Pediatrics Flashcards
APGAR criteria
appearance pulse grimace activity respiration
APGAR: appearance
0 = blue/pale 1 = acrocyanosis 2 = pink
APGAR: pulse
0 = absent 1 = <100 2 = >100
APGAR: grimace
0 = absent 1 = lots of stim 2 = with stim
APGAR: activity
0 = absent 1 = flexion 2 = resist extension
APGAR: respiration
0 = absent 1 = irregular 2 = strong
primary neonatal apnea path
understimulation
C-section
primary neonatal apnea pt
no respirations from the start
primary neonatal apnea dx
clinical
primary neonatal apnea tx
stimulate baby
suction
secondary neonatal apnea path
uncertain
secondary neonatal apnea pt
baby was breathing then stops
secondary neonatal apnea dx
ensure patent airway
secondary neonatal apnea tx
PPV
neonatal dyspnea causes
TTN
RDS
TTN path
self-limiting
C-sections
TTN pt
near-term
grunting
TTN dx
hyperextended
wet
TTN tx
PPV
RDS path
developmental
deficient surfactant
RDS pt
premature
perinatal distress
RDS dx
hypoextended
atelectasis
RDS tx
intubation and surfactant
newborn hypoglycemia path
risk factors
- LGA, infant DM mother
- small gestational age, IUGR
newborn hypoglycemia pt
jitteriness, tremors, lethargy, poor feeding
newborn hypoglycemia dx
every babe gets a glucose check
newborn hypoglycemia tx
if sx = IV glucose
if asx = feed
newborn hypoglycemia f/u
sepsis
bronchopulmonary dysplasia path
decrease surfactant = RDS
prolonged damage = scarring
bronchopulmonary dysplasia pt
increase O2 demands
FiO2 required >28d
lung-protective strats
bronchopulmonary dysplasia dx
xray = ground-glass opacities
bronchopulmonary dysplasia tx
surfactant (post-birth)
steroids (pre-birth)
bronchopulmonary dysplasia f/u
BPD is to RDS (peds) as DPLD is to ARDS (adult)
retinopathy of prematurity path
neoangiogenesis gone awry
Increase FiO2
retinopathy of prematurity pt
premature infant requiring O2
retinopathy of prematurity dx
eye exam (all premies)
retinopathy of prematurity tx
laser
retinopathy of prematurity f/u
glaucoma
intraventricular hemorrhage (NICU) path
highly vascular ventricles
labile pressures
intraventricular hemorrhage (NICU) pt
premie...asx increase ICP (fontanelles)
intraventricular hemorrhage (NICU) dx
cranial doppler (all premies)
intraventricular hemorrhage (NICU) tx
decrease ICP…shunts, drains
intraventricular hemorrhage (NICU) f/u
intellectual disability, seizures
necrotizing enterocolitis path
dead gut
necrotizing enterocolitis pt
premie…bloody BM
necrotizing enterocolitis dx
xray = pneumatosis intestinalis
necrotizing enterocolitis tx
NPO, IV abx, TPN
necrotizing enterocolitis f/u
surgery
imperforate anus path
VACTERL
imperforate anus pt
no hole on inspection (+/- fistula)
never first temp rectally
imperforate anus dx
visual inspection
cross-table xray
imperforate anus tx
mild = repair now severe = colostomy, repair before toilet training
imperforate anus f/u
Vertebra - u/s sacrum Anus - x-ray Cardiac - echo TE Fistula - x-ray with coiled tube Esophageal atresia - xray with coiled tube Renal - VCUG Limb - xray
meconium ileus path
cystic fibrosis
meconium ileus pt
FTPM and…
no prenatal care (undocumented)
meconium ileus dx
x-ray = dilated loops, gas-filled plug
water-soluble contrast (gastrograffin enema)
meconium ileus tx
water-soluble contrast (gastrografin enema)
meconium ileus f/u
meconium peritonitis = perf
ADEK vitamins
pancreatic enzymes
short stature
hirschsprung’s path
failure of neuron migration = distal colon
absent inhibitor neurons = no relaxation
Hirschsprung’s pt
case 1 (90%): FTPM, explosive stool with DRE case 2 (10%): chronic constipation with overflow incontinence
Hirschsprung’s dx
x-ray: good bowel = dilated; bad bowel = normal
if FTPM: contrast enema
if constipation: anorectal manometry -> increased tone
best = biopsy = absent neurons
Hirschsprung’s tx
surgery
voluntary constipation path
embarrassment or pain
cognitive impairment
voluntary constipation pt
toilet training OR school-aged child
constipation with overflow incontinence
encopresis
voluntary constipation dx
clinical
voluntary constipation tx
bowel regimen (stool softener, motility) disimpaction under anesthesia if necessary
unconjugated bilirubin
lipid soluble
can cross BBB
kernicterus
NO urinary excretion
conjugated bilirubin
water soluble
cannot cross BBB
NO kernicterus
urinary excretion
physiologic jaundice
onset >/= 72h
bilirubin increase <5/d (slow)
D. bili <10% total
resolves in 1wk (term) or 2wks (preterm
pathologic jaundice
onset <24h
bilirubin increase >5/d (fast)
D. bili >10% total
resolves in >/= 1wk (term) or >/= 2wks (preterm)
Crigler-Najjar
NO UDP-glucouronyltransferase
Type 1 die, Type II have unconjugated bili (very rare)
Gilbert’s
decrease UDP-glucuronyltransferase unconjugated bili (mc of these diseases)
Dubin-Johnson
problem with excretion
conjugated hyperbilirubinemia
black liver
Rotor
looks like Dubin-Johnson
conjugated, no black liver
problem with storage
breast-feeding jaundice
< 7d of life
not enough feeding, slowing of gut, increase bili reabsorption
increase feed frequency
breast milk jaundice
> 10d of life
enzyme inhibition by mother’s milk; insufficient conjugation
phototherapy (if needed) and continuation of breast feeding OR supplement with formula x1wk
neonatal jaundice path
unconjugated causes kernicterus
conjugated implies structural lesion
neonatal jaundice pt
baby will be yellow
neonatal jaundice dx
transcutaneous sensor (screen) bilirubin level (diagnostic)
neonatal jaundice tx
if unconjugated: use BLUE LIGHT
if conjugated: evaluate for cause
tracheoesophageal fistula path
+/- fistula
+/- atresia
mc type C (blind pouch of esophagus with fistula from distal esophagus to trachea)
tracheoesophageal fistula pt
nonbiliary emesis day 0
bubbling, gurgling
TE fistula dx
NG tube coils on xray
TE fistula tx
parenteral nutrition
NG tube suction
surgery
pyloric stenosis path
hypertrophy of pylorus
gastric outlet obstruction
pyloric stenosis pt
2-8wks, normal feeds -> projectile
usually a boy
* olive-shaped mass
* visibel peristaltic waves
pyloric stenosis dx
BMP = decrease Cl, decrease K, increase Bicarb u/s = donut sign
pyloric stenosis tx
FIX ELECTROLYTES FIRST = IVF
pyloromyotomy
malrotation path
failure of rotation
malrotation pt
normal uterine course
no polyhydramnios
no down syndrome
malrotation dx
x-ray = double bubble with NORMAL gas pattern beyond
upper GI series
malrotation tx
NGT decompression
surgery
malrotation f/u
volvulus; ischemia
duodenal atresia path
failure to recannulate the duodenum
duodenal atresia pt
+ polyhydramnios
+ down syndrome
duodenal atresia dx
x-ray = double bubble AND no gas beyond
duodenal atresia tx
surgery
annular pancreas path
failure to recannulate the esophagus
annular pancreas pt
+ polyhydramnios
+ Down syndrome
annular pancreas dx
x-ray = double bubble AND no gas beyond
annular pancreas tx
surgery
intestinal atresia path
vascular compromise
intestinal atresia pt
mom = cocaine use
NO down syndrome
intestinal atresia dx
x-ray = double bubble with multiple air-fluid levels
intestinal atresia tx
surgery for baby
confront mom
intestinal atresia f/u
short-gut
congenital diaphragmatic hernia path
bowel in chest
hypoplastic lungs
congenital diaphragmatic hernia pt
scaphoid abdomen
pulmonary distress day 0
bowel sounds in chest
congenital diaphragmatic hernia dx
x-ray (babygram)
congenital diaphragmatic hernia tx
cardiopulmonary stabilization
pulmonary surfactant
surgical repair
gastroschisis path
extrusion of bowel
NO membrane
gastroschisis pt
RIGHT of midline NO membrane (loose bowel)
gastroschisis dx
clinical
gastroschisis tx
silo
gastroschisis f/u
fluid shifts big problem
omphalocele path
extrusion of bowel
intact membrane
omphalocele pt
MIDLINE YES membrane (contained sac)
omphalocele dx
clinical
omphalocele tx
silo
omphalocele f/u
fluid shifts but not as fast
exstrophy of the bladder path
bladder through the skin
exstrophy of the bladder pt
MIDLINE defect
wet with urine
red or shining
no bowel seen
exstrophy of the bladder dx
clinical
exstrophy of the bladder tx
surgically
biliary atresia path
failure of the biliary tree to recanalize
biliary atresia pt
persistent or worsening jaundice at 2kws
direct hyperbili
biliary atresia dx
u/s = absence of ducts
HIDA scan after phenobarb = no contrast in GI
biliary atresia tx
surgical (hepatoportoenterostomy)
biliary atresia f/u
fatal if not corrected
neural tube defects path
genetic syndromes
FOLATE deficiency
failure of the caudal neural tube to fuse
NTDs pt
occulta: tuft of hair only
meningocele: extrusion of meninges without cord
myelomeningocele: extrusion of meninges with cord
NTDs dx
prenatal \+ AFP screen \+ u/s in utero no prenatal care \+ visual inspection
NTDs tx
surgery
NTDs f/u
chiari type II with myelomeningocele
hydrocephalus can lead to learning disabilities
cleft lip/cleft palate path
failure of growth and fusion of the underlying structures
cleft lip/palate pt
spectrum: lip through uvula
spectrum: superficial through transmural
spectrum: unilateral, bilateral, midline
cleft lip/palate dx
clinical
cleft lip/palate tx
surgically
cleft lip/palate f/u
cosmetic deformity
failure to thrive from inability to latch (feed)
developmental milestones: 2 mo
gross motor: lift head
fine motor: tracks past mid
speech: coos
social: social smile
developmental milestones: 4 mo
gross motor: roll over
fine motor: clumsy clap
speech: laughs, squeals
social: looks around
developmental milestones: 6 mo
gross motor: sit up
fine motor: rakes
speech: babbles
social: stranger anxiety
developmental milestones: 1 yr
gross motor: walk
fine motor: pincer grasp
speech: 1-word
social: separation anxiety
developmental milestones: 2 yr
gross motor: steps
fine motor: -
speech: 2-word
social: 2-step commands
developmental milestones: 3 yr
gross motor: trike
fine motor: circle
speech: 3-word
social: -
developmental milestones: 4 yr
gross motor: hop
fine motor: cross
speech: 4-word
social: -
developmental milestones: 5 yr
gross motor: skip
fine motor: triangle
speech: 5-word
social: -
vaccines
MMRV HepA/B DTaP HiB pneumococcal meningococcal HPV flu
FTT
head circumference: last to go
height: lost between
weight: first to go
organic causes of FTT
genetic (CF)
cardiac disease
pyloric stenosis
GERD
non-organic causes of FTT
formula
feeding
frequency
red flags of abuse: injury
suspicious shape
suspicious location
severity
red flags of abuse: child
injured infant
comfort from nurses
comfort from staff
safety to prevent trauma
car seats booster seats seatbelts NO trampolines eliminate guns fence pools
safety for SIDS
sleep on back
don’t share beds
smoking cessation
vaccine contraindications: egg allergy
nothing made with eggs except:
- influenza *US IM flu no longer made with eggs
- yellow fever
vaccine contraindications: immunocompromised or pregnant
no live vaccines
- MMRV
- live attenuated flu (IN)
vaccine contraindications: anaphylaxis
never get that vaccine again
vaccine contraindications: ok to give vaccine again if…
prior local reactions, current illness or fever, family history of ____, autism fear
hep B vaccines
Mom: + Baby: Hep B Ig and Hep B Vax NOW
Mom: - Baby: Hep B within 2 mo
Mom: ? Baby: Hep B NOW, check mom’s HBsAg
DTaP vaccine
kids get 5 doses: - 3 doses in 1st year - 2 doses between 1-4y Td (booster) or Tdap at least once in adolescence and q10y need 3 total doses lifetime
Hib vaccine
disease does not confer immunity in those <2y so give Hib vax
does not cover nontypeable
Hib causes epiglottis and meningitis
MMRV vax
vax and booster before school (1 and 4)
pneumococcal vax
two types: 23 and 13 valent
complete 13 as infant, add 23 if + risk factors
to all immunocompromised and asplenic pt
meningococcal vax
to everyone vs. meningitis…
required for college and military
HPV vax
all boys and girls 9-26
prevents cancer
Hep A/B vax
2 doses for A
3 doses for B
pick up where you left off
Flu vax
everyone. period.
