Pulmonary Clinical Medicine IV: Pneumothorax, TB, and Sarcoidosis Flashcards

1
Q

What is pneumothorax defined as?

A

Acute onset of unilateral chest pain and dyspnea

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2
Q

How is a pneumothorax diagnosied?

A

Presence of pleural air on CXR

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3
Q

Which category of pneumothorax occurs in the absence of an underlying lung disease?

It is thought to occur from?

A

1) Primary spontaneous pneumothorax

2) Rupture of subpleural apical blebs in response to high negative intrapleural pressures

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4
Q

Which category of pneumothorax is a complication of preexisting pulmonary disease?

A

Secondary spontaneous pneumothorax

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5
Q

Which category of pneumothorax usually occurs in the setting of penetrating trauma, lung infection, cardiopulmonary resuscitation, or positive-pressure mechanical ventilation?

A

Tension pneumothorax

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6
Q

What should be suspected in the presence of marked tachycardia, hypotension, and mediastinal or tracheal shift?

A

Tension pneumothorax

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7
Q

What can be performed for a spontaneous primary pneumothorax that is large or progressive?

A

Aspiration drainage of pleural air with a small-bore catheter

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8
Q

Patients with secondary pneumothorax, large pneumothorax, tension pneumothorax, or severe symptoms or those who have a pneumothorax on
mechanical ventilation should undergo?

A

Chest tube placement

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9
Q

How is pulmonary tuberculosis diagnosed on CXR?

A

Apical pulmonary opacities

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10
Q

Which phase of TB is clinically and radiographically silent?

A

Primary phase

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11
Q

Individuals with what type of tuberculosis infection do not have active disease and cannot transmit the organism to others?

A

Latent tuberculosis infection

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12
Q

What can cause increased risk of reactivation of TB?

A

1) Gastrectomy
2) Silicosis
3) DM
4) Immunocompromised

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13
Q

What are the risk factor for drug resistance strains of TB?

A

1) Immigration from countries with a high prevalence of drug-resistant tuberculosis
2) Close and prolonged contact with individuals with drug-resistant tuberculosis
3) Unsuccessful previous therapy
4) Nonadherence to treatment

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14
Q

Definitive diagnosis of TB depends on?

A

Sputum culture positive for M tuberculosis

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15
Q

What is encountered on imaging for TB in elderly patients?

A

Lower lobe infiltrates with or without pleural effusion

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16
Q

When is a miliary pattern (diffuse small nodular densities) of TB seen on imaging?

A

With hematologic or lymphatic dissemination of the organism

17
Q

Which patients usually display lower lung zone, diffuse, or miliary infiltrates; pleural effusions; and involvement of hilar and, in particular, mediastinal lymph nodes?

A

Immunocompromised patients, particularly those with late-stage HIV infection

18
Q

At what induration size is considered a positive TB skin test for HIV patients, those with recent contact with an infectious TB patient, and those with fibrotic changes on CXR suggestive of prior TB?

A

Greater than or equal to 5 mm

19
Q

At what induration size is considered a positive TB skin test for recent immigrants from countries with high prevalence, HIV-negative IV drug users, and children exposed to adults at high risk?

A

Greater than or equal to 10 mm

20
Q

What points to diagnosis of pulmonary sarcoidosis in a biopsy specimen?

(Highlighted in his slides)

A

Noncaseating granuloma

21
Q

What population is most at risk for sarcoidosis?

A

Black female