Peripheral Artery Disease - PVD Flashcards
What are the risk factors?
- CAD/artheroscleorisis
- advanced age
- hypercholesterolemia
- smoking
- hypertension
- diabetes
- overweight
- family hx
What are the characteristics of patients with increasd risk of PAD?
- 65 years and over
- 50-64 with risk factors of artherosclerosis or family hx of PAD
- under 50 with DM and 1 risk factor for atherosclerosis
- with known atherosclerotic disease
- AAA - abdominal aortic aneurysm
Pathohysiology
What is the assumed cause?
mismatch of demands of the body’s organs and muscles with supply of O2
- this is because of atherosclerotic stenosis of peripheral arteries
reduced diameter of blood vessels = ischemia
Pathophsysiology
What occurs during exercise?
metabolism makes adenoside -> dilation of arterioles = increase blood flow to muscles
Pathophysiology
What is another factor that leads to ischemia?
obstructed arteries which can’t act well to vasodilation stimulus and blood flow
- dramatic reduction to exercise tolerance
Pathophysiology
Local adaptations to chronic ischemia will lead to changes in what?
Muscle fiber metabolism and skeletal muslce degeneration
Pathophysiology
What can lead to lower extremity weakness?
Physical and biomechanical changes
Pathophysiology
What does ischemic changes in multiple arteries lead to?
ischemic sx at rest (very similar to angina)
Clinical Presentation
What are the vessels most commonly affected?
- aorta
- iliac femoral
- popliteal
- tibialperoneal arteries
Clinical presentation
What vessels are affected if there is arm pain?
brachiocephalic or subclavian
Clinical Presentation
Where is intermittent claudication affected?
- buttock
- hip
- thigh
- calf pain
- sometimes feet and toes
Clinical presentation
What is the prevalence of intermitted claudication?
- only about 1/3 experience it
- about 1/3 experience atypical sx
- about 1/3 are asx
Clinical presentation
What are the atypical sx?
leg pain/carry on - able to keep exercising through the pain or pain that starts at rest w/o critical limb ischemia
Clinical Presentation
Where is the location of sx?
Distal to the stenotic artery
Chronic Presentation
Chronic ischemia leads to?
Ulceration, infection and skin necrosis
Clinical Presentation
What are the clinical presentation?
- dimished or absent pulses distal to stenosis
- muscle atrophy
- pallor or reduced temp when elevated (rubor of dependency)
- shiny, taut skin - typically with hair loss and brittle, thick, dry toenails (trophic changes)
- wounds
- gangrene
- necrosis of foot and digits
- reduced sensation
- associated with diabetes
ACSM Intermittent Claudication Scale
Grade 1
Definite discomfort or pain
- but only initial or modest levels
ACSM Intermittent Claudication Scale
Grade 2
Mod discomfort or pain from which the patient attention can be diverted
ACSM Intermittent Claudication Scale
Grade 3
Intense pain from which the patient’s attention can’t be diverted
ACSM Intermittent Claudication Scale
Grade 4
Excuciating and unbearble pain