purinas y pirimidinas Flashcards

1
Q

Cuáles son las purinas?

A

Adenina
Guanina

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2
Q

Sustrato de síntesis de purinas

A

ribosa 5 fosfato

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3
Q

Producto de síntesis de purinas

A

ATP y GTP

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4
Q

Enzimas de regulación alostérica de síntesis de purinas

A

ribosa-P pirofosfatocinasa
adenilosuccinatosintetasa

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5
Q

Mineral importante para el ATP

A

Mg

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6
Q

Enzimas que unen bases nitrogenadas con PRPP

A

adeninafosforribociltransferasa-AMP
hipoxantinaguaninafosforibociltransferasa-GMP y IMP

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7
Q

bases nitrogenadas que se pueden unir a un PRPP

A

Adenina–AMP
Guanina–GMP
Hipoxantina–IMP

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8
Q

Enfermedad cuando hay acumulación de ácido úrico (hiperuricemia)

A

Gota

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9
Q

Qué síndrome da cuando no hay hipoxantinaguaninafosforribociltransferasa

A

Sx de Lesch Nyhan

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10
Q

Cuántos ATPs se necesitan para la síntesis de Purinas

A

5

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11
Q

Qué moléculas se ocupan en la síntesis de purinas

A

5 ATPS
2 Glutaminas
2 folatos
1 glicina
1 CO2
1 aspartato

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12
Q

Molécula precursora de nucleótidos

A

IMP

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13
Q

Sustrato de la degradación de GMP

A

GMP

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14
Q

Producto de la degradación de purinas

A

1 base nitrogenada+ribosa+fósforo
o ácido úrico

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15
Q

Cuáles son las pirimidinas?

A

citosina
uracilo
timina

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16
Q

Qué diferencia a las purinas de las pirimidinas

A

las purinas tienen dos anillos y las pirimidinas solo uno

17
Q
A