psych- neurocog Flashcards
wet, wacky, wobbly
NPH
idiopathic cause
decrease reabsorption of CSF
timeline of lewbody dementia
early impairent in executive function
later impairment in memory
characterized by: 1) flucutating cognition 2)hallucinations 3)parkinsonism
**think about patient dx with parkinsons who is not responding to levadopa
NMS sx
FALTER Fever Autonomic instability Leukocytosis Tremor Elevated enzymes (CK, transaminases) Rigors
creutzfeld jakob
rapid decline
myoclonus
akinetic mutism
death in a year
medication for alzheimers
1) cholinesterase inhibitors –> donepazil
2) if severe, add NMDA antag –> mamantadine
avoid anticholinergics
management of severe acute lithium tox
IVF and dialysis
huntington repeats
CAG
dopamine synthesis
phenylalanine –> tyr (+BH4) –> dopa (+B6)–> DOPAMINE –> NE –> epi
primary metabolite of DA?
homovanillic acid
vanillymandelic acid is metab of NE and Epi
apraxia: in what disease and what part of MMSE tests is?
alzheimers, unable to piece together complex executive fx tasks
(diffuse cortical atrophy)
pick up a piece of paper in left hand, fold it, and put it back down
personality seen in temporal lobe epilepsy patient
hyposexual
perseverative
intesnse
viscosity
dreaming is characteristic of which stage of sleep?
REM
what receptors are targets in circadian rythm?
5HT7
what are major targets of atypical antipsychotis?
d4
5ht6
explain hypertensive crisis associated with MAOi?
blocks metabolism of TYR which is precursor to NE and Epi –> pressor effect