healthcare workers before winter months
given annually
managing a wound with < 3 lifetime DTaP doses (or unknown)
clean: Tdap
Dirty: Tdap + TIG
timing doesn’t matter if <3 lifetime doses
managing a wound with >/= 3 lifetime DTap doses
clean:
- > /= 10y : Tdap
- < 10y : Home
dirty: - > /= 5y : Tdap
- < 5y : home
- NO TIG needed if >/= 3 lifetime doses
pertussis
catarrhal stage (inconspicuous) paroxysmal phase (coughing spells, whoops) resolution phase (regular cold symptoms)
diphtheria
grey pseudomembrane in oropharynx
airway, antibiotics, antitoxin
tetanus
dirty wound, lock jaw, spasms
TIG (block toxin) and toxoid (vaccinate)
lethal dose < immune dose
tube, sedate, MTZ
varicella
no pox parties -> vaccinate instead
kids get MMRV = no chickenpox
adults, no “v” = shingles = varicella @ 60
HPV
boys and girls aged 9-26
does prevent cancer
does not increase sex, STI, pregnancy, etc
rotavirus
oral
contraindicated in intussusception
1st degree burn
epidermis only
+ pain, + erythema
2nd degree burn
epi + dermis
+ pain, + blisters, + erythema
3rd degree burn
through dermis
white and painless with surrounding 2nd deg burns
Parkland formula for burns
%BSA x kg x 4
- 2nd and 3rd degree only
- 50% in 8hrs; 50% in 16hrs
rule of nines for burns
head: 9 + 9 = 18 front thorax: 9 + 9 = 18 back thorax: 9 + 9 = 18 Arms: L = 9; R = 9 = 18 Legs: 9 + 9 + 9 = 27 genitals: 1
epidural hematoma
temple trauma
+ LOC with lucid interval
biconvex ‘lens’
subdural hematoma
major trauma or abuse
+ LOC, no lucidity
concave ‘crescent’
cerebral contusion
major trauma
+ LOC
punctate hemorrhage
head trauma prevention
helmets: in sports and on bikes car safety: - rear facing car seat 0-2y - booster seat until 4'9" and 8-12y/o - seat belts in every car for everyone, every seat eliminate trampolines - nets, soft ground, water don't count
drowning prevention
limit access: locked gates surrounding all pools
supervision: near tubs, pools, and tanks
flotation: use life jackets, NOT arm floaties
up risk: too young to know; too drunk to remember (adolescents)
gun and chemical safety
best: eliminate them from the home
OK: keep them out of reach - store up high; keep them locked in a safe or locked cabinet, do not depend on ‘child proof’ lids
guns: ammo stored separately from weapon; store guns unloaded
severity of concussion to treatment: mild:
FND: none LOC: <60sec HA: none, improving amnesia: none No CT d/c home
severity of concussion to treatment: severe
FND: positive LOC: >60sec HA: persistent or worsening amnesia: retrograde or anterograde CT scan observe in house
treatment for concussion regardless of severity
step-wise return to play
sleep -> go to school -> homework -> practice -> play
abuse vs. neglect
abuse: + sxs, intentional, active
neglect: - sxs, absence, passive
risk factors for abuse: child
intellectual disability
premature birth
physical disability
cognitive disability
risk factors for abuse: parental
those who were abused
single parent
young parent
low SES
how to spot abuse: fractures
skull or clavicle
femur, especially spiral
rib fractures in infants
different stages of healing
how to spot abuse: bruises
different stages of healing
how to spot abuse: burns
feet, ankles (dunk)
buttocks only (dunk)
punctate circular burns (cigarettes)
how to spot abuse: sexual
any STD in any child ever
vaginal or anal trauma
how to spot abuse: behavior
not crying in the presence of a parent
running from caregiver
receiving comfort from healthcare provider rather than caregiver
what to do if you suspect abuse: certainty
certainty is NOT required
what to do if you suspect abuse: the family
tell the family why you are doing it and that you are required by law to do so
what to do if you suspect abuse: the child
hospitalize the child if no safe alternative exists
what to do if you suspect abuse: the abuser
separate abuser from child if obvious
separate parent-child unit from a common abuser
what to do if you suspect abuse: behavior
offer resources and support that allows families and caregivers to understand disease process, provide emotional, economic, and physical support
what to do if you suspect abuse: CPS
must report
ALTE definition
frightened observer plus any combination of:
- change in color: red, blue, or pale
- change in muscle tone: hypertonic or hypotonic
- change in respirations: choking, gagging, or apnea
features by etiology: seizures
eye deviation, limb-jerking
features by etiology: infection
temperature instability
fussy baby
features by etiology: cardiac
difficulty with feeding
murmur
FTT
features by etiology: abuse
evidence of trauma
femur, skull fracture
BRUE definition
< 1 y/o + < 1 min duration + …
- change in color: red, blue, or pale
- change in muscle tone: hypertonic or hypotonic
- change in respirations: choking, gagging, or apnea
- change in responsiveness
low risk BRUE
no history no physical no CPR 1st time, non-recurring age, term > 60d age, preterm >32wk GA AND >/= 45wk PC action: reassurance only
high risk BRUE
hx suggestive of disease physical suggestive of dz CPR performed multiple, recurring not old enough action: NO SET WORKUP, go after workup based on history and physical
SIDS prevention
back to sleep
don’t share a bed
smoking cessation
flatten occiput
erythema infectiosum path
parvovirus 19
erythema infectiosum pt
slapped-cheek rash
erythema infectiosum dx
clinical
