Pulmonary Normal Physiology, Response to Exercise & Abnormal Physiology Flashcards

1
Q

Normal SpO2 =
Normal PaO2 =
Normal Respiratory Rate =

A

95-100%
80-100 mmHg
12-18 breaths/min

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2
Q

SpO2:
– percentage of ____ bound to O2
– how do you measure?
– measures:
– exact/not exact measurement?

A

– Hgb
– pulse ox –> non invasive
– how much O2 is being delivered to tissues
– not as exact

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3
Q

PaO2:
– partial pressure of dissolved ____ in arterial blood
– how do you measure?
– reflective of:
– exact/not exact measurement?

A

– O2
– requires arterial blood gas lab draw
– the balance of O2 delievery and consumption
– most accurate way to determine effectiveness of blood oxygenation

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4
Q

true or false. normal respiratory rate has regular rhythm with non-labored effort, tidal volume is ~500 mL and no audible sounds are heard.

A

true

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5
Q

what is eupnea?

A

normal breathing rate and pattern

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6
Q

cardiac biomarkers:
– lab value is ____
– normal value:
– indication?

A

– BNP
– < 100 pg/mL
– released in response to ventricular stretch or worsening heart failure

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7
Q

CBC:
– lab value used in pulmonary:
– normal range:
– indication:

A

– hemoglobin (Hgb)
– M: 14-18 ; F: 12-16
– Transports O2

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8
Q

arterial blood gases:
– pH normal:
– PaO2 normal:
– PaCO2 normal:
– HCO3:
– indication for drawing blood gases?

A

– 7.35-7.45
– 80-100 mmHg
– 35-45 mmHg
– 22-26 mEq/L
– all portions that control normal blood chemistry for optimal physiologic function

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9
Q

what is normal SpO2 response during exercise?

A

initially: transient drop when exercise starts –>
with increasing workload: increase in respiratory rate brings SpO2 back to stable/normal levels

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10
Q

what may happen to SpO2 with long duration exercise once steady state is reached?

A

SpO2 may increase

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11
Q

should SpO2 fluctuate greatly with a normal response to exercise?

A

no

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12
Q

what is normal respiratory rate response to exercise?

A

gradual increase with increased workload
rapid rise after anaerobic threshold is reached (VT2)

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13
Q

does respiratory rate fluctuate during exercise once steady state has been reached?

A

no - minimal change should happen

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14
Q

what is normal lung volume response to exercise?

A

increases linearly with increasing workload

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15
Q

tidal volume ___(increases/decreases)___ to meet demands of exercise and can approach _______ volumes

A

increases ; vital capacity (VC)

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16
Q

describe the normal physiological progression of respiration due to exercise:

A

respiration increases –> more O2 used, increased CO2
brain detects increase in CO2 –>
CNS signals lungs to increase RR –>
inc. RR & lung volume leads to inc. gas exchange –>
CNS signals heart to inc HR –> so more blood is pumped to lungs for gas exchange –>
inc. O2 is sent to muscles to balance inc. demand –>
increased CO2 is blown off from inc. RR

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17
Q

Abnormal SpO2 =
Abnormal RR =
Abnormal HR =
Abnormal BP =

A

< 90% at rest, acute change in O2 demand/device
< 10 or > 30 / min. at rest ; unable to maintain conversation
< 50 or > 120 at rest ; uncontrolled/new arrhythmia
> 180/90 or < 90/60 or MAP < 60

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18
Q

what could cause hypoxemia/hypoxia in a patient?

A

heart/lung disease
hypoventilation
infection
anemia
carbon monoxide poisoning
pulmonary embolism
V/Q mismatch
sleep apnea
airway obstruction
high altitude

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19
Q

what is Hypoxemia?

A

low blood O2 levels measured by SpO2 or PaO2
** low O2 in blood

20
Q

symptoms of hypoxemia?

A

headache
dyspnea
tachycardia
coughing
wheezing
confusion, AMS
Cyanosis of fingers or lips

21
Q

what is hypoxia?

A

under-oxygenation of tissues that impair cellular metabolism
** low O2 in tissues
** worse! Reg flag

22
Q

symptoms of hypoxia?

