Psychosis and schizophrenia Flashcards

1
Q

What is psychosis?

A

Represents inability to distinguish between symptoms of delusion, hallucination and disordered thinking from reality

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2
Q

What is the clinical presentation of hallucinations?

A

Have full force and clarity of true perception
Not willed or controlled
Located in external space
Auditory, visual, tactile, olfactory, gustatory

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3
Q

What are delusional beliefs?

A

Unshakable idea or belief which is out of keeping with the person’s social or cultural background; it is help w extraordinary conviction

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4
Q

What are the types of delusions?

A

Grandiose
Paranoid
Hypochondriacal
Self referential

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5
Q

What conditions can have psychotic symptoms?

A

Schizophrenia
Delirium
Severe affective disorder- depression or mania

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6
Q

Diagnostic criteria for schizophrenia- At least 1 of the following, in the absence of organic or affective disorder

A

Auditory hallucination
Broadcasting of thoughts
Control of thoughts- insertion of withdrawal
Delusional beliefs

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7
Q

Diagnostic criteria for schizophrenia- at least 2 of the following

A

Persistent hallucinations in any modality, when occurring every day for at least a month
Neologisms, breaks or interpolations in the train of thought, resulting in incoherent pr irrelevant speech
Catatonic behaviours
Negative symptoms- marked apathy, paucity of speech, blunting or incongruity of emotional response

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8
Q

What is the differential for schizophrenia?

A

Delirium or acute organic brain syndrome

Affective psychoses

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9
Q

What are the types of schizophrenia?

A
Paranoid schizophrenia
Hebephrenic schizophrenia
Catatonic schizophrenia
Undfferentiated schizophrenia
Post-schizophrenic depression
Residual schizophrenia
Simple schizophrenia
Other schizophrenia
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10
Q

What is the most common cause of psychosis?

A

Schizophrenia

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11
Q

What is the common age of onset of schizophrenia?

A

15-35

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12
Q

What are the signs and symptoms of schizophrenia?

A

Postive- hallucinations, delusions, disordered thinking

Negative- apathy, lack of interest, lack of emotion

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13
Q

What are the good prognostic factors for schizophrenia?

A
Absence of FH
Good premorbid function
Clear precipitant
Acute onset
Mood disturbance
Prompt treatment
Maintenance of initiative and motivation
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14
Q

What are the bad prognostic factors for schizophrenia?

A

Slow insidious onset

Childhood onset

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15
Q

What are the possible biological aetiological factors of schizophrenia?

A
Genetics and family history
Neurochemistry
Obstetric complications
Maternal influenza
Malnutrition
Winter birth
Substance misuse
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16
Q

What is the initial pharm treatment of schizophrenia?

A

Antipsychotics, continued for at least 18 months

If poor response, determine adherence and inter-substance reactions, and change if ineffective

17
Q

What is the treatment of an acute exacerbation of schizophrenia?

A

Amisulpride, olanzapine, or risiperidone for at least 4 weeks

18
Q

What is the treatment of treatment resistant schizophrenia?

A

Clozapine

19
Q

What psychological therapies can be used for schizophrenia?

A

CBT
Cognitive remediation
Family intervention