erythema infectiosum tx
none
erythema infectiosum f/u
aplastic crisis in sickle cell
hydrops fetalis if in utero
measles path
measles virus (paramyxovirus)
measles pt
cough, coryza, conjunctivitis, Koplik spots
fever AND rash
- starts on face, spreads to extremities
measles tx
supportive (ppx vaccinate)
measles f/u
subacute sclerosing panencephalitis
rubella path
rubella
rubella pt
fever BEFORE rash
starts on face, spreads to toes
prodrome of lymphadenitis
rubella tx
supportive (ppx vaccinate)
rubella f/u
congenital: heart, deafness, cataracts
roseola path
HHV-6
roseola pt
fever BEFORE rash (>104)
starts on trunk, spreads outward
roseola f/u
febrile seizures
varicella chickenpox path
varicella zoster
varicella chickenpox pt
widespread
vesicles on erythematous base
different stages of healing
varicella chickenpox tx
supportive, antivirals for teens and those with lung issues (ppx vaccinate)
varicella chickenpox f/u
shingles
varicella shingles path
reactivated varicella, non-vaccinated adults
varicella shingles pt
pain precedes rash
vesicles on an erythematous base
does NOT cross midline
confined to a dermatome
varicella shingles tx
antiviral if immunocompromised (ppx vaccinate)
varicella shingles f/u
postherpetic neuralgia
mumps path
mumps virus
mumps pt
bilateral swelling
orchitis in pubertal males
mumps dx
clinical
mumps tx
vaccinate
mumps f/u
infertility
hand-foot-mouth path
coxsackie A
hand-foot-mouth pt
nonspecific prodrome
vesicle on erythematous base but only on the hands, feet, and mouth
hand-foot-mouth dx
clinical
molluscum contagiosum path
poxvirus
molluscum contagiosum pt
flesh-colored
central umbilication
trunk, arms, diaper
molluscum contagiosum dx
clinical
molluscum contagiosum tx
supportive
scarlet fever path
group A strep
scarlet fever pt
fever, sore throat
desquamating sandpaper rash
trunk and spreads outwards
scarlet fever dx
streptolysin O
scarlet fever tx
penicillin prevents rheumatic fever but not post-strep glomerulonephritis
anaphylaxis path
IgE mediated
life threatening
anaphylaxis pt
rash (urticarial) AND airway edema
HYPOTENSION
anaphylaxis dx
clinical
anaphylaxis tx
epi 1:1000 IM ‘epic-pen’ …
then H1/H2 blockers
then steroids
anaphylaxis f/u
avoid triggers
urticaria path
IgE mediated
rash only
urticaria pt
rash (urticarial)
- erythema
- wheal
NO hypotension
urticaria dx
clinical
urticaria tx
topical or oral antihistamines
avoidance of trigger
if anaphylaxis, treat that
angioedema path
non-IgE mediated swelling
medication induced
C1 esterase deficiency
angioedema pt
swelling can involve mouth, throat, tongue which makes it life-threatening
angioedema dx
clinical
angioedema tx
airway protection
stop the offending agent (ACE-i)
angioedema f/u
C1 esterase deficiency gets FFP
H1/H2 blockers and steroids probably don’t help
allergic rhinitis path
seasonal (dander/pollen exposure)
perennial (pets, dust, indoor mold)
allergic rhinitis pt
allergic shiners (dark eyes) allergic salute (nasal crease) pale, boggy mucosa polyps cobblestoning
allergic rhinitis dx
identify and remove triggers - pets - carpets - parents smoking skin testing if severe or refractory to trigger
allergic rhinitis tx
avoid triggers
antihistamines
- mild-moderate = 2nd gen (loratadine, fexofenadine, cetirizine)
- moderate-severe = intranasal corticosteroids
allergic conjunctivitis path
same as rhinitis
allergic conjunctivitis pt
same s rhinitis, except it’s the eyes
- injection
- chemosis
- shiners
allergic conjunctivitis dx
clinical
allergic conjunctivitis tx
avoid triggers
mast cell stabilizers and antihistamines instead of intranasal steroids
food allergens path
triggers:
- outgrows: wheat, soy, milk, eggs
- for life: nuts, shellfish, seafood
food allergens pt
atopic dermatitis
n/v/d
anaphylaxis possible (nuts, shellfish)
food allergens dx
food trial
food allergens tx
epipen for anaphylaxis
avoidance of trigger
milk protein allergy path
soy/formula
milk protein allergy pt
n/v/d
bloody bowel movements
FTT
milk protein allergy dx
clinical
milk protein allergy tx
cow’s milk formula or breastfeed
acute otitis media path
URI bugs = strep, moraxella, H. flu
middle ear
acute otitis media pt
unilateral ear pain
relief of pain on pulling pinna
loss of light reflex
erythema, tympanic effusion
acute otitis media dx
pneumatic insufflation
acute otitis media tx
1st: amoxicillin
recur: amoxicillin-clavulanate
re-recur: tympanoplastic
PCN allergy: cefdinir -> azithromycin
acute otitis media f/u
mastoiditis
acute otitis externa path
outer ear
swimmer’s = pseudomonas
digital = staph aureus
acute otitis externa pt
unilateral ear pain
NO relief of pain on pulling pinna
angry erythematous canal
acute otitis externa dx
clinical
acute otitis externa tx
spontaneously resolves
acute otitis externa f/u
toxic, malignant otitis externa, use cipro and steroid ear drops
mastoiditis path
complications of ear infections
mastoiditis pt
acute otitis media AND
posterior bulging of mastoid
anteriorly rotated ear
mastoiditis dx
clinical… CT scan (not needed)
mastoiditis tx
surgical drainage
bacterial sinusitis path
URI bugs (same as AOM)
bacterial sinusitis pt
congestion
bilateral purulent rhinorrhea
facial tap = pain
bacterial sinusitis dx
clinical
XR - air fluid levels (not necessary)
CT - opacification (not necessary)
bacterial sinusitis tx
supportive EXCEPT - temp >/= 38 deg C - worsening - duration > 10d amoxicillin + clavulanate
