neuro- movement disorders

Question 1

shy-drager syndrome

Answer 1

parkinsonism features + autonomic instability

Question 2

distinguishing features of PSP vs parkinsons

Answer 2

(-) tremor

(+) ophthalmoplegia

Question 3

PSP

Answer 3

progressive supranuclear palsy = degen of brainstem, basal g, cerebellu,

seen in older men

similar to parkinsons

Question 4

basic pathophys of huntingtons

Answer 4

CAG repeats on chromosome 4 –> loss of GABA producing neurons in striatum

Question 5

metabolic causes of tremor

Answer 5

hyperthyroidism
hypoglycemia
pheo

Question 6

essential tremor is worse with ______ and better with ______

Answer 6

purposeful movment

etoh!

Question 7

inherited causes of ataxia

Answer 7

fredriechs –> AR, young boys

ataxia telangiectasia –>AR, childhood, similar to fredriechs but telangiectasis

Question 8

tourette’s treatment (pharm)

Answer 8

haloperidol
clonidine
pimozide

Question 9

a parkinsons tremor get’s better with _____ while a cerebellar tremor is considered an _____ tremor and gets better with _________

Answer 9

movement

intention, rest