A

restlessness
headache
confusion, AMS
tachycardia
anxiety
tachypnea, dyspnea

23
Q

symptoms of severe hypoxia?

A

bradycardia
extreme restlessness
cyanosis
passing out

24
Q

abnormal breathing patterns:
bradypnea =
tachypnea =
apnea =
hyperpnea =
cheyne-stokes =
agonal =

A

– dec. RR
– inc. RR
– absence of breathing
– normal rate but deep respirations
– gradual increase and decrease in respirations with periods of apnea
– apnea with periods of inconsistent respirations

25
causes of abnormal breathing patterns: bradypnea = tachypnea = apnea = hyperpnea = cheyne-stokes = agonal =
-- sleep, drugs, metabolic disorder, CVA/ABI -- fever, anxiety, shock, exercise, pathology -- not alive -- emotional stress, diabetic ketoacidosis -- inc. intracranial pressure, brainstem injury -- actively dying, severe CVA/ABI
26
what are abnormal restrictive lung volumes?
decreased vital capacity and total lung capacity
27
with restrictive lung volume, what are the biggest limitations to functional endurance?
dec. inspiratory reserve volume (IRV - breath in) and dec. expiratory reserve volume (ERV - breath out)
28
what are abnormal obstructive lung volumes?
increased vital capacity and total lung capacity
29
with obstructive lung volume, what are the biggest limitations to functional endurance?
increased ERV and residual volume (RV)
30
what is an abnormal SpO2 response to exercise?
persistent and/or ongoing drop in O2 with increasing workload AND increasing supplemental O2 delivery to maintain homeostasis
31
what is the physiologic implication of drop in O2 with increasing workload?
ischemia to muscles that need to be working while performing exercise
32
what is important to know before making clinical decisions to stop activity or reduce intensity?
individual patient O2 goals
33
what is an abnormal RR response to exercise?
drop in RR --> there are no normal scenarios that RR drops with increasing workload AND rapid increase in RR that does not match intensity of workload
34
how do you monitor how close your patient is to their VT2?
maintain ongoing conversation
35
what are basic principles of O2 delivery? - supplementing ____ - observe: - maintain: - awareness in ability to __
- supplementing hypoxemia with added O2 to keep SpO2 within safe limits - observe trends and amounts of supplemental O2 - be able to maintain supplemental O2 for patient during mobility - awareness of PT role in ability to titrate/adjust O2
36
is it within PT scope of practice to adjust supplemental O2?
no - O2 is considered a medication
37
what is: -- flow rate? -- concentration?
-- how fast air is being delivered, expressed in L/min -- FiO2 of O2, expressed in % (how much of that air is O2) ---> the faster the FiO2, the faster it needs to be delivered
38
what is FiO2? -- what is atmospheric air FiO2?
fraction of inspired oxygen (FiO2) = percentage of inhaled air that is O2 -- 21%
39
how do we determine how much oxygen our patient is on?
every 1 L/min above room air adds ~4% FiO2 ex: pt on 2 L O2 --> 2x4% = 8% + 20% = 28% ** 20% is atmospheric air
40
Nasal cannula: -- amount -- requires humidification?? -- can only change ____
-- 1-6 L/min "low flow" -- does not require added -- flow rate
41
face mask: -- amount: -- requires humidification?? -- can only change ____
-- 6-12 L/min -- does not -- flow rate
42
high flow nasal cannula: -- amount? -- requires ___ -- how do we ensure it reaches the pt?
-- 6-15 L/min for some types -- humidification added since air is moving faster -- inner lumen of cannula is patterned to direct high air flow
43
heated high flow nasal cannula: -- amount? -- what helps protect airways and keep secretions thin?
-- up to 60 L/min and 100% FiO2 -- heated humidifications
44
venturi mask: -- amount? -- sets flow based on ____ -- can only titrate:
-- up to 60% FiO2 -- FiO2 -- FiO2
45
Non-Rebreather device: -- amount? -- how does oxygen get delivered?
-- 1-15 L/min -- mask covers nose and mouth to deliver very high O2 concentration One way valves allow escape of exhaled CO2 to allow pure O2 on next inhalation