bacterial sinusitis f/u
CT scan for recurrence
foreign body for young kid
common cold path
rhinovirus, transmitted by large droplets
common cold pt
congestion, non-toxic
<10d, no purulence
common cold dx
clinical
common cold tx
supportive
pharyngitis path
viral (mc)
group A strep (rheumatic fever)
pharyngitis pt
sore throat, odynophagia Cough (absent) + 1 Exudates + 1 Nodes (adenopathy) + 1 Temp >/= 38 + 1 OR age <14 + 1 OR age > 44 - 1
pharyngitis dx
<1: supportive
2-3: rapid strep (culture or treat)
>/=4: treat as strep
pharyngitis tx
amoxicillin or PCN
foreign bodies path
kids stick things places
foreign bodies pt
unilateral purulent discharge
unilateral otitis externa
aspiration
foreign bodies dx
clinical, cxr
foreign bodies tx
retrieval
foreign bodies f/u
if insect gets in:
- lidocaine and retrieval
epistaxis path
digital trauma (nose picking)
epistaxis pt
unilateral bleeding, <30mins
epistaxis dx
clinical
epistaxis tx
ice pack, lean forward
cauterize anterior bleeds
pack posterior bleeds
choanal atresia path
atresia or stenosis of passage from nose to throat
choanal atresia pt
blue while feeding, pink while crying, childhood snore
choanal atresia dx
catheter fails to pass through the nose
choanal atresia tx
scope and surgery
croup path
parainfluenza
croup pt
3mo-3y
viral prodrome precedes
seal-like barking cough interspersed with stridor
croup dx
clinical
XR - steeple sign
croup tx
mild: misting
moderate: racemic epi, steroids, O2
severe: admit for O2 support
bacterial tracheitis path
strep and staph
bacterial tracheitis pt
5-7y/o
croup that doesn’t get any better with croup tx
also more insidious
bacterial tracheitis dx
clinical
tracheal culture
bacterial tracheitis tx
IV abx
bacterial tracheitis f/u
ENT to bronch/scope/get tracheal culture
epiglottitis path
Hib (Hib vaccine has dropped incidence)
epiglottitis pt
6-12 y/o, unvaccinated SICK rapid onset high spiking fevers drooling, tripoding accessory muscles hot-potato-voice ('muffled')
epiglottitis dx
clinical
direct visualization of cherry-red epiglottitis during airway
XR - thumbprint
epiglottitis tx
secure airway in the OR
- do not touch the epiglottis
IV abx after airway secured = cefuroxime, ceftriaxone
retropharyngeal abscess path
oral flora
URI bugs
retropharyngeal abscess pt
SICK rapid onset high spiking fevers drooling, neck extended hot-potato-voice ('muffled') * unilateral anterior chain nodes * * tender palpable mass *
retropharyngeal abscess dx
CT scan max/face/neck
retropharyngeal abscess tx
incision and drainage, IV abx
peritonsillar abscess path
oral flora
URI bugs
peritonsillar abscess pt
> 10 y/o
hot-potato-voice (‘muffled’)
drooling, sore throat
* uvular deviation *
peritonsillar abscess dx
clinical
peritonsillar abscess tx
I&D, IV abx
foreign body aspiration path
kids put things places
foreign body aspiration pt
sudden onset dyspnea
unsupervised child
stridor = extrathoracic
wheeze = intrathoracic
foreign body aspiration dx
1st: CXR PA and lateral
- coin sign AP r/o trachea
- coin sign lateral nonspecific
best: rigid bronchoscope
foreign body aspiration tx
retrieval
FB aspiration f/u
high risk:
- kids < 3y/o
- foods: peanuts, M&Ms, hot dogs
asthma path
reversible obstructive lung disease
asthma pt
wheezing, dyspnea during attacks
normal between attacks
asthma, allergy, atopy
asthma dx
PEFTs
- decrease FEV1/FVC
- reversible with bronchodilators
- inducible with methacholine
asthma tx
chronic escalation - SABA - SABA + ICS - SABA + incr ICS - SABA + incr ICS + LABA ... add steroids ... LTA are oral adjuncts acute exacerbation - peak flow before and after - albuterol/ipratropium - IV steroids - maybe magnesium - maybe subQ epi
asthma f/u
remove allergens
- pets
- carpets
- smoking (parents)
pneumonia path
typical, atypical, viral
pneumonia pt
pre-school = viral
school or older = bacterial
fever, cough, consolidation on CXR
pneumonia dx
cxr
pneumonia tx
amoxicillin or azithromycin
pneumonia f/u
internal medicine - infectious ID
bronchiolitis path
inflammatory disorder of small airways
viral infection = RSV
bronchiolitis pt
very young < 2y/o
trouble feeding
bronchiolitis dx
cxr (normal)
rapid antigen testing from a nasopharyngeal swab (yes, but don’t)
bronchiolitis tx
supportive - IVF/NG feeds, oxygen
NO: steroids, ß-agonists, antibiotics
bronchiolitis f/u
RSV bronchiolitis is all supportive care
nothing works: just get the kids through it
cystic fibrosis path
CFTR or CCTR mutation
autosomal recessive
cystic fibrosis pt
prenatal screen positive - most dx no prenatal screen (immigrant) - FTT - meconium ileus - frequent respiratory infections - baby has salty skin
cystic fibrosis dx
sweat chloride test
- > 40 neonates
- > 60 in others
cystic fibrosis tx
pulmonary toilet
pneumonia = pseudomonas
vit ADEK
pancreatic enzymes
cystic fibrosis f/u
short stature
limited life expectancy
necrotizing enterocolitis path
dying gut
necrotizing enterocolitis pt
premature neonate in ICU
bloody BM
necrotizing enterocolitis dx
xray = pneumonitis intestinalis
necrotizing enterocolitis tx
NPO, IVF, TPN
IV abx
necrotizing enterocolitis f/u
other diseases of prematurity
anal fissure path
tear in anal mucosa
anal fissure pt
visual inspection
iatrogenic in the neonate, well baby
anal fissure dx
clinical
anal fissure tx
reassurance
babies are incontinent of stool, the stool is soft, and it will heal spontaneously
