Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

NAPLEX > ID > Flashcards

ID Flashcards

1
Q

Which Abx are time dependent?

A

Beta-lactams

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Which Abx are concentration-dependent?

A

Aminoglycosides, quinolones, dapto

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

MOA of macrolides?

A

Binds to 50s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

BBW of aminoglycosides?

A

Nephro, oto, and neurotoxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Aztreonam covers gram (positive/negative)

A

Negative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Does Aztreonam cover MRSA?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Does Aztreonam cover Pseudo

A

Yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Which carbapenem covers for MRSA?

A

None

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which carbapenem covers for Pseudo?

A

All but Ertapenem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which cephalosporin covers for Pseudo?

A

Cefepime (4th gen) and Ceftazidime (3rd gen)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the only beta-lactam that covers for MRSA?

A

Ceftaroline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Aminoglycosides cover for gram (positive/negative)

A

Negative, unless they are used in synergy with beta-lactam or vanco

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the respiratory quinolones?

A

MLG

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Which quinolones cover for Pseudo?

A

Cipro + levo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which quinolone covers for MRSA?

A

Delafloxacin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

AE of macrolides?

A

QT prolongation + hepatotoxicity

Avoid use with lovastatin/simvastatin w/ clarithromycin or erythromycin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

MOA of tetracycline

A

Binds to 30s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Do aminoglycosides cover for MRSA?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Do aminoglycosides cover for Pseudo?

A

Yes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

MOA of clindamycin?

A

Binds to 50s

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Clindamycin has gram (positive/negative) coverage

A

Gram positive + anaerobes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Generic of Omnicef?

A

Cedinir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Which Abx cover B. fragilis?

A
  1. Flagyl
  2. BL + BLi
  3. Cefotetan, cefoxitin
  4. Carbapenems
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

DOC for treating Acineobacter?

A

Merrem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Which Abx decrease seizure threshold?

A

BL + quinolones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Which Abx cover atypicals?

A

Zithromax, tetracyclines, quinolones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

When do you stop Abx prior to surgery?

A

1hr for Ancef or cefuroxime

2hrs if quinolone or vanco

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

DOC for acute otitis media?

A

Amoxicillin or Augmentin ~90mg/kg/day

29
Q

DOC for COPD exacerbation?

A

Augmentin

30
Q

DOC for outpatient CAP?

A

BL + Macrolide/Doxy oooor respiratory quinolone monotherapy

One of those components are only needed if they have no comorbidities

31
Q

DOC for inpatient CAP?

A

BL + macrolide/respiratory FQ

32
Q

Latent TB tx?

A

R/I once weekly for 12 weeks (daily for rifampin and isoniazid)

Rifampin daily for 4 months

INH daily for 6 or 9 months in pregnant women

33
Q

Active TB tx?

A

RIPE for 2 months

R/I for 4 months

34
Q

RIPE

Which one causes orange-red discoloration?

A

Rifampin

35
Q

RIPE

Which one causes peripheral neuropathy?

A

Isoniazid

36
Q

RIPE

Which one requires the use of Vit. B6?

A

Isoniazid to decrease peripheral neuropathy

37
Q

RIPE

Which one causes optic neuritis?

A

Ethambutol

38
Q

DOC for infective endocarditis?

A

Vary, but needs 4-6 weeks of treatment

39
Q

DOC for infective endocarditis dental prophylaxis?

A

Amoxicillin 2g

40
Q

DOC for SBP?

A

Ceftriaxone for 5-7 days

41
Q

DOC for SBP ppx?

A

Bactrim or Cipro

42
Q

DOC for impetigo? (yellow crusting around mouth)

A

Cephalexin

43
Q

DOC for folliculitis/furuncles/carbuncles?

A

Systemic? Use Cephalexin

If already used, bactrim or doxy works too

44
Q

DOC for mild cellulitis

A

Cephalexin

45
Q

DOC for purulent abscesses?

A

Bactrim or doxy

46
Q

DOC for severe puruelent SSTI

A

Vanco or Dapto or Zyvox

47
Q

DOC for necrotizing fascitis?

A

Vanco + BL

48
Q

DOC for bacteruria in pregnant patients?

A

Augmentin or oral cephalosporin

49
Q

DOC for traveler’s diarrhea + blood?

A

Zithromax

50
Q

DOC for syphillis?

A

Bicillin LA 2.4mill

51
Q

DOC for late latent or teriary?

A

Bicillin LA 2.4mill x 3 weeks

52
Q

DOC for neuro or congenital syphillis?

A

Penicillin G aqueous, up to 24 millions units daily x 10-14 days

53
Q

DOC for gonorrhea?

A

Ceftraixone

54
Q

DOC for Chlmaydia?

A

Doxy or Zithromax

55
Q

DOC for rickettsial diseases?

A

Doxycycline generally

56
Q

DOC for traveler’s diarrhea and no blood?

A

Quinolones or Rifaximin

57
Q

Rate of conventional amphotericin B?

A

Dont exceed 1.5mg/kg/day

58
Q

AE of conventional amphotericin B?

A

Mg and Potassium are depleted, nephrotoxicity, infusion related AE

59
Q

When is flucytosine utuilized?

A

In combo w/ amphotericin for cryptococcal meningitis

60
Q

Flucytocin AE?

A

Myelosuppression

61
Q

General AE of all azoles?

A

Increased LFTs, risk of QT prolongation except in isavuconazonium

62
Q

Which azole requires renal adjustments?

A

Fluconazole

63
Q

Which azole causes severe hepatotoxicity?

A

Ketoconazole

64
Q

Which azole causes HF?

A

Itraconazole

65
Q

Which azole causes visual changes and phototoxicity?

A

Voriconazole

66
Q

Which azole has SBECD vehicle in it?

A

Voriconazole and Posaconazole

67
Q

DOC for Aspergillus?

A

Voriconazole

68
Q

Which azole require an acidic environment for absorption?

A

Ketoconazole + itraconazole

69
Q

Acyclovir AE?

A

Nephrotoxicity

NAPLEX (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions