Psychosis Neurobiology Flashcards
A patient believing his parents are trying to poison him due to government interference is an example of what?
Paranoid delusion
A patient believing that news about world leaders phones being tapped are actually talking about him is an example of what?
Ideas of reference
A patient who hears voices telling him to not think about important information he has been given is an example of what?
Functional hallucination
A patient believing he must not think about important thoughts as other people have access to them is an example of what?
Thought broadcasting
What is heritability?
Proportion of observable differences in a trait between individuals due to genetic differences
A childhood viral CNS infection can increase schizophrenia risk by 25%. True/false?
False - 50%
What effect does schizophrenia have on ventricle size?
It increases it
What imaging is used to investigate white matter in the brain?
Diffusion tensor imaging
Schizophrenia is thought to be caused by an increase in which neurotransmitter?
Dopamine
Give some examples of typical antipsychotics
Chlorpromazine
Thioridazine
Haloperidol
Typical antipsychotics work by inhibiting which receptor?
Dopamine 2
Atypical antipsychotics are more/less likely to induce extra-pyramidal side effects.
Less likely
Atypical antipsychotics produce a high D2 to 5-HT ratio. True/false?
False - high 5-HT to D2 ratio
Give some examples of atypical antipsychotics
Olanzapine
Risperidone
Quetiapine
Clozapine
Why may typical antipsychotics cause sexual dysfunction?
As prolactin secretion is under inhibitory control by dopamine - cause hyperprolactinaemia
