilline
WB
myelome, waldenstrom
Cirrhose et IHC
IRC
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7
Q

Thrombopenie etio

A

P581

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8
Q

Bilan purpura 1 er

Et bilan purpura vascu

A

P581

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9
Q

Quand faire myelogramme devant thrombopenie isole

A

> 60 ans
Autres ligné cytopenie
Adenomegalie adp, hsmg

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10
Q

Bilan devant throbopenie isole

A

1/ refaire prelevement sur tube CITRATÉ

Frottis sg: schyzo, aggregation plq. Lymphoc atypiq
Fibrinegene
Vih vhb vhc
Eps
Bhc
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11
Q

Bilan face a PTI

A
Dg d'elimination
Donc eliminer
Serolgies virales vhc vhb vih ebv
Coolbs-
Bilan immuno : aan, cmpt, tsh, 
Test urease : helPilory
Tp. Tca, fibrinogene
Gp et rh et rai

FO: hemorragie?
Si s meningé : tdm c

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12
Q

Quand ttt pti

A

Abstention si plq>30 et pas de signes de gravite

Ttt si buchana >3 : atteinte miqueuse saignement: epistaxis, bulles endobuccal et si
Corticottt ou et immgIv

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