Psychiatric diseases in pregnancy Flashcards

1
Q

what anxiety medications should be avoided in pregnancy

A

benzodiazepines

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2
Q

SE of benzodiazepines with respect to pregnancy

A

cleft palate

neonatal withdrawal

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3
Q

side effects of valproate

A
neural tube defect
craniofacial defects 
cardiovascular abnormalities
IUGR
reduced IQ 
cleft 
genitourinary anomalies
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4
Q

SE of carbamazepine

A

facial dysmorphism
cardiac anomalies
nail hyperplasia
neural tube defect

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5
Q

SE of lamotrigine

A

cleft

steven Johnson syndrome in breast feeding

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6
Q

SE of lithium

A

cardiac abnormalities
Ebstein’s anomaly
neonatal hypotonia, hypothyroid, hypoglycaemia

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7
Q

is lithium safe in breastfeeding

A

no

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8
Q

SE of atypical psychotics in pregnancy

A

gestational diabetes

IUGR

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9
Q

are typical antipsychotics safe in pregnancy

A

appear to be

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10
Q

what atypical antipsychotics is contraindicated in breastfeeding

A

clozapine

olanzapine

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11
Q

what psychiatric conditions may improve in pregnancy

A

eating disorders

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12
Q

complications of eating disorder and pregnancy

A
IUGR 
prematurity 
hypokalaemia 
hyponatraemia 
metabolic alkalosis
miscarriage
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13
Q

SE of venlafaxine in pregnancy

A

hypertension

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14
Q

SE of paroxetine in pregnancy

A

cardiac anomalies

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15
Q

risks with SSRIs in pregnancy

A

cautious after 20 weeks - pulmonary hypertension

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16
Q

what anti-depressant drug classes are present in breast milk

A

tricyclics

SSRIs (not sertraline)

17
Q

best choice of new anti-depressant in pregnancy

A

sertraline

18
Q

risks of alcoholism in pregnancy

A
miscarriage 
facial deformities 
low IQ
neurodevelopmental delay
epilepsy 
hearing/heart/kidney defect
Wernicke's encephalopathy 
korsakoff syndrome
19
Q

what is korsacoff syndrome

A

thiamine (vit B1 deficiency) - a permanent complication of alcoholism in pregnancy