intussusception path
telescoping of bowel
vascular compromise
intussusception pt
abrupt onset colicky pain knee-chest position = relief * sausage-shaped mass in RUQ * * currant jelly stool * (too late)
intussusception dx
xray = perforation, obstruction
u/s = target sign (aka donut)
air-enema best test
intussusception tx
air-enema usually curative surgery if: - peritoneal - perforation - failed air-enema
intussusception f/u
90% kids have no lead point
90% adults have a mass lead point
meckel’s diverticulum path
remnant of the vitelline duct = gastric mucosa
omphalomesenteric duct
meckel’s diverticulum pt
'colon caner' at 2 y/o - painless, intermittent hematochezia - iron deficiency anemia - FOBT + rule of 2s - < 2 y/o at dx - < 2% of population - 2x boys:girls - 2ft from ileocecal valve - 2in in length
meckel’s diverticulum dx
mocker’s scan = technetium-99
meckel’s diverticulum tx
surgery
meckel’s diverticulum f/u
teenagers get diagnosed with CT scans
distractors - reassurance only
swallowed maternal blood = apt test, Selena after delivery
swallowed self blood = epistaxis history
dietary = iron, beets, medication
Crohn’s
watery diarrhea, weight loss, fistulas
EGD + colon = skip lesions
meds to control
surgery only for fistulas
UC
bloody diarrhea
colon = continuous lesions
hemicolectomy curative
@8y/o, q1y colonoscopy until resected
infectious colitis
fever and blood BM
lactoferrin, WBC, stool culture
milk-protein allergy
change to hydrolyzed formula
left-to-right shunts
increase pulmonary flow increase pulmonary vasculature on xray increase pulmonary pressures RVH Eisenmenger's (reversal to right to left) "D" diseases: ASD, VSD, PDA
atrial septal defect path
ostium primum (rare) ostium secundum (more common)
atrial septal defect pt
fixed split S2
mc murmur > 1 y/o
atrial septal defect dx
echo
atrial septal defect tx
surgical closure
ventricular septal defect path
hole between the two ventricles
VSD pt
harsh holosystolic murmur in a neonate…but the worst defects have no murmur
mc congenital heart disease
- likely get fixed or die before 1 yr
FTT, down syndrome
VSD dx
echo
VSD tx
if CHF, FTT, dyspnea = fix now
if none of those things = fix only if increased pulmonary blood flow
VSD f/u
surgical closure likely required, may spontaneously resolve
PDA path
ductus arteriosus remains open, a connection between aorta and pulmonary artery
PDA pt
continuous machinery-like murmur
PDA dx
echo
PDA tx
if no CHF -> indomethacin = Ends the PDA (preterm infants only)
if yes CHF -> surgical closure
if cyanotic defect -> prostaglandins to sustain PDA
PDA f/u
close as necessary, but many that persist are clinically significant
right to left shunt
decrease pulmonary flow decrease pulmonary vasculature on xray deoxygenated blood in periphery blue baby syndrome fatal if not corrected the "T" diseases: tetralogy, TGA, TA, TAPVR
tetralogy of fallot path
- overriding aorta
- pulmonary stenosis
- RVH
- VSD
“endocardial cushion defect”
tetralogy of fallot pt
mc cyanotic disease of children because TGA babies die or get fixed
‘tet spells’ cyanosis relieved by squatting
tetralogy of fallot dx
1st: boot shaped heart on xray
best: echocardiogram
tetralogy of fallot tx/
surgical correction
tetralogy of fallot f/u
associated with Down’s syndrome
transposition of the great arteries path
heart fails to twist
pulmonary artery and vein both connected to the left heart and lungs
aorta and vena cava both connected to the right heart and periphery
TWO separate circulatory systems connected only by ductus arteriosus
transposition of the great arteries pt
blue baby day 1 - you will not miss this
mom is diabetic at the start of pregnancy
transposition of the great arteries dx
clinical: blood pressures in all extremities
xray shows rib-notching (not diagnostic)
aortogram
transposition of the great arteries tx
surgical correction
developmental dysplasia of the hip age
newborn
developmental dysplasia of the hip pt
clicky hip during the neonatal evaluation, Ortolani and Barlow maneuvers
developmental dysplasia of the hip dx
u/s @ 4-6wks
developmental dysplasia of the hip tx
harness
Legg-Calve-Perthes age
6
Legg-Calve-Perthes pt
insidious onset antalgic gait
Legg-Calve-Perthes dx
xray
Legg-Calve-Perthes tx
cast
slipped-capital femoral epiphysis age
13
slipped-capital femoral epiphysis pt
fat kid going through a growth spurt
non-traumatic knee pain
slipped-capital femoral epiphysis dx
frog-leg xray
slipped capital femoral epiphysis tx
surgery (urgently)
septic hip age
any age
septic hip pt
fever and joint pain, especially after another febrile illness or unprotected sex
septic hip dx
arthrocentesis (> 50,000 wbc)
septic hip tx
drainage and abx
transient synovitis age
any age
transient synovitis pt
4-6wks after a viral illness
joint pain WITHOUT fever, leukocytosis, inflammatory markers
transient synovitis dx
history
transient synovitis tx
supportive
osgood-schlatter’s disease path
osteochondrosis
osgood-schlatter’s disease pt
teenage athlete with knee pain, swelling and eventually palpable nodule on the tibia
osgood-schlatter’s disease dx
clinical
osgood-schlatter’s disease tx
rest + cast (aka stop exercising, curative)
work thorugh it (palpable nodule)
scoliosis path
spinal deformity (left to right) - not lordosis, not kyphosis
scoliosis pt
teenage girl who can present with either:
moderate: cosmetic
