Pulmonary - Asthma Flashcards
What is the global intiative definition for asthma?
As a chronic airway inflammation
hx of respiratory sx like wheezes, SOB, chest tightness and cough that vary over time and in intensity
- toegher with variable expiratory airflow limitations
What are the sx of asthma?
wheezing
SOB
chest tighness
fatigue during exercise
poor athletic performance
avoiding activity
coughing - worse at night and early morning
Since asthma is an inflammatory response, the trigger leads to?
- narrow airways = bronchospasm
- increased secretions
- resistance to airflow and airtrapping on exhalation = hyperinflation
The medium-sized bronchi sustain the most what?
most pronounced physiological effects of the inflammation that’s associated with asthma
Over time, what does chronic inflammation lead to?
Remodeling of the airways
What are the risk factors of asthma?
- genetics
- sex
- environmental factors
- infections
- allergens
- obesity
Environmental - like smoke
allergens - house dust mites, mold
How does obesity increase the risk of asthma?
Due to the likely involvement of the inflammatory process in the lungs, adipose tissue and/or immune system
sx appear to be harder to control and responsiveness to standard pharm therapies are reduced
How is asthma diagnosed?
with spirometry
- because of the provocation with bronchoconstrictor agents and with bronchodilators for comparison
How is asthma diagnosis confirmed?
improvements in the sx with medical management with over time and repeated testing
results are reversible which helps guarantee asthma
What is the clinical presentation of asthma?
Decreased FEV1
Increased RV and FRC
What are the results of peak-flow meter indicate?
Green 80-100 = normal
Yellow 50-80 = airways are narrowing and treatment is warranted
Red < 50 = medical emergency
Asthma Severity
Intermittent
< 2x/wk - exacerbations are rare, nighttime sx
< 2x/month - does not interfere with normal activities
normal spirometry (>80%) when NOT having attack
Asthma Severity
Mild persistent
sx > 2x/wk
night time sx 3-4/months
attacks are more severe or interfere with activities
normal spirometry (>80%) when not having attack
Asthma Severity
Moderate persistent
Daily sx and use of daily meds
nighttime sx > 1x/wk but not daily
interferes with daily activities
abnormal spirometry > 60% but < 80%
Asthma Severity
Severe persistent
Continous sx day and night (night often every night)
activity is severely limited
exacerbations are frequent
abnormal spirometry 60% or less