Gluconeogénesis Flashcards

1
Q

en qué parte de la célula ocurre la gluconeogénesis?

A

citoplasma de hígados y riñones

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2
Q

Sustrato

A

Piruvato(2 moléculas)
junto con lactato y alanina y glicerol

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3
Q

Producto

A

Glucosa

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4
Q

vía metabólica necesaria para la gluconeogénesis?

A

Ciclo de Cori

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5
Q

Qué hace el Ciclo de Cori?

A

transporta el lactato del músculo al hígado

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6
Q

enzimas !!!

A

piruvato carboxilasa(mitocondria)
PEP carboxiquinasa(citoplasma)
fructosa 1,6 bifosfatasa
glucosa6fosfatasa

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7
Q

El GTP del 1er paso de la gluconeogénesis viene de qué VM?

A

Del Ciclo de Krebs
De este GTP viene el fosfato

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8
Q

1er paso gluconeogénesis

A

piruvato carboxilasa pasa a oxaloacetato y luego a PEP carboxiquinasa
sacando 2 ADP y 2 GTP

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9
Q

2da fase

A

fructosa 1,6 bifosfatasa
quita P

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10
Q

3era fase

A

glucosa6fosfatasa

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11
Q

Si el AcetilCoA sube…

A

se activa la gluconeogénesis

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12
Q

Si sube la insulina…

A

se inhibe la gluconeogénesis

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13
Q

Si sube el glucagon

A

se activa gluconeogénesis

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14
Q

Si se activa el AMPcíclico…

A

se inhibe la gluconeogénesis

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15
Q

Si sube Glu6fosfato…

A

se activa gluconeogénesis

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