severe: SOB
scoliosis dx
Adam’s test is positive (have the girl lean forward and see asymmetry)
scoliosis tx
no therapy
brace
surgery with rods
osteogenic sarcoma path
retinoblastoma gene, associated with retinoblastoma of the eye
osteogenic sarcoma pt
bone pain in a pre-teen/teenager
retinoblastoma at birth (neonatal)
osteogenic sarcoma dx
1st: xray = distal femur, sunburst pattern
then: MRI
best: biopsy
osteogenic sarcoma tx
surgery
fx in kids path
fx can occur for any reason
trauma, fall, and child abuse
you must think of the growth plate, a consideration not in adults
fx in kids pt
leg pain, trauma
fx in kids dx
xray
fx in kids tx
involves growth plate -> ORIF
does not involve growth plate -> cast
Ewing’s sarcoma path
translocation t(11;22)
Ewing’s sarcoma pt
bone pain in a pre-teen/teenager
no risk factor
Ewing’s sarcoma dx
1st: xray = midshaft, onion-skin pattern
then: MRI
best: biopsy
Ewing’s sarcoma tx
surgery
special considerations for peds fractures: external fixation
closed, simple, aligned
no growth plate
special considerations for peds fractures: open reduction and internal fixation
comminuted angular displaced open or involves the growth plate
sickle cell disease path
HgbSS - autosomal recessive
valine for glutamic acid on 6th position
sickle cell disease pt
asplenism vasoocclusive crisis chronic pain chronic anemia pigmented gallstones
sickle cell disease dx
sickle cells on smear
Hgb electrophoresis
sickle cell disease tx
hydroxyurea (increase HgbF)
iron, folate
PCN until age 5
sickle cell disease f/u
hemosiderosis from transfusions = deferoxamine/deferasirox
asplenism = pneumovax
avascular necrosis of the hip = conservative attempted -> surgery
vasoocclusive crisis path
sickling cells = ischemia and hemolysis
vasoocclusive crisis pt
acute pain
elevated bilirubin, elevated reticulocytes
jaundice
vasoocclusive crisis dx
blood smear = sickled cells
vasoocclusive crisis tx
IVF, pain control
indications for exchange transfusion in sickle
priapism focal neurologic deficit, stroke acute chest (chest pain, pulmonary edema)
sickle variants
HgbS-ßo the worst HgbSS sickle cell disease HgbS-ß+ milder HgbSC almost not a disease HubS trait not a disease (carrier)
consideration of complications in sickle: asplenism
PCN until 5
vax for strep
consideration of complications in sickle: iron overload
deferoxamine
consideration of complications in sickle: avascular necrosis
conservative then surgery
consideration of complications in sickle: sickled HgbSS
hydroxyurea
consideration of complications in sickle: anemia
folate
consideration of complications in sickle: pain
analgesics (opiates)
consideration of complications in sickle: osteomyelitis
staph first, then salmonella
chemical conjunctivitis
24hrs
non-purulent
bilateral
tx: observation (caused by silver nitrate ppx)
gonorrhea conjunctivitis
day 2-5
purulent
bilateral, check for systemic illness
tx: ceftriaxone IM
chlamydia conjunctivitis
day 5-14
mucho-purulent
unilateral, then bilateral; associated with pneumonia
tx: erythromycin PO, no topical antibiotics
retinoblastoma path
Rb gene mutation
retinoblastoma pt
newborn screen in the neonatal unit with an abnormal light reflex
retinoblastoma dx
red reflex (normal) = pure white retina white thing in the back of the eye
retinoblastoma tx
surgery
retinoblastoma f/u
osteosarcoma
amblyopia path
cortical blindness
amblyopia pt
strabismus, cataracts, another cause, leads to cortical blindness
amblyopia dx
none
amblyopia tx
none
fix the problem that could lead to cortical blindness
strabismus path
lazy eye
strabismus pt
baby with one eye that focuses while the other does not
almost ALWAYS a photograph question
strabismus dx
light reflects at different points in both eyes
strabismus tx
if present at birth
- patch the good eye
- surgery if all else fails
glasses if developed after birth
congenital cataracts path
present at birth -> TORCH infections
not present at birth -> galactosemia
congenital cataracts pt
white cloudy lesions in front of their eye ‘white thing in FRONT of the eye’
congenital cataracts dx
clinical
congenital cataracts tx
surgical removal
retinopathy of prematurity path
premature baby, oxygen toxicity
retinopathy of prematurity pt
suspect in any premature neonate, especially if any of the ‘other 3’ are present
retinopathy of prematurity dx
ophtho exam = growths on retina
retinopathy of prematurity tx
laser ablation
retinopathy of prematurity f/u
the ‘other three’
- necrotizing enterocolitis
- bronchopulmonary dysplasia
- intraventricular hemorrhage
posterior urethral valves path
difficulty getting urine out
redundant tissue
posterior urethral valves pt
no urinary output + distended bladder, day 0 of life
+/- oligohydramnios (prenatal u/s)
+/- incr Cr (mom clears)
posterior urethral valves dx
U/S = hydro catheter = large volume diuresis VCUG = negative reflux
posterior urethral valves tx
catheter = relieve obstruction surgery = resolve problem
hypospadias/epispadias path
the scrotum ‘zips up’ lopsided
hypo = under = ventral urethra
epi = top = dorsal urethra
hypospadias/epispadias pt
cosmetic deformity
epi can lead to incontinence
hypospadias/epispadias dx
clinical
hypospadias/epispadias tx
NEVER CIRCUMCISE
rebuild using foreskin
ectopic ureter path
one good ureter = normal function
one janky ureter = consent leak
ectopic ureter pt
boys: asymptomatic
