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Psych/Neuro Flashcards

1
Q

Doxepin brand?

A

Silenor

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2
Q

Class of Doxepin?

A

Tertiary amine TCA

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3
Q

Brand of Nortriptyline?

A

Pamelor

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4
Q

Brand of Amitrityline?

A

Elavil

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5
Q

Class of Amitriptyline?

A

Tertiary amine TCA

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6
Q

Class of Nortriptyline?

A

Secondary amine TCA

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7
Q

Which antidepressants cause QT prolongation?

A

Citalopram and escitalopram

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8
Q

Which antidepressants is preferred in cardiac patients?

A

Sertraline

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9
Q

Which antidepressants should you avoid in pregnant patients?

A

Paroxetine

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10
Q

What are the most sedating antidepressants?

A

Paroxetine, mirtazapine, trazodone

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11
Q

What are the most “activating” antidepressants?

A

Fluoxetine, bupropion

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12
Q

Which antidepressants cause less sexual dysfunctions?

A

Bupropion and mirtazapine

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13
Q

Brand of fluoxetine?

A

Prozac

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14
Q

Maximum daily dose of citalopram / escitalopram?

A

Citalopram = 40mg/day

Escitalopram = 20mg/day

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15
Q

Generic of Zyprexa?

A

Olanzapine

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16
Q

Generic of Latuda?

A

Lurasidone

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17
Q

Generic of Invega?

A

Paliperidone

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18
Q

Which anti-psychs have the highest % of QT prolongation?

A

All psych drugs do, but the highest % are = First gen + Geodon

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19
Q

DOC for a patient w/ hisotry of movement disorders and needs to be on an anti-psych?

A

Quetiapine

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20
Q

Trough levels for lithium?

A

0.6 - 1.2

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21
Q

General Tx plan for bipolar?

A

Mania - valproate, lithium, carbamazepine, lamotrigine

Depression - lithium, lamotrigine

22
Q

5ml of lithium citrate = ____ mg lithium carbonate

23
Q

General Tx for ADHD?

A
  1. Stimulants
  2. Atomoxetine (SNRI)
  3. Guanfacine ER (Intuniv) and clonidine ER (Kapvay)
24
Q

Generic of Lunesta?

A

Eszopiclone

25
Q

Psychosis can occur in parkinson’s patients, but also with which meds?

A

Carbidopa/Levodopa

Dopamine agonists: Pramipexole + Ropinirole

26
Q

Brand of benztropine?

27
Q

Purpose of benztropine?

A

Used for tremors

28
Q

Important parts of Carbidopa/Levodopa dosing?

A

You need at least 70mg of carbidopa to inhibit dopa decarboxylase

29
Q

Generic of Mirapex?

A

Pramipexole

30
Q

Generic of Sinemet?

A

Carbidopa/Levodopa

31
Q

Generic of Requip?

A

Ropinirole

32
Q

What are the COMT inhibitors?

A

Entacapone

33
Q

What are the dopamine agonists?

A

Pramipexole + Ropinirole

34
Q

How is entacapone dosed?

A

200mg for every dose of carbidopa/levodopa

35
Q

How is Alzheimer’s disease treated?

A

Mild - ACh inhibitors (donepezil, rivastigmine, galantamine)

Severe - ACh inhibitors and/or memantine

36
Q

Generic of exelon?

A

Rivastigmine

37
Q

Generic of Aricept?

38
Q

Generic of Lamictal?

A

Lamotrigine

39
Q

What causes seizures?

A

Imbalance of inhibitory GABA and excitatory Glutamate

40
Q

Generic of Topamax?

A

Topiramate

41
Q

Generic of Depakote?

A

Divalproex

42
Q

Therapeutic range of carbamazepine?

43
Q

What kind of testings is required for carbamazepine?

A

HLA-B*1502

44
Q

Generic of Trileptal?

A

Oxcarbazepine

45
Q

Generic of Tegretol?

A

Carbamazepine

46
Q

Valproic acid therapeutic range?

47
Q

BBW for divalproex/valproate?

A

Hepatotoxicity, teratogenic

48
Q

Which anti-epileptic drug is associated with hyponatremia?

A

Carbamazepine/Oxcarbazepine

49
Q

Phenytoin/Fosphenytoin are strong (inducers/inhibitors) of enzymes, what does that mean?

A

Strong inducers - decrease the concentration of many drugs

50
Q

Which AED is an autoinducer?

A

Carbamazepine

51
Q

Valproic acid + Lamotrigine, what happens?

A

Valproic acid will increase concentration of lamotrigine

Most other AED will decrease levels of lamotrigine

52
Q

What kind of mineral deficiency do all AED cause?

A

Calcium + Vit. D

NAPLEX (9 decks)

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