Pulmonary Flashcards
What are the characteristics of intermittent asthma? (2; +TX)
- Symptoms <2 days/wk, brief exacerbations, nighttime symptoms <2 nights/month
- TX =only when sx occur, quick reliever med = SABA (albuterol), systemic oral steroids if needed during exacerbation
What are the characteristics of mild persistent asthma? (define and tx)
- Sx >2x/week but <1x/day, exacerbations affect activity, nighttime sx >2x/mo
- Tx: low dose inhalers steroid daily, ex. Flovent
Alternative = cromolyn, singulair, theophylline, +SABA for acute exacerbations (Albuterol)
What are the characteristics of moderate persistent asthma (define and tx)
- Daily sx, exacerbations are long and severely affect activity level, sx >1x wk at night
- TX = medium dose inhaled steroid and long-acting B2 agonist, alt=singulair or theophylline +SABA (albuterol) for acute sx + systemic steroids if needed
What are the characteristics of severe persistent asthma? (define and tx)
- Continuous sx, uses SABA multiple times per day, frequent exacerbations, limited physical activity
- TX = high dose ICS+long acting B2 agonist for systemic steroids if needed, SABA for acute sx
Describe dyskinetic cilia syndrome (3)
- causes bronchiesctatsis and chronic sinusitis
- associated with male infertility
- If seen with situs inversus, look for Kartagener syndrome
What are steroids and when are they used?
4; physiology, inhaled, systemic, SE
- Reverses regulation of B receptors, prevents migration of inflammatory cells, prevents cytokine and histamine production
- Inhaled = fluticasone, use for long term prevention of sx
- Systemic = prednisone, use in short bursts or to prevent sx in severe asthmatics
- Side effects = cough, thrush, growth suppression etc
What is a B agonist and when is it used?
4; physiology, short-acting, long-acting, SE
- Stimulates B2 receptors causing bronchodilation, stabilize mast cells
- Short-acting: albuterol, epi used to stop sx of asthma
- Long-acting: formoterol/salmeterol, used to px symptoms, long term
- SE = tachycardia, palpitations, tremors, dizzy, HA, Nausea, decrease in K, increase glucose
What are mast cells stabilizers and when are they used? (4 physiology, types, use, SE)
- inhibits degranulation of mast cells and mediator release from eosinophils, neutrophils, macros, and monos, do not dilate bronchioles
- cromolyn/nedocromil
- Can be used before exercise to prevent E/A or as an additional alt TX for asthma
- SE = bad taste, dry mouth, pharyngitis, cough, N, Heacache
What are leukotriene modifiers and when are they used? (4; define, types, use, SE)
- Block leukotriene synthesis to prevent allergy response, broncho constriction, and mucous production
- Montelukast/zafirlukast/zileuton (singulair)
- used to prevent allergic rhinitis/persistent asthma
- SE = headaches, n, abdopain, infection, dyspepsia, increase ALT
Describe the clinical course and TX for bronchiolitis
(6) Define, common age, sx, tx, x-ray
- Bronchiole inflammation caused by viral infection RSV
- Common in children <2years, increase risk in premies, neonates, underlying disease
- sx = rhinitis, cough, development of respiratory distress (tachypnea, use of accessory muscles, noisy/raspy breathing, wheezes, fever)
- Supportive care and hospitalize if needed
- Synagis to px RSV in high risk infants
- Hyperinflation on X-ray
What are the clinical characteristics of bronchitis? (5)
Define, viral, bacterial, s/s, tx
- Inflammation of the lower airways, can be acute or chronic
- VIRAL = rhino, RSV, parainfluenza
- BACTERIAL = mycoplasma, pneumo, chamydiophilia pneumo, pseudomonas (in kids with CF)
- s/s = dry cough, substernal discomfort, SOB, possible reproductive cough, low or no fever, URI symptoms, fine/moist rales/rhonchi
- TX = supportive, antibiotics if bacterial
What are the characteristics of croup? (4)
- Acute upper resp airway inflammation and obstruction
- 6-36 months, peak incidence age 2
- Barking cough, URI sx, fever, stridor, sx worse at night, possible dyspnea
- symptomatic relief: cold,steam, humidity
What is the tx of croup? (3)
What is radiologic sign (1)
- Corticosteroids: dexamethasone 1-2mg/kg/day
- bronchodilator
- hospitalize if severe
- steeple sign
What are the causes of pneumonia?
Viral vs. Bacterial (ages)
- VIRAL = RSV, CMV, influ, rhino = ALL AGES
2. Bacterial = group B strep, gram - neonates = group b strep, listeria 1-3mo = strep pneumo, chlamydia, staph 4mo-5yr = strep pneumo, HIB, M. pneumo >5 years = mycoplasma pneumo, chlamydophilia pneumo and S. Pneumo Mycoplasma is usually mild
What are the s/s of pneumonia? (11)
- cough
- wheeze
- URI sx
- chest pain
- high fever (bacterial)
- GI sx
- tachypnea
- crackles, pleural effusion
- dullness
- retractions,
- nasal flaring