girls: ‘normal’ bladder function AND constant leak
ectopic ureter dx
U/S: no hydro
VCUG: no reflux
radionucleotide scan for renal function
ectopic ureter tx
reimplant
vesicoureteral reflux path
retrograde flow to ureters
bacteria ascend
vesicoureteral reflux pt
prenatal u/s = hydro
recurrent UTI/pyelo at young age
vesicoureteral reflux dx
u/s = hydro VCUG = reflux
vesicoureteral reflux tx
low grade = abx
ultimately = surgery
why do u/s for uro
hydro or no hydro
why do VCUG for uro
reflux or no reflux
why do CT scan for uro
extraluminal lesions (IV contrast)
trauma (IV contrast)
nephrolithiasis (no contrast)
why do cystoscopy for uro
intraluminal lesions
stent intervention
why do IVP for uro
never the right answer
microscopic hematuria
likely self-limiting, investigate if persists
dysmorphic RBC, RBC casts hematuria
glomerulonephritis, lean on the U/A and maybe biopsy (nephritic syndrome)
normal RBC, no casts hematuria
post-glomerulonephritis
work-up involves CT or cystoscopy or both
lots of blood, no RBCs hematuria
rhabdomyolysis
hematuria and blunt trauma hematuria
CT scan with IV contrast
cryptorchidism path
undescended testes
cryptorchidism pt
absent testes on physical exam
cryptorchidism dx
clinical
cryptorchidism tx
newborn: if undescended by 6mo, surgically bring down
prepubertal: surgically tether
postpubertal: surgically remove
cryptorchidism f/u
monitor for testicular cancer
- increase risk x10
absence seizure path
hundreds of brief seizures without post-octal state
absence seizure pt
ADHD symptoms
- trouble in school
- trouble paying attention
absence seizure dx
EEG
absence seizure tx
ethosuximide
absence seizure f/u
will outgrow eventually
febrile seizure path
peak temp/rate of rise (doesn’t matter)
febrile seizure pt
five months to five years first time seizure fever and a seizure no focal features (simple) fifteen minutes or less (simple)
febrile seizures dx
clx
febrile seizures tx
treat underlying cause
west syndrome path
unknown
west syndrome pt
around 6mo old
bilateral jerking head or extremities
NO FEVER
west syndrome dx
interictal EEG = hypsarrhythmia
west syndrome tx
ACTH
west syndrome f/u
psychomotor retardation
lennox-gastaut path
comes from other causes
- west, tuberous sclerosis, brain injury of some kid
lennox-gastaut pt
1-7 y/o; recurrent seizures
lennox-gastaut dx
interictal EEG: spike and wave
lennox-gastaut tx
valproate, rufinamide
lennox-gastaut f/u
psychomotor and intellectual disability
tuberous sclerosis path
brain tubers
tuberous sclerosis pt
< 2 years
afebrile seizures
tuberous sclerosis dx
ash leaf spots on Wood’s lamp
CT scan on tubers
tuberous sclerosis tx
organ specific - think seizures
tuberous sclerosis f/u
monitor for organ involvement - brain, eyes, heart, psych
B cell immunodeficiencies
x-linked agammaglobulinemia of bruton
CVID
IgA deficiency
Hyper- IgM
phagocytic immunodeficiencies
leukocyte adhesion deficiency
chronic granulomatous disease
T-cell immunodeficiencies
DiGeorge
combined immunodeficiencies
wiskott-aldrich
ataxia-telangiectasia
SCID
complement immunodeficiencies
c1 esterase deficiency
C5-C9 MAC attack
x-linked agammaglobulinemia of Bruton path
x-linked
A-Ig-enemia
decrease B cells = Boys
x-linked agammaglobulinemia of Bruton pt
sinopulmonary infections, 6 mo
x-linked agammaglobulinemia of Bruton dx
CBC = normal
QIg = no IgA, no IgG, no IgM
flow = no B cells
BTK gene
CVID path
mild XLA
CVID pt
mild XLA in teenager
CVID dx
CBC = normal QIG = decrease 2/3 Ig
CVID tx
schedule IgG …. BM transplant
IgA deficiency path
decrease IgA -> decrease mucosal
IgA deficiency pt
- sinopulmonary + GI bugs
2. asx … pRBC … anaphylaxis
IgA deficiency dx
CBC = normal
QIG: decrease IgA, increase IgG, increase IgM
IgA deficiency tx
none
IgA deficiency f/u
anaphylaxis
hyperIgM path
isotope switching fails
hyperIgM pt
immune decrease, bacterial infections
hyperIgM dx
CBC = normal
QIG: decrease IgA, decrease IgG, dramatic increase IgM
hyperIgM tx
none
hyperIgM f/u
anaphylaxis
leukocyte adhesion deficiency path
wbc can’t leave blood
leukocyte adhesion deficiency pt
toxic but NO PUS
delayed separation from cord
leukocyte adhesion deficiency tx
biopsy
chronic granulomatous disease path
no respiratory burst, macrophages
eat, but not kill catalase +
chronic granulomatous disease pt
staph abscess
chronic granulomatous disease dx
** nitro blue **
CBC = increase wbc
QIG = Increase IgM, increase IgG
chronic granulomatous disease tx
BMT
DiGeorge path
22q11.2 deletion
3rd pharyngeal pouch
DiGeorge pt
wide-spaced eyes low-set ears absent thymic shadow small face fungi + PCP
DiGeorge dx
syndrome: clinical
CBC = decrease ALC
DiGeorge tx
TMP-SMX ppx
IVIG bridge
thymic transplant
DiGeorge f/u
decrease calcium, secondary PTH
tetany, seizures
wiskott-aldrich path
x-linked boys
wiskott-aldrich pt
eczema + decreased platelet + normal infections
wiskott-aldrich dx
CBC = decrease wbc, decrease platelet QIG = increase IgA, increase IgE
wiskott-aldrich tx
bone marrow transplant
ataxia telangiectasia
ataxia, telangiectasia, decrease immune
DNA repair, leukemia, lymphoma
SCID path
no immune system, no defense
No B, No T
adenosine deaminase
SCID pt
mega-AIDS from birth
SCID dx
CBC = decrease wbc QIG = no IgA, no IgM, no IgG
SCID tx
isolate from everything
… TMP-SMX against PCP
… BM transplant
C1 esterase deficiency
angioedema
FFP
C5-C9 Mac attack
neisseria