Pulmonology Flashcards
path in asthma
reversible inflammation and bronchoconstriction
pt in asthma
SOB, wheezing, hyper resonant, prolonged expiration, exposure to trigger (cold air, allergens)
CBC = eosinophilia; ‘nasal polyps’
dx of asthma
PFTs - FEV1/FVC decreased - reversible with bronchodilators - inducible with methacholine skin test = identify triggers
tx of asthma
ß-agonists - short-acting, long-acting steroids - inhaled corticosteroids, oral prednisone stabilizers - nedocromil, cromolyn - leukotriene antagonists
f/u asthma
avoid triggers
chronic asthma treatment I
SABA
chronic asthma treatment II
SABA + ICS (LTA = ICS)
chronic asthma treatment III
SABA + ICS + LABA
chronic asthma treatment IV
SABA + increase ICS + LABA
refractory asthma treatment
oral prednisone
asthma drugs - SABA
albuterol
asthma drugs - LABA
formoterol, salmetrol
asthma drugs - ICS
beclomethasone, budesonide, fluticasone, mometasone
asthma drugs - steroids
prednisone (oral)
asthma exacerbation path
exposure to trigger
asthma exacerbation pt
exposure to trigger = wheezing, dyspnea, prolonged exhalation
CBC = eosinophilia
nasal polyps
asthma exacerbation dx
clinical
peak flow
asthma exacerbation tx
IV methylprednisolone
albuterol + ipratroprium
steroid taper
asthma exacerbation f/u
racemic epinephrine
magnesium
stops wheezing or CO2 rising -> intubate
lung cancer path
smoking, toxic exposure
lung cancer pt
weight loss, hemoptysis, dyspnea, pleural effusion (tap effusion first)
lung cancer dx
1st: cxr
then: CT
best: biopsy
- percutaneous if peripheral
- endoscopic ultrasound if proximal
- VATS if in the middle
- lobectomy okay too
lung cancer tx
diagnose, stage
PFTs (can they tolerate surgerY?)
surgery vs. chemo
lung cancer f/u
annual low-dose CT scan…cancer screen
- smoker within 15yrs
- 55-80y/o
- > 30 pack-year history
small cell lung cancer path
smoking
small cell lung cancer pt
sentral mass (central) paraneoplastic syndromes - SIADH = HypoNa - ACTH = Cushing's
small cell lung cancer dx
bronch/EUS
small cell lung cancer tx
chemo
squamous cell lung cancer path
smoking
squamous cell lung cancer pt
sentral mass (central) paraneoplastic syndromes - PTH-rp = HyperCa
squamous cell lung cancer dx
bronch/EUS
squamous cell lung cancer tx
resection
chemo, radiation
adenocarcinoma path
asbestosis
cancer NON smokers get
adenocarcinoma pt
peripheral mass
pleural plaques
adenocarcinoma dx
percutaneous biopsy
adenocarcinoma tx
chemo/rads
carcinoid tumor path
serotonin
carcinoid tumor pt
wheezing, flushing, diarrhea
carcinoid tumor dx
5-HIAA in the urine
carcinoid tumor tx
resection
pleural effusion path
transudate: ‘fluid’
- increase hydrostatic = CHF
- decrease oncotic = cirrhosis, nephrosis
exudative: ‘stuff’
- increase permeability = TB, cancer, PNA
pleural effusion pt
exertional dyspnea, orthopnea,
incidentally found on xray
pleural effusion dx
1st: cxr
then: decubitus cxr (or ultrasound)
then: thoracentesis (not loculated)
OR
thoracotomy (loculated)
OR
thoracotomy (empyema)
Best: biopsy, gram stain, cytology
pleural effusion tx
if CHF, do NOT tap, just diuresis
if no CHF, tap, then treat accordingly to the underlying diagnosis
thoracentesis
needle in the chest
thoracostomy
chest tube in chest