PT - Transport Across Cell Membranes Flashcards
1
Q
What are the 4 major membrane proteins?
A
- Channels
- Transporters
- Receptors
- Structural Proteins
2
Q
What conformation do proteins adopt to cross the hydrophobic core of the lipid bilayer?
A
α-helical conformation
3
Q
What acts to anchor membrane proteins in the bilayer?
A
Transmembrane helices
4
Q
How do polar solutes move across the membrane?
A
Amphipathic helices cluster together to produce a polar route across the bilayer
5
Q
What occurs when a Ligand is added to a Ligand-gated channel?
A
Channel rotates and Serine is replaced with Lysine, which acts to block the channel
6
Q
How is the calcium pump structured?
A
10 α-helices cross the bilayer
2 Ca2+ ions being transported across the bilayer
Binding site for ATP is present
