Psychiatry Flashcards
Bipolar I
MANIA with or without depression for at least 1 wk
Bipolar II
Depression and Hypomania
Schizotypal personality disorder
Magical thinking, weird but will interact
Lewy body histology
Cluster of round, dense cells with eosinophilic core and clear halo
Huntington’s
Chr 4 CAG repeats
Substantia Nigra
Dementia post-cornea transplant
Creutzfeldt Jakob
Hemiballismus
Pick’s disease
Frontal lobe atrophy
Disinhibition
Alzheimer’s
Decreased Act in Nucleus Basalis of Meynert
Bad Apo-E4
Somatization
Psychological trigger gets them sick
No medical finding (pain in 4 parts, 2 GI)
Conversion disorder
Neurological manifestation of internal conflict
Triggered by stressor, Indifferent to it
Factitious disorder
Fake illness to get attention, seeks medical treatment and has lots of medical knowledge
Aka Muchausen
Malingering is for monetary gain, grift
Sublimation
Bar fighter becomes pro boxer
Socially unacceptable impulses unconsciously transformed to acceptable things
Transference
Patient views doc as a parent
Counter-transference is the reverse
Reaction formation
Unconsciously act opposite of feelings
Tears on a clown
Isolation of affect
Isolate feelings to keep on functioning (Tech)
Atypical depression
Hypersomnia, ANXIETY, sensitivity to rejection, hypochondriasis
Serotonin syndrome
Clonus, hyperthermia, diarrhea
Tx w/ benzos
TCA used for OCD
Clomipramine
Tx for TCA intoxication
NaHCO3- (stabilizes cardiac cell membrane)
TCA well tolerated in elderly
Nortriptyline (fewer anti-cholinergic effects)
TCA for nocturnal enuresis
Imipramine (im-a-peeing)
MAOi used for parkinsons
Selegiline: blocks conversion of DA
Mirtazapine
a2 Blocker
Increases release of NE, 5HT
AE: sedation and weight gain
Typical antipsychotics
Blocks DA more than anything, Positive Sx
Haloperidol, pimozide, trifluoperazine, fluphenazine, thioridazine, chlorpromazine
Eye effects with typical anti-psychotics
Chlorpromazine: corneal deposits
Thioridazine: retinal deposits
Treatment for EPS
Acute dystonia (immediate), Tardive: Benztropine
Akathesia: Benzos, b-Blockers
NMS
Muscle rigidity, fever, encephalopathy, unstable vitals, elevated liver enzymes
Tx w/ Dantrolene
Atypical antipsychotics
Target 5HT and Negative Sx
Olanzapine, clozapine, quetiapine, risperidone, aripirazole, ziprasidone
Agranulocytosis drugs
Clozapine (atypical antipsychotic)
Carbamazepine
Atypical antipsychotics causing the most metabolic symptoms
Pines
Clozapine, olanzapine, quetiapine
Atypical antipsychotic causing hyperprolactinemia
Risperidone
Amenorrhea, galactorrhea, gynecomastia
SE of lithium
Hypothyroidism, Ebstein, nephrogenic DI
Lithium interactions
Nephrotoxic agents: Thiazides, NSAIDs(?)
Tx for Tourette
Antipsychotics. Risperidone, fluphenazine
When does TD happen
2-4 days after last drink
Tx for alcoholism
Acamprosate
naltrexone (reduces cravings)
Benzo vs barbiturate MOA
Benzos increase FREQUENCY of opening
Barbs increase duration
Naltrexone
Used for opioid withdrawal
Reduces EtOH cravings
Tx for cocaine intoxication
a-Blockers, benzos
