Pulm function tests- exam 3 Flashcards

1
Q

What does the Fowler’s test give us a measure of, and how does it work?

A

Anatomical deadspace; Patient inhales a normal breath from FRC of 100% O2, on expiration a nitrogen meter measures the %N2 being exhaled. The volume exhaled at the Midpoint of the transitional phase gives us a measure of anatomical deadspace

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2
Q

What does the Nitrogen Washout Test measure, and how does it work

A

even/uneven ventilation, gives us indication of how healthy/unhealthy lungs are.

Patient breathes in 100% O2, nitrogen meter measures the amount of N2 with each exhalation. Patient keeps doing this until the N2% is about 2.5% which.

If patient takes too long to reach 2.5% it shows they have unhealthy lungs

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3
Q

What is considered a normal Nitrogen Washout Test?

A

<7 minutes

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4
Q

What does the Expiratory Flow Curve tell us

A

Normal, vs Restrictive vs. Obstructive lung disease

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5
Q

How would the expiratory flow curve FVC of a patient with emphysema compare to normal

A
  • lower peak expiratory flow rate
  • higher lung volume
  • higher RV
  • lower vital capacity
  • prolonged downward slope of the effort independent portion of the curve
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6
Q

How would the expiratory flow curve FVC of a patient with restrictive lung disease compare to normal

A
  • lower peak expiratory flow rate
  • lower lung volumes
  • lower vital capacity
  • lower RV
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7
Q

What is an example of a Fixed Flow-Volume Loop? Does it affect inspiration or expiration?

A

endotracheal tube

Both insp and exp. : the fixed inner lumen diameter limits the flow rate on inspiration and expiration. looks like top/bottom of the curves are chopped off

Can be intra or extrathoracic in source

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8
Q

What is an example of a variable intrathoracic flow-volume loop? Does it affect inspiration or expiration?

A

Forced expiration, emphysema, asthma

Only exists on the expiratory cycle. the increased positive pressure of forced expiration causes collapse of the small airways which limits expiration. inspiration is unaffected

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9
Q

What is an example of variable extrathoracic flow-volume loop? Does it affect inspiration or expiration?

A

Obstruction of trachea and upper airway; paralyzed vocal cords

Only affects inspiration. The low negative airway pressure causes collapse of the weak upper airway.

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10
Q

What does FEV1 stand for

A

Forced expiratory volume in 1 second,

The maximal amount of air you can get out of the lung using maximal effort in a period of 1 second

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11
Q

What does FVC stand for

A

Forced vital capacity

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12
Q

What does the FEV1/FVC ratio tell us

A

What % of vital capacity we can forcibly exhale in a period of 1 second.

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13
Q

What is a normal FEV1/FVC ratio

A

80%

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14
Q

What is the FEV1/FVC ratio in this image? What would it indicate?

A

76%
FEV1 = 3.8L
FVC= 5L

normal lungs

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15
Q

In obstructive lung disease FEV1/FVC is typically

A

Low

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16
Q

In restrictive lung disease FEV1/FVC is typically

A

Normal

FVC is low, but the FEV1/FVC ratio is the same as normal

17
Q

What is the FEV1/FVC ratio in this image? What would it indicate?

A

83%

FEV1= ~2.5L
FVC= 3L

example of restrictive lung disease. Low FVC but Normal FEV1/FVC ratio

18
Q

What is the FEV1/FVC ratio in this image? What would it indicate?

A

87%

FEV1= ~1.75L
FVC= 2L

example of restrictive lung disease. Low FVC but high/normal FEV1/FVC ratio

19
Q

What is the FEV1/FVC ratio in this image? What would it indicate?

A

~43%

FEV1= 1.5L
FVC= 3.5L

example of COPD/emphysema. long expiratory time is indicative of obstructive lung disease

20
Q

Normal exhalation is highly reliant on what force?

A

Elastic recoil

21
Q

Which obstructive disease is reversible by bronchodilators

22
Q

Which obstructive disease is not responsive to bronchodilators

A

COPD/emphysema

23
Q

Which obstructive disease is partially reversible by bronchodilators

A

chronic bronchitis

24
Q

PFTs in asthma would look like what
(FEV1, FVC, FEV1/FVC, TLC, RV, FRC, DLCO)

A
  • FEV1 = ↓
  • FVC = ↓
  • FEV1/FVC = ↓
  • TLC = N or ↑
  • RV = ↑
  • FRC = N or ↑
  • DLCO = N
25
Q

PFTs in a patient with COPD would look like what
(FEV1, FVC, FEV1/FVC, TLC, RV, FRC, DLCO)

A
  • FEV1 = ↓
  • FVC = N or ↓
  • FEV1/FVC = ↓
  • TLC = N or ↑
  • RV = ↑
  • FRC = N or ↑
  • DLCO = N or ↓
26
Q

PFTs in a patient with fibrosis would look like what
(FEV1, FVC, FEV1/FVC, TLC, RV, FRC, DLCO)

A
  • FEV1 = ↓
  • FVC = ↓
  • FEV1/FVC = N or ↑
  • TLC = ↓
  • RV = ↓
  • FRC = ↓
  • DLCO = ↓
27
Q

PFTs in a patient with muscle weakness would look like what
(FEV1, FVC, FEV1/FVC, TLC, RV, FRC, DLCO)

A
  • FEV1 = ↓
  • FVC = ↓
  • FEV1/FVC = N or ↑
  • TLC = ↓
  • RV = N or ↑
  • FRC = N
  • DLCO = N
28
Q

PFTs in a patient with kyphoscoliosis would look like what
(FEV1, FVC, FEV1/FVC, TLC, RV, FRC, DLCO)

A
  • FEV1 = ↓
  • FVC = ↓
  • FEV1/FVC = N or ↑
  • TLC = ↓
  • RV = N or ↓
  • FRC = ↓
  • DLCO = N
29
Q

From RV to TLC, the first portion of the lung to fill would be the ______

A

apex first

30
Q

Inspiring from RV to TLC, the last portion of the lung to fill would be the _____

31
Q

Exhaling from TLC to RV, the first portion of the lung to empty would be the ____

A

base first

32
Q

Exhaling from TLC to RV, the last portion of the lung to empty would be the _____

33
Q

What is closing capacity

A

closing volume + RV = closing capacity

The volume of air remaining in the lung when small airways at the base of the lung collapse

34
Q

What is closing volume

A

the volume remaining in the apex of lung that can be removed after small airways have collapsed

35
Q

Which lung volumes change with age

A
  • closing capacity increases
  • RV increases
  • ERV slight increase
36
Q

Why does WOB increase as we age?

A

As we age, closing capacity increases. at about age 55+ the CC is higher than ERV, so they never reach ERV without increased effort. Harder for them to move air

Every breath, small airways collapse as they lose elastic recoil as we age