Psychiatry

Question 1

Bipolar I

Answer 1

MANIA with or without depression for at least 1 wk

Question 2

Bipolar II

Answer 2

Depression and Hypomania

Question 3

Schizotypal personality disorder

Answer 3

Magical thinking, weird but will interact

Question 4

Lewy body histology

Answer 4

Cluster of round, dense cells with eosinophilic core and clear halo

Question 5

Huntington’s

Answer 5

Chr 4 CAG repeats
Substantia Nigra

Question 6

Dementia post-cornea transplant

Answer 6

Creutzfeldt Jakob
Hemiballismus

Question 7

Pick’s disease

Answer 7

Frontal lobe atrophy
Disinhibition

Question 8

Alzheimer’s

Answer 8

Decreased Act in Nucleus Basalis of Meynert
Bad Apo-E4

Question 9

Somatization

Answer 9

Psychological trigger gets them sick
No medical finding (pain in 4 parts, 2 GI)

Question 10

Conversion disorder

Answer 10

Neurological manifestation of internal conflict
Triggered by stressor, Indifferent to it

Question 11

Factitious disorder

Answer 11

Fake illness to get attention, seeks medical treatment and has lots of medical knowledge
Aka Muchausen
Malingering is for monetary gain, grift

Question 12

Sublimation

Answer 12

Bar fighter becomes pro boxer
Socially unacceptable impulses unconsciously transformed to acceptable things

Question 13

Transference

Answer 13

Patient views doc as a parent
Counter-transference is the reverse

Question 14

Reaction formation

Answer 14

Unconsciously act opposite of feelings
Tears on a clown

Question 15

Isolation of affect

Answer 15

Isolate feelings to keep on functioning (Tech)

Question 16

Atypical depression

Answer 16

Hypersomnia, ANXIETY, sensitivity to rejection, hypochondriasis

Question 17

Serotonin syndrome

Answer 17

Clonus, hyperthermia, diarrhea
Tx w/ benzos

Question 18

TCA used for OCD

Answer 18

Clomipramine

Question 19

Tx for TCA intoxication

Answer 19

NaHCO3- (stabilizes cardiac cell membrane)

Question 20

TCA well tolerated in elderly

Answer 20

Nortriptyline (fewer anti-cholinergic effects)

Question 21

TCA for nocturnal enuresis

Answer 21

Imipramine (im-a-peeing)

Question 22

MAOi used for parkinsons

Answer 22

Selegiline: blocks conversion of DA

Question 23

Mirtazapine

Answer 23

a2 Blocker
Increases release of NE, 5HT
AE: sedation and weight gain

Question 24

Typical antipsychotics

Answer 24

Blocks DA more than anything, Positive Sx
Haloperidol, pimozide, trifluoperazine, fluphenazine, thioridazine, chlorpromazine

Question 25

Eye effects with typical anti-psychotics

Answer 25

Chlorpromazine: corneal deposits
Thioridazine: retinal deposits

Question 26

Treatment for EPS

Answer 26

Acute dystonia (immediate), Tardive: Benztropine
Akathesia: Benzos, b-Blockers

Question 27

NMS

Answer 27

Muscle rigidity, fever, encephalopathy, unstable vitals, elevated liver enzymes
Tx w/ Dantrolene

Question 28

Atypical antipsychotics

Answer 28

Target 5HT and Negative Sx
Olanzapine, clozapine, quetiapine, risperidone, aripirazole, ziprasidone

Question 29

Agranulocytosis drugs

Answer 29

Clozapine (atypical antipsychotic)
Carbamazepine

Question 30

Atypical antipsychotics causing the most metabolic symptoms

Answer 30

Pines
Clozapine, olanzapine, quetiapine

Question 31

Atypical antipsychotic causing hyperprolactinemia

Answer 31

Risperidone
Amenorrhea, galactorrhea, gynecomastia

Question 32

SE of lithium

Answer 32

Hypothyroidism, Ebstein, nephrogenic DI

Question 33

Lithium interactions

Answer 33

Nephrotoxic agents: Thiazides, NSAIDs(?)

Question 34

Tx for Tourette

Answer 34

Antipsychotics. Risperidone, fluphenazine

Question 35

When does TD happen

Answer 35

2-4 days after last drink

Question 36

Tx for alcoholism

Answer 36

Acamprosate
naltrexone (reduces cravings)

Question 37

Benzo vs barbiturate MOA

Answer 37

Benzos increase FREQUENCY of opening
Barbs increase duration

Question 38

Naltrexone

Answer 38

Used for opioid withdrawal
Reduces EtOH cravings

Question 39

Tx for cocaine intoxication

Answer 39

a-Blockers, benzos