Public health Flashcards
what is primary disease prevention
prevention of disease onset - target risk factors
what is secondary disease prevention
early detection and optimise progression such as screening
what is tertiary disease prevention
effective symptom management and slowing of progression with things such as medication and surgery
what is quintenary disease prevention
prevention of overmedicating the patient
what is the prevention paradox
measures to improve public health will have little effect on most people
what is a tests sensitivity
it is the correct identification of a disease
how do you work out the sensitivity
true positive / (true positive + false negative)
what is a tests specificity
how well it correctly excludes negative results
how do you work out a tests specificity
True negative/ (true negative + false positive)
what is the positive predive value
it is all those who are positive who tested positive
how do you work out the positive predicted value
True positive/ (true positive + false positive)
what is the negative predictive value
it is all those who are negative who test negative
how do you work out the negative predictive value
True negative/(true negative + false negative)
what are the criteria for a successful screen
WILSON JUNGNER
Important problem
Available diagnosis and treatment facility
Treatable
recognisable latent stage
obvious diagnosis test
general public accepted
economically viable
natural history of untreated disease known
issued agreed policy (who to treat)
continuously done (not abruptly stopped)
what is lead time bias
this is that screening earlier gives an apparent increase in life expectancy
what is length time bias
this is slower progressing diseases are more likely to be picked up on screening than rapidly progressing ones
what are the types of study design
ecological
cross section
case control
cohort
randomized control trial
systematic review
what is an ecological study
it is an observational study - censes, population data
what are positives and negatives of an ecological study
positives: readily available data, shows correlation
negatives: cant show causation, biases and other confounders
what is a cross sectional study
it is a retrospective observational study, stops at a point in time and looks at risk factors and disease development at this time period
- identified prevalence
what are positives and negatives of a cross sectional study
positives: large samples, Data on all variables are only collected at one time point, Multiple outcomes and exposures can be studied, quick and inexpensive
negatives: reverse causality can occur, there can be length time bias, cant use for rare diseases
what is a case control study
this is a retrospective study which is establishing risk factors and disease relationship with a positive and negative group
- identifies predictors of outcomes: odds ratio often used
what are positives and negatives of a case control trial
positives: rapid and are good for rare diseases
negatives: reverse causation and are bias prone
what is a cohort study
it is a prospective longitudinal study: uses positive and negative groups which are followed up with exposure or nor not over time