Psychopharmacology Flashcards
1
Q
ANTIDEPRESSANTS
A
2
Q
SSRI’S
A
MOA: Inhibit re-uptake of serotonin from the synaptic cleft into the pre-synaptic neurones and therefore SSRI’s increase the concentration of serotonin in the synaptic cleft.
Slow onset of action, thus typically takes 4-8 weeks to have desired effects.
Side effects:
- SEXUAL DYSFUNCTION (Common)
- GI upset
- Drowsiness
- Hyponatraemia and SIADH
- QT interval prolongation
Caution and CI’s:
- Should be omitted in Mania
- Should be used with caution when treating adoscents and children
- In cardiac disease - sertraline is the safest
- DO NOT CO-PRESCRIBE SSRI AND HEPARIN/WARFARIN
3
Q
Serotonin and Noradrenaline Reuptake Inhibitors (SNRIs)
A
